390 Results for "

glucuronide

" in MedChemExpress (MCE) Product Catalog:
Products (390)

390 Results for "glucuronide" in MCE Product Catalog:

Cat. No.: HY-W121901
CAS No.: 41945-43-1
Synonyms: (S)-Naproxen-β-D-glucuronide
Target:  

COX

Research Areas:  

Inflammation/Immunology

Naproxen glucuronide ((S)-Naproxen-β-D-glucuronide) is a non-selective COX inhibitor. Naproxen glucuronide, a metabolite of naproxen, is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same as ibuprofen) that relieves pain, fever, swelling, and stiffness .
loading...
    loading...
Cat. No.: HY-N11429
CAS No.: 79254-98-1
Glycochenodeoxycholic acid 3-glucuronide is a type of steroid glucuronide and a plasma metabolite that can be used in the research of biomarkers for diabetes and hepatocellular carcinoma (HCC) .
loading...
    loading...
Cat. No.: HY-N12394
CAS No.: 118525-47-6
Norwogonin-8-O-glucuronide is a glucuronide that can be isolated from Scutellaria indica. Norwogonin-8-O-glucuronide has anti-inflammatory activity. Norwogonin-8-O-glucuronide is a flavone glycoside. Norwogonin-8-O-glucuronide inhibits NO production in macrophage RAW264.7 cells with an IC50 above 30 μM .
loading...
    loading...
Cat. No.: HY-W766140
Synonyms: 4-Hydroxy duloxetine glucuronide sodium; LY550408 sodium
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

4-Hydroxy duloxetine β-D-glucuronide (4-Hydroxy duloxetine glucuronide) sodium is a major metabolite of Duloxetine (HY-B0161). 4-Hydroxy duloxetine β-D-glucuronide sodium is promising for research of hepatic or renal impairment .
loading...
    loading...
Cat. No.: HY-W767164
Research Areas:  

Cardiovascular Disease

Deferiprone O-β-D-glucuronide sodium is a novel orally active iron chelator. Deferiprone O-β-D-glucuronide sodium can be used to investigate its ability to reduce iron burden in patients with β-thalassemia .
loading...
    loading...
Cat. No.: HY-126423
CAS No.: 36687-76-0
Synonyms: Isorhamnetin 3-O-glucuronide
Isorhamnetin 3-glucuronide is a potent anticancer agent. Isorhamnetin 3-glucuronide shows anti-proliferative activity. Isorhamnetin 3-glucuronide induces Apoptosis and cell cycle arrest at S-phase .
loading...
    loading...
Cat. No.: HY-138011
CAS No.: 1485692-21-4
Synonyms: Dolutegravir glucuronide; DTG glucuronide
Research Areas:  

Others

Dolutegravir O-β-D-glucuronide (Dolutegravir glucuronide) is a compound used for the simultaneous determination of rilpivirine and dolutegravir concentrations in human plasma.
loading...
    loading...
Cat. No.: HY-N1454R
CAS No.: 29741-09-1
Synonyms: Apigenin 7-O-glucuronide (Standard)
Apigenin-7-glucuronide (Standard) is the analytical standard of Apigenin-7-glucuronide. This product is intended for research and analytical applications. Apigenin-7-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively.
loading...
    loading...
Cat. No.: HY-135391S
CAS No.: 1426174-41-5
Synonyms: Ezetimibe glucuronide-d4; Ezetimibe β-D-glucuronide-d4
Ezetimibe phenoxy glucuronide-d4 is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity . Ezetimibe is a potent cholesterol absorption inhibitor .
loading...
    loading...
Cat. No.: HY-123742
CAS No.: 10392-35-5
Purity:  98.33%
Target:  

P-glycoprotein

Research Areas:  

Metabolic Disease

Estradiol 3-sulfate 17-glucuronide potassium is metabolite of estradiol. Estradiol 3-sulfate 17-glucuronide potassium inhibits multidrug resistance protein (MRP) mediated 17β -Estradiol 17-(β -D-Glucuronide) transport with a Ki of 22 μM .
loading...
    loading...
Cat. No.: HY-136307S
Tizoxanide-d4 glucuronide is the deuterium labeled Tizoxanide glucuronide. Tizoxanide glucuronide is the metabolite of Nitazoxanide (HY-B0217) and is cell-permeable to inhibit asexual and sexual stages development of parasite C. parvum .
loading...
    loading...
Cat. No.: HY-G0020S1
CAS No.: 329002-74-6
Synonyms: Nicotine N-glucuronide-d3
Nicotine N-β-D-glucuronide-d3 (Nicotine N-glucuronide-d3) is a deuterium labeled compound.
loading...
    loading...
Cat. No.: HY-172565
Synonyms: SCH 56592 D-glucuronide
Target:  

Drug Metabolite UGT

Research Areas:  

Infection

Posaconazole D-glucuronide (SCH 56592 D-glucuronide) is a glucuronide metabolite of the antifungal agent Posaconazole (HY-17373). Posaconazole D-glucuronide can be formed in human liver microsomes catalyzed by UGT1A4 .
loading...
    loading...
Cat. No.: HY-W587451
CAS No.: 59274-69-0
Synonyms: OCA-3-glucuronide disodium
Target:  

FXR

Research Areas:  

Metabolic Disease

Cholic acid 3-O-glucuronide (OCA-3-glucuronide) disodium is a farnesoid X receptor (FXR) agonist with an EC50 value of 91.5 μM. Cholic acid 3-O-glucuronide is promising for research of bile acid metabolism and detoxification .
loading...
    loading...
Cat. No.: HY-141914S
Cortisol-21-glucuronide-d4 (sodium) is the deuterium labeled Cortisol-21-glucuronide .
loading...
    loading...
Cat. No.: HY-129889
CAS No.: 1351692-92-6
Synonyms: Febuxostat acyl-β-D-glucuronide
Research Areas:  

Metabolic Disease

Febuxostat acyl glucuronide (Febuxostat acyl-β-D-glucuronide) is a metabolite of Febuxostat (HY-14268). Febuxostat is a potent, selective and non-purine xanthine oxidase (XO) inhibitor .
loading...
    loading...
Cat. No.: HY-W040047S
Pregnanediol 3-glucuronide is the main end-metabolite of Progesterone (HY-N0437). Pregnanediol 3-glucuronide is a metabolite of Progesterone formed by hydroxylation and glucuronidation in the liver, with high hydrophilicity and easy excretion through urine. Pregnanediol 3-glucuronide excretion rate of ≥ 9 μmol/24 h can serve as biochemical evidence of ovulation. Pregnanediol 3-glucuronide reflects the quality of the luteal phase, and a level of < 7 μmol/24 h may indicate anovulation or luteal insufficiency. Pregnanediol 3-glucuronide holds significant importance in monitoring female reproductive health, assessing pregnancy, and diagnosing endocrine disorders.
loading...
    loading...
Cat. No.: HY-143915S
Purity:  ≥97.0%
Amitriptyline-N-glucuronide-d3 is the deuterium labeled Amitriptyline-N-glucuronide .
loading...
    loading...
Cat. No.: HY-N12469
CAS No.: 105762-16-1
Gypsogenin 3-O-glucuronide is a glucuronide that can be isolated from Gypsophila. Gypsogenin 3-O-glucuronide has cytotoxic effect on THP-1 cells .
loading...
    loading...
Cat. No.: HY-137339
CAS No.: 112806-33-4
Target:  

Drug Metabolite

Research Areas:  

Others

Amitriptyline N-β-D-glucuronide is an ammonium glucuronide and an urinary excretion metabolite of amitriptyline .
loading...
    loading...