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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
53 Results for "
thyme
" in MedChemExpress (MCE) Product Catalog:
Products (53)
53 Results for "thyme" in MCE Product Catalog:
Cat. No.: HY-P992378
Research Areas:
Cat. No.: HY-182370
CAS No.: 3076612-97-7
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TKP-5 is a PROTAC protein degrader targeting BRD4. TKP-5 can binds to BRD2, BRD3, BRD4 and BRDT, with Kd values of 150 nM, 100 nM and 150 nM for the first three proteins respectively. TKP-5 inhibits the production of thymic stromal lymphopoietin and suppresses the expression of IL-33 mRNA. TKP-5 is applicable to studies related to tape-stripping induced skin injury .
Cat. No.: HY-P992452
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Cat. No.: HY-N7122AR
CAS No.: 89318-88-7
Cat. No.: HY-19299
CAS No.: 245329-99-1
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology
CI-1018 is an orally active selective PDE-4 inhibitor, with IC50 values of 1.1 μM, 35.8 μM, and 73.4 μM against hPDE-4, canine PDE-4, and guinea pig PDE-4, respectively. CI-1018 induces iNOS expression and Apoptosis. CI-1018 induces vascular injury, medial necrosis, hemorrhage, edema, thymic atrophy, ketonuria, and weight loss. CI-1018 can be used in research related to asthma, vasculitis, and mesenteric vasculitis/arteriopathy .
Cat. No.: HY-N16715
CAS No.: 1607436-76-9
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Cat. No.: HY-W275882
CAS No.: 13179-98-1
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1,6-Dimethoxyhexane is an aliphatic ether that serves as a PROTAC linker and fuel additive. 1,6-Dimethoxyhexane is an orally active testicular toxicant. It has no direct toxicity on its own, but exerts toxicity after oxidative metabolism by liver/testicular microsomes to produce 2-Methoxyacetic Acid (MAA). 1,6-Dimethoxyhexane induces apoptosis/necrosis of pachytene spermatocytes, downregulates the expression of HSP70.2, HSP60 and ERp60/PDI A3, and causes spermatogenic tubule degeneration, testicular/thymic atrophy, a sharp decline in epididymal sperm density, and other effects. 1,6-Dimethoxyhexane can be used in studies related to testicular toxicity .
Cat. No.: HY-187612
CAS No.: 168620-45-9
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FR-168888 free base is a Na +/H + exchanger (NHE) inhibitor (Ki=6.4 nM) with weak inhibitory activity against Na +/Ca 2+ exchanger and no cardioprotective effects. FR-168888 free base is widely applicable to studies related to reperfusion-induced ventricular arrhythmias .
Cat. No.: HY-W775388
CAS No.: 101687-28-9
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Cat. No.: HY-182362
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TK-285 is a potent TSLP inhibitor that suppresses the production of TSLP and inhibits the expression of interleukin-33 mRNA. TK-285 exhibits a selective binding preference for the BD1 domains of BRD2, BRD3, BRD4 and BRDT. TK-285 can be used in research related to atopic dermatitis .
Cat. No.: HY-184859
CAS No.: 83704-55-6
1,3,4,6,8-Pentachlorodibenzofuran is a pentachlorinated dibenzofuran congener. 1,3,4,6,8-Pentachlorodibenzofuran exhibits acute toxicity in CF-1 mice. 1,3,4,6,8-Pentachlorodibenzofuran can be used in environmental toxicology research .
Cat. No.: HY-P11699
CAS No.: 179953-98-1
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Cat. No.: HY-P992474
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TAVO101 is a humanized anti-TSLP antibody with an EC50 of 0.19 nM against hTSLP. TAVO101 inhibits STAT5 activation and CCL17 release. TAVO101 carries Fc region mutations that enhance its binding to FcRn while reducing its binding to FcγRI, FcγRIIIA and C1q, thereby attenuating effector functions. TAVO101 reduces the levels of inflammatory markers, cell infiltration and histopathological damage in preclinical models of asthma, psoriasis and atopic dermatitis. TAVO101 can be used for research related to asthma, psoriasis and atopic dermatitis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
