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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
75 Results for "
difficile
" in MedChemExpress (MCE) Product Catalog:
Products (75)
75 Results for "difficile" in MCE Product Catalog:
Cat. No.: HY-128357A
CAS No.: 1275582-98-3
Synonyms: ACX-362E hydrochloride; GLS-362E hydrochloride
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Ibezapolstat hydrochloride is a first-in-class, orally active DNA polymerase IIIC (pol IIIC) inhibitor, with a Ki of 0.325 μM for the DNA pol IIIC from C. difficile. Ibezapolstat hydrochloride is developed for the research of C. difficile infection(CDI) .
Cat. No.: HY-N12228
CAS No.: 114451-31-9
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Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Disease Research Antibacterial Beta-lactam Antibiotics
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Cat. No.: HY-105099R
CAS No.: 129791-92-0
Synonyms: KRM-1648 (Standard); ABI-1648 (Standard)
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Rifalazil (Standard) is the analytical standard of Rifalazil. This product is intended for research and analytical applications. Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase[1]. Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml[3]. Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB)[2].
Cat. No.: HY-156282
CAS No.: 2804045-21-2
Antibacterial agent 158 (compound 6c), a Micrococcin analogue, and is effective against impetigo and C. difficile infection (CDI) .
Cat. No.: HY-172768
CAS No.: 2930140-57-9
SCUT1-2 is a bifunctional antibacterial agent with good oral bioavailability in mice (F=56.8%). SCUT1-2 can kill the vegetative cells of C. difficile with a MIC of 0.06-0.50 μg/mL, and inhibit spore germination in vitro. SCUT1-2 could alleviate the symptoms of weight loss and diarrhea in mice caused by C. difficile infection (CDI) and prevent recurrent CDI .
Cat. No.: HY-100436R
CAS No.: 1025097-10-2
Synonyms: ACT-179811 (Standard)
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Cadazolid (Standard) is the analytical standard of Cadazolid. This product is intended for research and analytical applications. Cadazolid (ACT-179811) is a new oxazolidinone antibiotic with potent activity against Clostridium difficile.
Cat. No.: HY-W749146
CAS No.: 1198782-86-3
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Raja 42 is a gamma lactam antibiotic. Raja 42 is effective against a variety of different bacterias, including Gram-positive and Gram-negative bacteria, such as C. difficile strains .
Cat. No.: HY-B0975S
Synonyms: Phenoxymethylpenicillin-13C6 potassium salt
Cat. No.: HY-W750848
CAS No.: 2469575-54-8
Cat. No.: HY-143454
CAS No.: 65384-76-1
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Germination-IN-1 (compound 11) is a potent germination inhibitor with an IC50 of 4 µM. Germination-IN-2 shows anti-germination activity with 14% germination rate .
Cat. No.: HY-143455
CAS No.: 89846-43-5
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Germination-IN-2 (compound 15) is a potent germination inhibitor with an IC50 of 1.3 µM. Germination-IN-2 shows anti-germination activity with 3% germination rate .
Cat. No.: HY-149610
CAS No.: 3032400-44-2
Antibacterial agent 156 (Compound 57) is a selective and potent bactericidal against C. difficile and targets cell-wall synthesis. Antibacterial agent 156 exhibits bactericidal activity with the minimal inhibitory concentration of 0.5 μg/mL and 1 μg/mL against MIMIC50 (101 strains) and MIC90 (101 strains) .
Cat. No.: HY-B0975AS
CAS No.: 1356837-87-0
Cat. No.: HY-107830R
CAS No.: 1448-36-8
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Cat. No.: HY-W746556
CAS No.: 52886-39-2
Cat. No.: HY-115440R
CAS No.: 1013915-99-5
Synonyms: REP-3123 dihydrochloride (Standard)
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Selegiline (Standard) is the analytical standard of Selegiline. This product is intended for research and analytical applications. Selegiline (Deprenyl) is a potent, selective and irreversible inhibitor of MAO-B, with an IC50 of 51 nM. Selegiline exhibits 450-flod selectivity for MAO-B over MAO-A (IC50=23 μM). Selegiline can be used for the research of Parkinson's disease, Alzheimer's disease and major depressive disorder .
Cat. No.: HY-171005
CAS No.: 1245813-92-6
VPC162134 is an antibacterial agent, that inhibits H. pylori, C. jejuni, MRSA and S. epidermidis with MIC of 2.9, 17.5, 93.3 and 93.3 μM. VPC162134 is an inhibitor for pyruvate ferredoxin oxidoreductase (PFOR) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
