Germination-IN-2
Germination-IN-2 (compound 15) is a potent germination inhibitor with an IC50 of 1.3 µM. Germination-IN-2 shows anti-germination activity with 3% germination rate.
For research use only. We do not sell to patients.
- CAS No.: 89846-43-5
- Formula: C30H45NO3
- Molecular Weight:467.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 89846-43-5
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Molecular Weight 467.68
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Formula C30H45NO3
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SMILES
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NC3=CC=CC=C3)=O)([H])[C@@]4([H])[C@@](C[C@@H]1O)([H])[C@@]5([C@](C[C@@H](CC5)O)([H])CC4)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. Sharma SK, et al. Studies on the Importance of the 7α-, and 12α- hydroxyl groups of N-Aryl-3α,7α,12α-trihydroxy-5β-cholan-24-amides on their Antigermination Activity Against a Hypervirulent Strain of Clostridioides (Clostridium) difficile. Bioorg Med Chem. 2021 Dec 15;52:116503. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)