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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
76 Results for "
initial
" in MedChemExpress (MCE) Product Catalog:
Products (76)
76 Results for "initial" in MCE Product Catalog:
Cat. No.: HY-B0317BS
Synonyms: Amlodipine benzenesulfonate-d4 besylate
Cat. No.: HY-W585933
CAS No.: 16124-24-6
Synonyms: Fru-Ala
Fructose-alanine, an amadori compound, is an aroma precursor that formed in the initial phase of the Maillard reaction (MR). Fructose-alanine can be isolated from tobacco, miso and white wine. Fructose-alanine significantly induces oxidative browning and correlates with Maillard product (furfuryl alcohol) with a roasted and sweet aroma. Fructose-alanine can be used for food industry and tobacco processing research .
Cat. No.: HY-14308
CAS No.: 1064684-44-1
Synonyms: PSI-7851
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GS-9851 (PSI-7851) is a HCV nonstructural protein 5B (NS5B) inhibitor with potential activity for the study of HCV infection. GS-9851 shows good tolerability with initial HCV genotype 1 infection. GS-9851 is rapidly cleared from the body with a half-life of approximately 1 hour .
Cat. No.: HY-B0317BR
CAS No.: 111470-99-6
Synonyms: Amlodipine benzenesulfonate (Standard)
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Amlodipine (besylate) (Standard) is the analytical standard of Amlodipine (besylate). This product is intended for research and analytical applications. Amlodipine besylate (Amlodipine benzenesulfonate), an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine besylate can be used for the research of high blood pressure and cancer .
Cat. No.: HY-11084
CAS No.: 387825-78-7
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SNAP-7941 is a selective antagonist with anxiolytic, antidepressant and appetite suppressant activities. SNAP-7941 showed promising biological activity in initial animal studies. SNAP-7941 targets the melanin concentrating hormone receptor MCH1 and has significant inhibitory potential. SNAP-7941 was shown to inhibit the centrally induced MCH-induced drinking effect in in vivo studies .
Cat. No.: HY-Y0678S
CAS No.: 35564-11-5
Synonyms: Trimethyl phloroglucinol-d3
Cat. No.: HY-121312
CAS No.: 28125-87-3
Synonyms: ST-600
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Flutonidine (ST-600) is a Clonidine (HY-12721) analogue that shows antihypertensive and sympatholytic effects. The initial hypertension produced by Flutonidine is due to stimulation of the peripheral α1, α2 adrenoceptors and the subsequent fall in blood pressure is due to the stimulation of central α2 adrenoceptors. Flutonidine reduces the arrhythmogenic and lethal effects of ouabain. Flutonidine is promising for research of ventricular arrhythmias caused by cardiac glycosides .
Cat. No.: HY-117051
CAS No.: 1046490-67-8
STA-2842 is an inhibitor of heat shock protein HSP90 with potential to inhibit autosomal dominant polycystic kidney disease (ADPKD). ADPKD is caused by inherited mutations in the PKD1 or PKD2 genes that abnormally activate multiple signaling proteins and pathways that regulate cell proliferation. STA-2842 can significantly reduce initial renal cyst formation and kidney growth in mice, and slow disease progression in mice with existing cysts.
Cat. No.: HY-P1409
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Cat. No.: HY-W008129R
CAS No.: 2584-71-6
Cat. No.: HY-W585933S
CAS No.: 1083053-41-1
Synonyms: Fru-Ala-13C6
Cat. No.: HY-168009
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NLRP3-IN-45 (D6) is an inhibitor of NLRP3 inflammasome activation, inhibiting the activity of IL-1β (IC50=41.79 nM). NLRP3-IN-45 exerts its effects without affecting the initial stage of NLRP3 inflammasome activation. NLRP3-IN-45 specifically inhibits the activation of NLRP3 inflammasome in the LPS-induced acute lung injury (ALI) mouse model .
Cat. No.: HY-147927A
CAS No.: 1802891-23-1
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(S)-Human enteropeptidase-IN-1 (Compound 6c) is an orally active enteropeptidase inhibitor with low systemic exposure (IC50 (initial): 26 nM; IC50 (app): 1.8 nM). (S)-Human enteropeptidase-IN-1 promotes increased fecal protein output and effectively reduces body weight in a diet-induced obese (DIO) rat model. (S)-Human enteropeptidase-IN-1 inhibits enteropeptidase via a reversible covalent mechanism and prolongs the enzyme inactivation time. (S)-Human enteropeptidase-IN-1 can be used in anti-obesity research .
Cat. No.: HY-108398BR
CAS No.: 17046-59-2
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Cat. No.: HY-W017189R
CAS No.: 4593-90-2
Cat. No.: HY-Y0306
CAS No.: 12124-97-9
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Ammonium bromide is an inorganic electrolyte additive used in halogen-free magnesium-sulfur battery electrolytes, which serves dual functions as a regulator and a resistance-reducing agent. Ammonium bromide effectively optimizes the interfacial reaction kinetics of batteries by guiding the uniform deposition of magnesium, reducing the activation energy for magnesium ion transport, and decreasing the stripping/deposition overpotential. Ammonium bromide significantly enhances the cycle life and initial discharge capacity of magnesium-sulfur batteries .
Cat. No.: HY-E71329
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Initial cyclization gives (+)-germacrene A in an enzyme bound form which is not released to the medium.
Cat. No.: HY-E71597
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2-Nitroimidazole nitrohydrolase (EC 3.5.99.9) catalyses the initial step in the biodegradation of 2-nitroimidazole by the soil bacterium Mycobacterium sp.
Cat. No.: HY-180755
CAS No.: 75222-07-0
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
