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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
140 Results for "
nonnucleoside reverse transcriptase
" in MedChemExpress (MCE) Product Catalog:
Products (140)
140 Results for "nonnucleoside reverse transcriptase" in MCE Product Catalog:
Cat. No.: HY-19509R
CAS No.: 301297-45-0
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IQP-0528 (Standard) is the analytical standard of IQP-0528. This product is intended for research and analytical applications. IQP-0528 is a highly potent nonnucleoside reverse transcriptase inhibitor (NNRTI). IQP-0528 shows nanomolar activity against both HIV-1 and HIV-2, with an HIV-1 EC50 of 0.2 nM and an HIV-2 EC50 of 100 nM .
Cat. No.: HY-10572A
CAS No.: 154801-74-8
Synonyms: (R)-DMP 266; (R)-EFV; (R)-L-743726
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(R)-Efavirenz ((R)-DMP 266) is a non-nucleoside reverse transcriptase inhibitor that acts by non-competitive inhibition of the viral enzyme. (R)-Efavirenz can be metabolized by CYP2B6 to 8-hydroxyefavirenz in a highly stereoselective manner. (R)-Efavirenz is promising to be a useful probe for the CYP2B6 active site and catalytic mechanisms .
Cat. No.: HY-15350
CAS No.: 148311-89-1
Synonyms: LY 300046 hydrochloride
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Trovirdine hydrochloride (LY300046 hydrochloride) is a selective non-nucleoside HIV-1 reverse transcriptase inhibitor, with an IC50 value of 0.012 μM against the wild-type enzyme. Trovirdine hydrochloride inhibits the replication of both wild-type and mutant HIV-1, and exerts synergistic or additive effects when combined with some antiviral drugs. Trovirdine hydrochloride is applicable to research related to HIV-1 infection .
Cat. No.: HY-123330
CAS No.: 457635-65-3
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GW695634 is an orally active prodrug of GW678248. GW695634 undergoes amidolysis in vivo to release the active ingredient GW678248, thereby inhibiting viral replication. GW678248 is a non-nucleoside reverse transcriptase inhibitor (NNRTi) with potent antiviral activity against Efavirenz (HY-10572)-resistant and Nevirapine (HY-10570)-resistant HIV and AIDS viruses .
Atevirdine is a potent non-nucleoside HIV-1 reverse transcriptase inhibitor. Atevirdine inhibits non-nucleoside reverse transcriptase that leads to viral multiplication .
Cat. No.: HY-182497
CAS No.: 177577-59-2
U 95133 is a non-nucleoside reverse transcriptase inhibitor. U 95133 exhibits activity against both wild-type and mutant HIV-1 reverse transcriptase. U 95133 can be used in studies related to HIV infection .
Cat. No.: HY-118632
CAS No.: 380378-81-4
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BILR 355 is a second-generation nonnucleoside reverse transcriptase inhibitor (NNRTI). BILR 355 is highly specific toward HIV-1 reverse transcriptase (RT). BILR 355 can be used for HIV infections research .
Cat. No.: HY-169207
CAS No.: 3032803-00-9
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NNRT-IN-5 (compund 10d) is an orally available non-nucleoside reverse transcriptase inhibitor .
Cat. No.: HY-107001
CAS No.: 214287-88-4
Synonyms: (S)-DPC 961; DMP 961
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DPC 961 (DMP 961) is a non-nucleoside reverse transcriptase inhibitor (NNRTI). DPC 961 is a potent and specific inhibitor of HIV-1 reverse transcriptase, which inhibits the activity of HIV-1 reverse transcriptase in a non-competitive manner, thereby preventing viral replication. DPC 961 can be used for research on AIDS .
Cat. No.: HY-105491
CAS No.: 135812-34-9
Synonyms: NSC-629243
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UC-38 (NSC-629243) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) with anti-HIV activity .
Cat. No.: HY-142073
CAS No.: 183904-53-2
Synonyms: DHCal A; NSC 678323
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(+)-Dihydrocalanolide A (DHCal A; NSC 678323) is an orally active nonnucleoside inhibitor of Reverse Transcriptase. (+)-Dihydrocalanolide A can be used to HIV infection research .
Cat. No.: HY-131422
CAS No.: 205754-32-1
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(Rac)-8-Hydroxy-efavirenz is a metabolite of Efavirenz (HY-10572), a non-nucleoside HIV-1 reverse transcriptase inhibitor .
Cat. No.: HY-149338
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NNRT-IN-3 (compound 8) is an HIV-1 non-nucleoside reverse transcriptase inhibitor (EC50=0.01 μM) .
Cat. No.: HY-176169
CAS No.: 2892399-89-0
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DC20 is an orally active non-nucleoside reverse transcriptase inhibitor with an EC50 of 0.004 μM aganist HIV-1IIIB .
Cat. No.: HY-117477
CAS No.: 214287-90-8
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DPC-963 is an oral active non-nucleoside reverse transcriptase inhibitor with the IC50 of 18 nM. DPC-963 can be used for study of HIV .
Cat. No.: HY-132508S
CAS No.: 1142096-06-7
Cat. No.: HY-14294
CAS No.: 178979-85-6
Synonyms: S-1153
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Capravirine (S-1153) is an orally active non-nucleoside reverse transcriptase inhibitor (NNRTI) with potent antiviral activity. Capravirine inhibits replication of HIV-1 strains that are resistant to nucleoside/nucleotide reverse transcriptase inhibitors and other NNRTIs. Capravirine is metabolized by the cytochrome P450 enzyme CYP3A4 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
