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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
84 Results for "
5-HT (5-hydroxytryptamine)
" in MedChemExpress (MCE) Product Catalog:
Products (84)
84 Results for "5-HT (5-hydroxytryptamine)" in MCE Product Catalog:
Cat. No.: HY-167639
CAS No.: 132036-90-9
Synonyms: (S)-YM060 free base
Target:
Research Areas:
(S)-Ramosetron ((S)-YM060 free base) is an orally active antagonist of the 5-hydroxytryptamine 5-HT3 receptor. (S)-Ramosetron is promising for research of diseases related to nausea and vomiting, irritable bowel syndrome (IBS) .
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ML 10302 is a potent agonist 5-HT4 receptor with Ki of 1.07 nM. 5-Hydroxytryptamine (5-HT4) receptor agonists stimulate gut motility through cholinergic pathways. ML10302 induces significant prokinesia both in the small bowel and colon through activation of cholinergic pathways. ML 10302 also has the potential for the research of neurology diseases .
Cat. No.: HY-19927A
CAS No.: 1645260-76-9
Target:
Research Areas:
DA-6886 is a 5-Hydroxytryptamine receptor 4 (5-HT4) agonist. DA-6886 induces relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels reveals that it inhibits hERG channel current with an pIC50 value of 4.3, indicating that the compound is 1000-fold more selective for the 5-HT4 receptor over hERG channels. DA-6886 can be used in the study of constipated irritable bowel syndrome .
Cat. No.: HY-148032
CAS No.: 20776-45-8
Synonyms: 5-BT
Target:
Research Areas:
5-Benzyloxytryptamine (5-BT) is a selective partial agonist for 5-hydroxytryptamine 1D/1B (5-HT1D/1B) receptors with an IC50 value of 40 nM for bovine caudate 5-HT1D and reduced affinity for other receptors (5-HT2 IC50>470 nM). 5-Benzyloxytryptamine inhibits adenylate cyclase to decrease neurotransmitter release and downregulate cAMP signaling. 5-Benzyloxytryptamine is promising for research of neurotransmitter imbalance-related disorders like migraine .
Cat. No.: HY-10349AR
CAS No.: 1092679-51-0
Research Areas:
WAY-100635 (maleate) (Standard) is the analytical standard of WAY-100635 (maleate). This product is intended for research and analytical applications. WAY-100635 maleate is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 value of 0.91 nM and Ki value of 0.39 nM. WAY-100635 maleate has pIC50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 maleate is also a potent dopamine D4 receptor agonist .
Cat. No.: HY-10349R
CAS No.: 162760-96-5
Research Areas:
WAY-100635 (Standard) is the analytical standard of WAY-100635. This product is intended for research and analytical applications. WAY-100635 is a potent and selective 5-HT1A Receptor antagonist with a pIC50 of 8.87, an apparent pA2 of 9.71.
WAY-100635 is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 value of 0.91 nM and Ki value of 0.39 nM. WAY-100635 has pIC50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 is also a potent dopamine D4 receptor agonist .
Cat. No.: HY-103116
CAS No.: 133364-62-2
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DV-7028 is a selective 5-hydroxytryptamine2 (5-HT2) receptor antagonist .
Cat. No.: HY-129444
CAS No.: 73423-36-6
Target:
Research Areas:
MD 780236 free base is a substrate and selective inhibitor of monoamine oxidase B (MAO-B), competitive with phenylethylamine and 5-hydroxytryptamine (5-HT) .
Cat. No.: HY-103090
CAS No.: 299433-10-6
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NPS ALX Compound 4a is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM .
Cat. No.: HY-103090A
CAS No.: 1781934-44-8
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Research Areas:
NPS ALX Compound 4a dihydrochloride is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM .
Cat. No.: HY-W010973R
CAS No.: 61-47-2
Cat. No.: HY-121653B
CAS No.: 98205-89-1
Synonyms: DU-29373
Target:
Research Areas:
Flesinoxan hydrochloride is a hypotensive agent and a potent, high affinity and selective 5-hydroxytryptamine1A (5-HT1A) receptor agonist with an EC50 value of 24 nM. Flesinoxan hydrochloride also has effective anxiolytic/antidepressant effects .
Cat. No.: HY-121653R
CAS No.: 98206-10-1
Target:
Research Areas:
Flesinoxan (Standard) is the analytical standard of Flesinoxan. This product is intended for research and analytical applications. Flesinoxan is a hypotensive agent and a potent, high affinity and selective 5-hydroxytryptamine1A (5-HT1A) receptor agonist with an EC50 value of 24 nM. Flesinoxan also has effective anxiolytic/antidepressant effects .
Cat. No.: HY-111200A
CAS No.: 887258-95-9
Synonyms: SCA-136 free base
Research Areas:
Vabicaserin is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM.
Cat. No.: HY-FLA0019A
CAS No.: 199739-10-1
Synonyms: 9-Hydroxyrisperidone palmitate solution
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Paliperidone palmitate solution is mainly composed of Paliperidone palmitate (HY-A0019A). Paliperidone palmitate is an orally effective competitive antagonist of dopamine D2 receptors and 5-hydroxytryptamine 2A (5-HT2A) receptors that can cross the blood-brain barrier. Paliperidone palmitate competitively inhibits the effects of dopamine and 5-hydroxytryptamine by binding to dopamine D2 receptors and 5-HT2A receptors, regulating the balance of the neurotransmitter system and thus exerting antipsychotic activity. Paliperidone palmitate is mainly used in the research field of schizophrenia .
Cat. No.: HY-111200R
CAS No.: 887258-94-8
Synonyms: SCA 136 (Standard)
Target:
Research Areas:
Vabicaserin hydrochloride (Standard) is the analytical standard of Vabicaserin hydrochloride (HY-111200). This product is intended for research and analytical applications. Vabicaserin hydrochloride is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM.
Cat. No.: HY-P703149
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HTR2A; Serotonin Receptor 2A; Prev. HTR2; Serotonin 5-HT-2A Receptor; 5-HT2A; 5-HT2 Receptor; 5-Hydroxytryptamine (Serotonin) Receptor 2A, G Protein-Coupled; 5-HT-2A; 5-Hydroxytryptamine (Serotonin) Receptor 2A; 5-Hydroxytryptamine Receptor 2A; 5-HT-2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703150
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HTR2A; Serotonin Receptor 2A; Prev. HTR2; Serotonin 5-HT-2A Receptor; 5-HT2A; 5-HT2 Receptor; 5-Hydroxytryptamine (Serotonin) Receptor 2A, G Protein-Coupled; 5-HT-2A; 5-Hydroxytryptamine (Serotonin) Receptor 2A; 5-Hydroxytryptamine Receptor 2A; 5-HT-2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P810892
Synonyms: HTR2; 5-hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; Serotonin receptor 2A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
