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Cat. No.: HY-103116

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DV-7028 hydrochloride

DV-7028 is a selective 5-hydroxytryptamine₂ (5-HT₂) receptor antagonist.

For research use only. We do not sell to patients.

CAS No.: 133364-62-2
Formula: C₂₁H₂₆ClFN₄O₃
Molecular Weight:436.91

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

DV-7028 hydrochloride Chemical Structure

CAS No.: 133364-62-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

DV-7028 is a selective 5-hydroxytryptamine₂ (5-HT₂) receptor antagonist^[1].

IC₅₀ & Target

5-HT₂ Receptor

All 5-HT Receptor Isoforms :

In Vivo

DV-7028 (0.1 mg/kg, intravenously) reduced the frequency of cyclic flow reductions by 77% in dog and improved the nadir of coronary blood flow velocity that indicated the severity of cyclic flow reductions ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 133364-62-2
Molecular Weight 436.91
Formula C₂₁H₂₆ClFN₄O₃
SMILES

O=C(N1CCN2CCC(C(C3=CC=C(F)C=C3)=O)CC2)N=C(CCCC4)N4C1=O.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tanaka T, et al. Combined effect of the 5-HT2 receptor antagonist DV-7028 and aspirin or heparin on coronary cyclic flow reductions in dogs. Cardiovasc Res. 1993 Jul;27(7):1374-9. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
References

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DV-7028 hydrochloride

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

DV-7028 hydrochloride Related Classifications

HY-103116 Related Classifications