119 Results for "

HIV Integrase

" in MedChemExpress (MCE) Product Catalog:
Products (119)

119 Results for "HIV Integrase" in MCE Product Catalog:

Cat. No.: HY-107485R
CAS No.: 1568-80-5
Research Areas:  

Infection

HIV-1 integrase inhibitor 8 (Standard) is the analytical standard of HIV-1 integrase inhibitor 8 (HY-107485). This product is intended for research and analytical applications. HIV-1 integrase inhibitor 8 is a HIV-1 integrase inhibitor, compound 8 .
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Cat. No.: HY-153247
CAS No.: 2081127-77-5
Target:  

HIV Integrase

Research Areas:  

Infection Inflammation/Immunology

GSK3839919A is a potent and allosteric HIV-1integrase inhibitor .
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Cat. No.: HY-N15327
CAS No.: 138355-07-4
Hyrtiosal, found in the marine sponge Hyrtios erectus, is an inhibitor of the N-terminal domain (NTD) of HIV-1 integrase (HIV-1 IN) with an IC50 value of 9.60-0.86 μM. Hyrtiosal binds to the Ser17, Trp19, and Lys34 sites on the NTD of HIV-1 IN, inhibiting the binding of HIV-1 viral DNA to integrase and interfering with the formation of the pre-integrated complex of HIV-1. Hyrtiosal is promising for research of anti-HIV agents .
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Cat. No.: HY-17605S2
Synonyms: GS-9883-d4
Bictegravir-d4 is a deuterium of Bictegravir (HY-17605). Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM .
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Cat. No.: HY-163177
Target:  

HIV

Research Areas:  

Infection

HIV-1 inhibitor-63 (compound S17) is a potent HIV-1 inhibitor. HIV-1 inhibitor-63 inhibits integrase-Ku70 complex formation with an IC50 value of 12 µM. HIV-1 inhibitor-63 inhibits HIV-1 post-integration DNA repair .
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Cat. No.: HY-10353S
CAS No.: 2712343-38-7
Raltegravir-d4 is deuterium labeled Raltegravir. Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection.
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Cat. No.: HY-14740S
Synonyms: GS-9137-d8; JTK-303-d8; D06677-d8
Elvitegravir-d8 is deuterium labeled Elvitegravir. Elvitegravir (GS-9137; JTK-303; D06677) is an HIV integrase inhibitor for HIV-1IIIB, HIV-2EHO and HIV-2ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively.
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Cat. No.: HY-A0162R
CAS No.: 120138-50-3
Research Areas:  

Infection

Bictegravir (sodium) (Standard) is the analytical standard of Bictegravir (sodium). This product is intended for research and analytical applications. Bictegravir sodium is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir sodium exhibits potent and selective anti-HIV activity and low cytotoxicity .
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Cat. No.: HY-10353S1
CAS No.: 1100750-98-8
Synonyms: MK-0518-d6
Raltegravir-d6 is a deuterated labeled Raltegravir . Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection.
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Cat. No.: HY-P2379
CAS No.: 172546-75-7
Target:  

HIV Integrase

Research Areas:  

Infection

His-Cys-Lys-Phe-Trp-Trp is an inhibitor for the human immunodeficiency virus (HIV) integrase with an IC50 of 2 μM .
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Cat. No.: HY-17605S4
CAS No.: 2171092-56-9
Synonyms: GS-9883-d7
Bictegravir-d7 (GS-9883-d7) is deuterium labeled Bictegravir. Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM.
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Cat. No.: HY-W103287
CAS No.: 6890-08-0
Target:  

HIV Integrase

Research Areas:  

Infection

Hydroxyisoquinoline-1,3(2H,4H)-dione (compound 6a) is a HIV-1 integrase (IN) and HIV-1 reverse transcriptase (RT) ribonuclease H (RNase H) inhibitor with an IC50 value of 6.32, 5.9 µM, respectively .
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Cat. No.: HY-N0457AR
CAS No.: 70831-56-0
Synonyms: (-)-Chicoric acid (Standard); trans-Caffeoyltartaric acid (Standard)
L-Chicoric Acid (Standard) is the analytical standard of L-Chicoric Acid. This product is intended for research and analytical applications. L-Chicoric Acid ((-)-Chicoric acid) is a dicaffeoyltartaric acid and a potent, selective and reversible HIV-1 integrase inhibitor with an IC50 of ~100 nM. L-Chicoric Acid inhibits HIV-1 replication in tissue culture .
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Cat. No.: HY-122229
CAS No.: 2219362-41-9
Target:  

HIV

Research Areas:  

Infection

GS-9822 is a potent antivira agent with nanomolar activity against wild-type HIV-1 viruses. GS-9822 potently inhibits the LEDGF/p75-integrase interaction with an IC50 of 0.07 μM. GS-9822 has high in vitro metabolic stability and favorable oral pharmacokinetic profiles with low systemic clearance in rats, dogs, and monkeys .
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Cat. No.: HY-14740S2
Synonyms: GS-9137-13C6 ; JTK-303-13C6 ; D06677-13C6
Elvitegravir- 13C6 (GS-9137- 13C6) is 13C labeled Elvitegravir. Elvitegravir (GS-9137; JTK-303; D06677) is an HIV integrase inhibitor for HIV-1IIIB, HIV-2EHO and HIV-2ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively.
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Cat. No.: HY-14740S1
Synonyms: GS-9137-d6; JTK-303-d6; D06677-d6
Elvitegravir-d6 (GS-9137-d6) is deuterium labeled Elvitegravir. Elvitegravir (GS-9137; JTK-303; D06677) is an HIV integrase inhibitor for HIV-1IIIB, HIV-2EHO and HIV-2ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively .
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Cat. No.: HY-10353AS
CAS No.: 1246816-98-7
Synonyms: MK 0518-d3 potassium
Raltegravir-d3 (potassium) is the deuterium labeled Raltegravir potassium. Raltegravir (MK 0518) potassium is a potent integrase (IN) inhibitor, used to treat HIV infection .
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Cat. No.: HY-N11288
CAS No.: 1015171-69-3
Methyl salvionolate A is a potent inhibitor of HIV-1. Methyl salvionolate A inhibits P24 antigen in HIV-1 infected MT-4 cell with an EC50 of 1.62 μg/ml. Methyl salvionolate A also inhibits HIV-1 reverse transcriptase, protease and integrase with IC50s of 50.58, 10.73 and 7.58 μg/ml, respectively .
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Cat. No.: HY-10353AR
CAS No.: 871038-72-1
Synonyms: MK 0518 potassium (Standard)
Research Areas:  

Infection Cancer

Raltegravir (potassium) (Standard) is the analytical standard of Raltegravir (potassium). This product is intended for research and analytical applications. Raltegravir (MK 0518) potassium is a potent integrase (IN) inhibitor, used to treat HIV infection.
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Cat. No.: HY-12210
CAS No.: 957889-73-5
Target:  

HIV Integrase

Research Areas:  

Infection

(S)-BI-1001 (Compound 11) is an active S-enantiomer of BI-1001. (S)-BI-1001 exhibits antiviral potency against HIV-1 integrase with an IC50 of 28 nM, an EC50 of 450 nM and a Kd of 4.7 μM .
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