130 Results for "

physiological functions

" in MedChemExpress (MCE) Product Catalog:
Products (130)

130 Results for "physiological functions" in MCE Product Catalog:

Cat. No.: HY-113443
CAS No.: 71774-10-2
Target:  

AP-1

Research Areas:  

Metabolic Disease

12(S)-HPETE is a 12-hydroxyeicosatetraenoic acid. 12(S)-HPETE has the function of regulating vascular tone. 12(S)-HPETE induces the expression of c-Fos and c-Jun protein and increases activating protein 1 (AP-1) activity in vascular smooth muscle cells.12(S)-HPETE may play a physiological role in vasomotor regulation through endothelium itself and crosstalk between blood cells and endothelium. 12(S)-HPETE can be used in the study of cerebrovascular tension .
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Cat. No.: HY-DY1068
CAS No.: 2360411-64-7
Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate (solution) is a low-toxicity azide reactive probe (NIR fluorescent dye) , for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
Solvent and concentration: DMSO: 10 mM
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Cat. No.: HY-A0129R
CAS No.: 51-74-1
Synonyms: Histamine diphosphate (Standard)
Histamine phosphate (Standard) is the analytical standard of Histamine phosphate (HY-A0129). This product is intended for research and analytical applications. Histamine phosphate is the agonist for histamine receptor and a vasodilator. Histamine phosphate is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine phosphate affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine phosphate can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
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Cat. No.: HY-B1204S4
Synonyms: Ergamine-15N3
Histamine- 15N3 is the 15N3-labeled Histamine (HY-B1204). Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
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Cat. No.: HY-121650
CAS No.: 53463-78-8
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

ADTN is a dopamine receptor agonist that has the activity of promoting dopamine neurotransmission. ADTN can be used to increase the release of neurotransmitters, thereby improving dopamine-related physiological functions. ADTN's potential applications include inhibiting mental illness and improving cognitive function .
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Cat. No.: HY-101677
CAS No.: 182798-83-0
Purity:  99.62%
Target:  

Drug Metabolite

Research Areas:  

Infection

cPrPMEDAP is an intermediate metabolite of GS-9219. cpr-PMEDAP functions as a proagent of the guanine nucleotide analog PMEG and has antiproliferative activity. cPrPMEDAP is negatively charged at physiologic pH and has poor permeability into the skin .
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Cat. No.: HY-P10687
Target:  

RXFP Receptor

Research Areas:  

Others

H3B10-27(13/17αF) is an excellent scaffold for further developing reagent candidates and an important tool for understanding the physiological functions of the neuropeptide G protein-coupled receptor RXFP3, and it's very stable in serum .
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Cat. No.: HY-P1245A
CAS No.: 2924824-03-1
Synonyms: Neuropeptide NPFF (human) acetate
Target:  

CRFR

Research Areas:  

Others

Neuropeptide SF (human) acetate augments paraventricular corticotrophin-releasing hormone (CRH) release and increases adrenocorticotropic hormone (ACTH) and corticosterone levels in the plasma. Neuropeptide SF (human) acetate play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH .
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Cat. No.: HY-155597
CAS No.: 716358-51-9
Target:  

NTPDase

h-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM). h-NTPDases8 is involved in a variety of physiological and pathological functions,such as thrombosis,diabetes,inflammation,and cancer .
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Cat. No.: HY-174540
Target:  

mRNA

Research Areas:  

Cancer

Human SERPINA1 mRNA encodes the human serpin family A member 1 (SERPINA1) protein, a serine protease inhibitor belonging to the serpin superfamily. SERPINA1’s major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).
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Cat. No.: HY-W923366
CAS No.: 119110-38-2
Synonyms: ETH 4030
Magnesium ionophore III (ETH 4030) is an ionophore that has the activity of regulating the intracellular magnesium concentration. Magnesium ionophore III can promote the permeability of cell membranes to magnesium ions and enhance cell functions and metabolic activities. Magnesium ionophore III is also used to study the importance of magnesium ions in biological processes and its effects on cell physiology.
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Cat. No.: HY-116557
CAS No.: 140652-99-9
Research Areas:  

Others

JCP-265 is a compound used for in vivo phenotypic screening of small molecule libraries, which has the activity of screening molecules that regulate cell function. JCP-265 uses molecular cell barcoding technology to directly screen small molecule libraries in vivo for studying complex physiological processes, such as screening compounds related to targets in pancreatic cancer metastasis seeding studies.
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Cat. No.: HY-E70523A
Synonyms: Valeryl-CoA sodium; Valeryl-coenzyme A sodium
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Pentanoyl coenzyme A (Valeryl-CoA) sodium is a short-chain fatty acyl-CoA that functions as an intermediate in mitochondrial β-oxidation and related metabolic pathways. Pentanoyl coenzyme A sodium results from the formal condensation of the thiol group of coenzyme A with the carboxy group of pentanoic acid. Pentanoyl coenzyme A sodium's levels can reflect changes in lipid metabolism under different physiological and pathological conditions. Pentanoyl coenzyme A sodium can be used for research on lipid metabolism .
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Cat. No.: HY-134658
CAS No.: 38232-01-8
Hentriacontanoic acid is a long-chain saturated fatty acid commonly found in various plant and animal tissues, especially in certain waxes and oils, such as beeswax and lanolin. Hentriacontanoic acid has unique chemical properties that make it an important ingredient in many industrial products, including cosmetics, candles and lubricants. It also has potential physiological roles in regulating lipid metabolism and protecting against oxidative stress, although its biological function is not fully understood.
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Cat. No.: HY-W779021
CAS No.: 41547-82-4
Synonyms: Adenine riboside-15N; D-Adenosine-15N
Adenosine- 15N (Adenine riboside- 15N) is 15N labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .
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Cat. No.: HY-143864
CAS No.: 2700209-37-4
Target:  

LPL Receptor

Research Areas:  

Inflammation/Immunology

S1PR1 agonist 1 is a potent agonist of S1PR1. Sphingosine-1-phosphate (S1P) is a cell membrane-derived lysophospholipid signalling molecule that exerts its physiological functions mainly by stimulating some members of the G protein-coupled receptor family. S1PR1 agonist 1 has the potential for the research of autoimmune diseases (extracted from patent WO2021175223A1, compound 22) .
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Cat. No.: HY-W989120
CAS No.: 29428-96-4
cis-6,9,12-Hexadecatrienoic acid is an important fatty acid with biological membrane fluidity and flexibility regulation activity. The multiple double bond structures of cis-6,9,12-Hexadecatrienoic acid help to improve the fluidity of cell membranes, thereby affecting cell molecular transport and signal transduction pathways. cis-6,9,12-Hexadecatrienoic acid plays a key role in cell physiological processes and promotes the normal function and interaction of cells.
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Cat. No.: HY-100481
CAS No.: 139088-45-2
Synonyms: RPR101048
Research Areas:  

Neurological Disease

RP 72540 is a selective CCK-B receptor antagonist, with IC50 values of 2.4, 1.2, and 3.8 nM for CCK-B receptors in the guinea pig cerebral cortex, rat cerebral cortex, and mouse brain, respectively. RP 72540 effectively inhibits CCK-8-induced neuronal firing and dose-dependently inhibits gastric acid secretion, making it potentially valuable in studies of acid secretion. RP 72540 is an important tool for investigating the physiological functions of CCK B receptors .
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Cat. No.: HY-165046
CAS No.: 5188-25-0
Synonyms: TG(18:2(9E,12E)/18:2(9E,12E)/18:2(9E,12E)); Trilinoelaidin
Research Areas:  

Others

1,2,3-Trilinoelaidoyl glycerol (TG(18:2(9E,12E)/18:2(9E,12E)/18:2(9E,12E))) is a compound that affects dietary triolein and has an effect on the fatty acid composition of rat organs, prostaglandin biosynthesis and platelet function. Different doses of intake have different effects on related physiological parameters of rats.
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Cat. No.: HY-17417AR
CAS No.: 465-65-6
Naloxone Standard is the analytical standard of Naloxone (HY-17417A). This product is intended for research and analytical applications. Naloxone is an opioid receptor antagonist. Naloxone attenuates spinal cord stimulation‑associated anti‑hyperalgesic effects, antagonizes physiologic effects of endogenous opioid peptides linked to central nervous system injury sequelae, functions as a pressor agent to induce modest elevations in mean arterial blood pressure, exerts neuroprotective effects to improve post‑traumatic neurologic motor function, blocks opioid receptor‑mediated amnesic pathways, enhances memory consolidation, reverses Adrenocorticotropic hormone (ACTH) (HY-106373)‑ and epinephrine‑induced amnesia, and potentiates the memory‑facilitatory effects of ACTH and epinephrine .
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