121 Results for "

catecholamines

" in MedChemExpress (MCE) Product Catalog:
Products (121)

121 Results for "catecholamines" in MCE Product Catalog:

Cat. No.: HY-B0158S
CAS No.: 40632-25-5
Synonyms: Cytosine β-D-riboside-d2; Cytosine-1-β-D-ribofuranoside-d2
Cytidine-d2 is the deuterium labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .
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Cat. No.: HY-N7142S1
CAS No.: 1392208-07-9
DL-Norepinephrine-d3 hydrochloride is the deuterium labeled DL-Norepinephrine hydrochloride. DL-Norepinephrine hydrochloride is an external racemic catecholamine neurotransmitter, which is an equal mixture of the left-handed (L-, with activity) and right-handed (D-, with very low or no activity) stereoisomers. DL-Norepinephrine hydrochloride after being labeled with tritium can be used as a tracer for the research on Parkinson's disease.
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Cat. No.: HY-106447
CAS No.: 72141-57-2
Losulazine is an orally active antihypertensive agent. Losulazine modulates acid phosphatase, 3β-hydroxysteroid dehydrogenase, and 17β-hydroxysteroid dehydrogenase activity. Losulazine can be used for the research of hypertension .
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Cat. No.: HY-33549R
CAS No.: 658-48-0
Synonyms: α-Methyl-p-tyrosine (Standard)
α-Methyl-p-tyrosine (Standard) is the analytical standard of α-Methyl-p-tyrosine. This product is intended for research and analytical applications. α-Methyl-p-tyrosine is a competitive inhibitor of tyrosine hydroxylase, which converts tyrosine into DOPA. α-Methyl-p-tyrosine is also an orally active inhibitor of catecholamine synthesis, inhibiting the hydroxylation of tyrosine into DOPA. α-Methyl-p-tyrosine can be used in research related to epilepsy, glaucoma, cancer, and other related diseases .
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Cat. No.: HY-113154
CAS No.: 2475-56-1
Synonyms: VLA
Target:  

Endogenous Metabolite

Research Areas:  

Others

Vanillactic acid (VLA) is a relevant biomarker associated with Aromatic L-amino acid decarboxylase (AADC) deficiency. AADC deficiency is a primary neurotransmitter defect of the biosynthesis of catecholamines and serotonin .
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Cat. No.: HY-B0158S5
CAS No.: 202406-79-9
Synonyms: Cytosine β-D-riboside-13C9,15N3; Cytosine-1-β-D-ribofuranoside-13C9,15N3
Cytidine- 13C9, 15N3 is the 13C and 15N labeled Cytidine . Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .
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Cat. No.: HY-W768207
CAS No.: 159496-15-8
Cytidine-1',2',3',4',5'- 13C5 is the 13C-labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .
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Cat. No.: HY-B0950
CAS No.: 1227-61-8
Synonyms: ANP-297
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Mefexamide (ANP-297) is a psychostimulant psychopharmaceutical and aryloxyacetic acid derivative antidepressant with dopaminergic activity. Mefexamide can be used for the research of depression .
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Cat. No.: HY-14280A
CAS No.: 1047659-02-8
Target:  

COMT

Research Areas:  

Neurological Disease Cancer

Entacapone sodium salt is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone sodium salt inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone sodium salt is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 µM). Entacapone sodium salt can be used for the research of Parkinson's disease . Entacapone sodium salt serves as as a inhibit of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders .
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Cat. No.: HY-150100
CAS No.: 9036-22-0
Synonyms: Tyrosine hydroxylase
Target:  

Tyrosine Hydroxylase

Research Areas:  

Neurological Disease

Tyrosine 3-monooxygenase (Tyrosine hydroxylase) is a rate-limiting enzyme in catecholamine biosynthesis and belongs to the family of aromatic amino acid hydroxylases. Tyrosine 3-monooxygenase catalyzes the initial and rate-limiting step in the biosynthetic pathway of catecholamines, including dopamine, noradrenaline, and adrenaline .
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Cat. No.: HY-B1231R
CAS No.: 543-15-7
Synonyms: RP-2831 hydrochloride (Standard)
Heptaminol (hydrochloride) (Standard) is the analytical standard of Heptaminol (hydrochloride). This product is intended for research and analytical applications. Heptaminol (RP-2831) hydrochloride is a vasoconstrictor used in the study of hypotension, especially orthostatic hypotension. Heptaminol is also a skin cancer proliferation inhibitor that inhibits immune inflammation induced by the tumor promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Heptaminol also acts as a sympathomimetic amine, exerting indirect sympathetic effects. Heptaminol is also an antagonist of catecholamine release and uptake and can increase intracellular free calcium levels .
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Cat. No.: HY-123449A
Purity:  99.93%
MK-761 TFA is an orally effective β2-adrenergic receptor antagonist. MK-761 TFA attenuates positive inotropic effects, reduces arterial pressure, enhances the contractility of papillary muscles in cat hearts, and exerts effects mediated by catecholamine release. MK-761 TFA can be used in the research of hypertension .
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Cat. No.: HY-123449
CAS No.: 65321-41-7
Purity:  99.56%
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

MK-761 free base is an orally effective β2-adrenergic receptor antagonist. MK-761 free base attenuates positive inotropic effects, reduces arterial pressure, enhances the contractility of papillary muscles in cat hearts, and exerts effects mediated by catecholamine release. MK-761 free base can be used in the research of hypertension .
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Cat. No.: HY-P0221A
Synonyms: Pituitary Adenylate Cyclase Activating Polypeptide 38 TFA
PACAP (1-38), human, ovine, rat TFA is a PAC1 receptor agonist. PACAP (1-38), human, ovine, rat TFA binds to PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2 with IC50s of 4 nM, 2 nM, and 1 nM, respectively. PACAP (1-38), human, ovine, rat TFA increases the α-secretase activity. PACAP (1-38), human, ovine, rat TFA elevates cytosolic Ca 2+, increases proliferation and increases phosphorylation of extracellular regulates kinase (ERK) and the epidermal growth factor receptor (EGFR). PACAP (1-38), human, ovine, rat TFA demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP (1-38), human, ovine, rat TFA can be used for neurotrophic and neuroprotective research .
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Cat. No.: HY-P3041
CAS No.: 133633-11-1
Target:  

Calcium Channel

Research Areas:  

Endocrinology

Chromostatin bovine is a chromogranin A (CGA) derivative peptide, which inhibits postassium or carbamoylcholine induced catecholamine release with an ID50 of 5 nM. Chromostatin bovine reduces calcium flux, enhances the desensitization process of the cholinergic-evoked secretory response and modulates the endocrine response associated with catecholamine .
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Cat. No.: HY-P5876
CAS No.: 154095-31-5
Synonyms: ProADM N20(bovine, porcine); PAMP-20(bovine, porcine)
Target:  

nAChR

Research Areas:  

Neurological Disease

Proadrenomedullin (N-20) (ProADM N20) (bovine, porcine) is a potent and noncompetitive hypotensive and catecholamine release-inhibitory peptide released from chromaffin cells. Proadrenomedullin (N-20) (bovine, porcine) inhibits catecholamine secretion with an IC50 of 350 nM in PC12 pheochromocytoma cells. Proadrenomedullin (N-20) (bovine, porcine) also blocks (EC50≈270 nM) nicotinic cholinergic agonist desensitization of catecholamine release, as well as desensitization of nicotinic signal transduction ( 22Na + uptake) .
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Cat. No.: HY-101416R
CAS No.: 1081-71-6
Synonyms: Vanylpyruvic acid (Standard)
Vanilpyruvic acid (Standard) is the analytical standard of Vanilpyruvic acid. This product is intended for research and analytical applications. Vanilpyruvic acid is a catecholamine metabolite and precursor to vanillactic acid.
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Cat. No.: HY-170738
CAS No.: 34200-97-0
Research Areas:  

Neurological Disease

Oudenone derivative-1 potassium is a derivative of Oudenone. Oudenone, a metabolite of the fungus, is a catecholamine biosynthesis and tyrosine hydroxylases inhibitor .
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Cat. No.: HY-121789
CAS No.: 302-33-0
Target:  

Cytochrome P450

Research Areas:  

Others

Proadifen is a compound that inhibits cytochrome P450 activity, which can change the excitability of catecholamine-secreting neurons in the brain and have different effects on neurons in different brain regions.
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Cat. No.: HY-118406
CAS No.: 524-83-4
Synonyms: Ponalid; UK 738
Target:  

mAChR

Research Areas:  

Neurological Disease

Ethybenztropine (Ponalid) is a muscarinic receptor blocker. Ethybenztropine is an anticholinergic and antihistaminergic agent .
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