658-48-0
Chemical Structure
Racemetirosine
Synonym(s): α-Methyl-p-tyrosine
- CAS No.: 658-48-0
- Formula:C10H13NO3
- Molecular Weight:195.22
IUPAC Name: 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid
InChIKey: NHTGHBARYWONDQ-UHFFFAOYSA-N
SMILES: O=C(C(C)(CC1=CC=C(C=C1)O)N)O
Biological Activity: Racemetirosine (α-Methyl-p-tyrosine) is a competitive inhibitor of tyrosine hydroxylase, which converts tyrosine into DOPA. Racemetirosine is also an orally active inhibitor of catecholamine synthesis, inhibiting the hydroxylation of tyrosine into DOPA. Racemetirosine can be used in research related to epilepsy, glaucoma, cancer, and other related diseases[1][2][3][4].
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Racemetirosine | 99.41% | Racemetirosine (α-Methyl-p-tyrosine) is a competitive inhibitor of tyrosine hydroxylase, which converts tyrosine into DOPA. Racemetirosine is also an orally active inhibitor of catecholamine synthesis, inhibiting the hydroxylation of tyrosine into DOPA. Racemetirosine can be used in research related to epilepsy, glaucoma, cancer, and other related diseases. | ||||||||||||||||||||
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Racemetirosine (Standard) | ≥98% | Racemetirosine (Standard) (α-Methyl-p-tyrosine (Standard)) is the analytical standard of Racemetirosine (HY-33549). This product is intended for research and analytical applications. Racemetirosine (α-Methyl-p-tyrosine) is a competitive inhibitor of tyrosine hydroxylase, which converts tyrosine into DOPA. Racemetirosine is also an orally active inhibitor of catecholamine synthesis, inhibiting the hydroxylation of tyrosine into DOPA. Racemetirosine can be used in research related to epilepsy, glaucoma, cancer, and other related diseases. | ||||||||||||||||||||
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DL-Racemetirosine-13C,d3 hydrochloride | DL-Metirosine-13C,d3 (hydrochloride) is deuterium labeled α-Methyl-p-tyrosine. | |||||||||||||||||||||
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Similarity Score 1.00
HY-W015007RMetyrosine (Standard) -
Similarity Score 0.89
HY-178277SL-Tyrosine-d1 -
Similarity Score 0.86
HY-121809DL-Methyldopa -
Similarity Score 0.86
HY-B0225Methyldopa -
Similarity Score 0.86
HY-W387035D-α-Methyl DOPA -
Similarity Score 0.85
HY-W016552(S)-2-Amino-2-methyl-3-phenylpropanoic acid -
Similarity Score 0.85
HY-W141831α-Methyl-DL-phenylalanine -
Similarity Score 0.83
HY-N0473S1L-Tyrosine-15N -
Similarity Score 0.83
HY-N0473S4L-Tyrosine-13C -
Explore the MedChemAI to find more analogs
References
- [1]. R N Brogden, et al. alpha-Methyl-p-tyrosine: a review of its pharmacology and clinical use. Drugs. 1981 Feb;21(2):81-9. [Content Brief]
- [2]. Abed WT. Differential effects of alpha-methyl-p-tyrosine and 6-hydroxydopamine on pentylenetetrazol seizures in mice. Pharmacol Biochem Behav. 1986 Nov;25(5):949-52. [Content Brief]
- [3]. Drago F, et al. alpha-Methyl-p-tyrosine inhibits latanoprost-induced melanogenesis in vitro. Exp Eye Res. 1999 Jan;68(1):85-90. [Content Brief]
- [4]. Jones NF, et al. Alpha-methyl-p-tyrosine in the management of phaeochromocytoma. Lancet. 1968 Nov 23;2(7578):1105-9. [Content Brief]
