Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
125 Results for "
oxidative processes
" in MedChemExpress (MCE) Product Catalog:
Products (125)
125 Results for "oxidative processes" in MCE Product Catalog:
Cat. No.: HY-B2035R
CAS No.: 51218-49-6
Target:
Reference Standards Herbicide Cytochrome P450 Interleukin Related Apoptosis Reactive Oxygen Species (ROS) Caspase MDM-2/p53 Environmental Pollutants
Research Areas:
Pretilachlor (Standard) is the analytical standard of Pretilachlor (HY-B2035). This product is intended for research and analytical applications. Pretilachlor is a chloroacetamide herbicide with biological activities including endocrine disruption, oxidative stress induction, apoptosis induction, and immunotoxicity. Pretilachlor exerts its effects by interfering with hormone metabolism, inducing oxidative stress, activating apoptotic pathways, and inhibiting immune functions. Pretilachlor upregulates the transcription of P53, Mdm2, and Bbc3, and increases the activities of Caspase3 and Caspase9; it upregulates the transcription of genes in the HPG/HPT axis and the activity of aromatase; it induces oxidative stress, elevates ROS levels, and upregulates CAT, SOD, and GPX. Pretilachlor downregulates the transcription of CXCL-C1C, IL-1β, and IL-8. Pretilachlor disrupts the normal physiological processes and embryonic development of fish, exhibiting significant toxicity. Pretilachlor can be used in studies related to weeding, environmental pollution, and behavioral toxicity in fish .
Cat. No.: HY-128525R
CAS No.: 28384-96-5
Category:
Target:
Research Areas:
MEG (Mercaptoethylguanidine) hemisulfate is a potent and selective inhibitor of the inducible NO synthase (iNOS), with EC50s of 11.5, 110, and 60 μM for iNOS, ecNOS, and bNOS respectively in tissue homogenates. MEG hemisulfate is also a potent scavenger of peroxynitrite and inhibits peroxynitrite-induced oxidative processes. MEG hemisulfate has a protective effect in many experimental models of inflammation, including ischemia/reperfusion injury, periodontitis, hemorrhagic shock, inflammatory bowel disease, and endotoxic and septic shock .
Cat. No.: HY-N2021AR
CAS No.: 164204-38-0
Category:
Cat. No.: HY-W040074
CAS No.: 23273-91-8
Synonyms: Diglycine hydrochloride hydrate; Gly-Gly (HCl H2O)
Cat. No.: HY-113466R
CAS No.: 75899-68-2
Synonyms: 4-HNE (Standard)
Cat. No.: HY-B0863S5
CAS No.: 2732154-65-1
Category:
Target:
Safrole oxide is a p53 modulator that upregulates the expression of the p53 tumor suppressor protein, linking cell cycle arrest to the apoptotic process. Safrole oxide induces apoptosis in lung cancer cells without triggering necrosis. Safrole oxide can be used in lung cancer-related research .
Cat. No.: HY-182438
CAS No.: 91456-99-4
Target:
Research Areas:
SDZ 51641 is an orally active fatty acid oxidation inhibitor. By reducing fatty acid oxidation, SDZ 51641 deprives the gluconeogenesis process of required energy and cofactors, thereby lowering blood glucose levels in diabetic models. SDZ 51641 can be used in diabetes research .
Cat. No.: HY-W714180
CAS No.: 27218-04-8
Target:
Research Areas:
Desmethyl-formamido-pirimicarb is an intermediate metabolite of Pirimicarb (HY-119419). Desmethyl-formamido-pirimicarb is detected in both Pirimicarb-exposed soil environments and advanced oxidation water treatment processes .
Cat. No.: HY-P2993B
Target:
Research Areas:
Isocitrate dehydrogenase (NAD+) , Bacteria (EC 1.1.1.41) is an enzyme that catalyzes the oxidative decarboxylation of Isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2. This is a two-step process, which involves oxidation of Isocitrate (a secondary alcohol) to oxalosuccinate (a ketone) , followed by the decarboxylation of the carboxyl group beta to the ketone, forming alpha-ketoglutarate.
Cat. No.: HY-L037
2,489 compounds
Oxidative stress is an imbalance of free radicals and antioxidants in the body, which can lead to cell and tissue damage. Oxidative stress can be responsible for the induction of several diseases, both chronic and degenerative, as well as speeding up body aging process and cause acute pathologies. Antioxidants are a class of compounds able to counteract oxidative stress and mitigate its effects on individuals’ health, gained enormous attention from the biomedical research community. Antioxidants have long been substantial and amenable therapeutic arsenals for multifarious diseases such as AD and cancer.
MCE Antioxidant Compound Library contains 2,489 compounds that act as antioxidants for high throughput screening (HTS) and high content screening (HCS). This library is a useful tool for discovery new antioxidants and oxidative stress research.
Cat. No.: HY-W750677
CAS No.: 19866-02-5
Category:
Target:
Cat. No.: HY-W127785S
CAS No.: 161562-43-2
Synonyms: N,N-Dimethyldodecylamine N-oxide-d31; Dodecyldimethylamine oxide-d31
Cat. No.: HY-176894
CAS No.: 141661-39-4
Research Areas:
Hemiacetylcarnitinium chloride is a inhibitor of fatty acid metabolism, specifically targeting carnitine palmitoyltransferase I (CPT I). Hemiacetylcarnitinium chloride disrupts the conversion of fatty acyl-CoA to fatty acyl carnitine, thereby blocking the subsequent oxidation of long-chain fatty acids and reducing the production of ATP required for energy-dependent cellular processes. Hemiacetylcarnitinium chloride can be used for the study of fatty acid metabolism .
Cat. No.: HY-L263
89 compounds
Energy metabolism is the most fundamental biochemical process in living organisms, encompassing glycolysis, the TCA cycle, oxidative phosphorylation, the pentose phosphate pathway, and fatty acid oxidation. These core pathways directly regulate cell survival, proliferation, differentiation, and apoptosis. Dysregulation of energy metabolism is closely linked to major diseases including cancer, diabetes, obesity, cardiovascular diseases, neurodegenerative disorders, and ischemia‑reperfusion injury. Targeting these metabolic pathways has become a frontier in drug discovery and mechanistic research.
The MCE Energy Metabolite Compound Library features 89 structurally defined small‑molecule compounds. It covers energy substrates, pathway intermediates, coenzymes and redox carriers, nucleotide derivatives, and microenvironmental modulators. This library is applicable to research areas including tumor metabolism, insulin resistance, mitochondrial dysfunction, oxidative stress, neuroprotection, and cardiometabolic diseases, providing a high‑quality tool for mechanistic studies, biomarker discovery, and high‑throughput drug screening.
Target:
Research Areas:
Diphenamid is a chemical compound that exhibits herbicide activity. Diphenamid acts by inhibiting the enzyme acetyl-CoA carboxylase. Diphenamid has shown resistance as a model for mimicking organic pollutants in wastewater treatment processes, especially in the presence of multiple anions. The degradation of diphenamid is significantly affected by certain inorganic ions, such as chromium (VI) and nitrogen oxides. Diphenamid shows changes in toxicity with longer treatment times, and the results of toxicity tests on selected algae indicate higher toxicity at 240 minutes of treatment .
Cat. No.: HY-187090
CAS No.: 69658-91-9
Synonyms: 3-NMPY
Research Areas:
3-N-Nitroso-N-methylaminopyridine is a non-carcinogenic, non-mutagenic arylalkyl nitrosamine isomer that serves as a substrate for enzymatic metabolic processes. 3-N-Nitroso-N-methylaminopyridine undergoes enzymatic denitrosation, enzymatic N-oxide formation, and limited oxidative demethylation to produce trace amounts of 3-hydroxypyridine. 3-N-Nitroso-N-methylaminopyridine directly induces gene mutations in E. coli, but its mutagenic potential is eliminated by the rodent liver S-100 fraction. 3-N-Nitroso-N-methylaminopyridine shows no carcinogenicity in rats and no mutagenicity in the Ames test . 3-NMPY can be used in studies related to the metabolism and carcinogenic mechanisms of nitrosamine compounds in vitro and in vivo .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
