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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
326 Results for "
Calcium/Sodium Channel Blocker
" in MedChemExpress (MCE) Product Catalog:
Products (326)
326 Results for "Calcium/Sodium Channel Blocker" in MCE Product Catalog:
Cat. No.: HY-136482
CAS No.: 79925-38-5
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Nemadipine B is a calcium channel blocker and an EGL-19 antagonist. Nemadipine B induces Egl, Vab and Gro phenotypes in Caenorhabditis elegans .
Cat. No.: HY-L117
226 compounds
Calcium channel blockers (CCBs), also called calcium antagonists are compounds that slow the movement of calcium (Ca2+) through calcium channels into the cells of the heart and blood vessel walls. Calcium causes the heart and arteries to squeeze more strongly. By blocking calcium, calcium channel blockers allow blood vessels to relax and open. So calcium channel blockers are usually used to lower blood pressure, relieve chest pain (angina) and control an irregular heartbeat.
MCE supplies a unique collection of 226 calcium channel blockers and antagonists, all of which have the identified inhibitory effect on calcium channel. MCE Calcium Channel Blocker Library is a useful tool for discovery of antihypertensive drugs and cardiovascular disease research.
Cat. No.: HY-101674
CAS No.: 57010-32-9
Synonyms: Ro 11-1781
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Tiapamil hydrochloride is a calcium channel blocker.
Cat. No.: HY-U00135
CAS No.: 136941-70-3
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Calcium channel-modulator-1 is an orally active calcium channel modulator that blocks aortic contraction with an IC50 of 0.8 μM. Calcium channel-modulator-1 can be used for the study of cardiovascular conditions .
Cat. No.: HY-B0317C
CAS No.: 246852-12-0
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Amlodipine mesylate, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine mesylate can be used for the research of high blood pressure and cancer .
Cat. No.: HY-B0317S1
CAS No.: 1185246-14-3
Cat. No.: HY-B0317AS1
Cat. No.: HY-B0612E
CAS No.: 184866-29-3
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(S)-Lercanidipine hydrochloride is the S-enantiomer of Lercanidipine hydrochloride. (S)-lercanidipine hydrochloride is a potent calcium channel blocker .
Cat. No.: HY-B0317S
CAS No.: 1185246-15-4
Cat. No.: HY-W415121
CAS No.: 73360-54-0
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Bupivacaine hydrochloride monohydrate is a NMDA receptor inhibitor. Bupivacaine hydrochloride monohydrate can block sodium, L-calcium, and potassium channels. Bupivacaine hydrochloride monohydrate potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine hydrochloride monohydrate can be used for the research of chronic pain .
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Mebeverine hydrochloride, a β-phenylethylamine derivative, is a musculotropic agent that potently blocks intestinal peristalsis. Mebeverine directly blocks voltage-operated sodium channels and inhibits intracellular calcium accumulation .
Cat. No.: HY-135478
CAS No.: 325819-97-4
Synonyms: NCC1048
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LY393615 (NCC1048) is a novel neuronal Ca 2+ (calcium channel) and Na + channel (sodium channel) blocker with IC50s of 1.9 μΜ and 5.2 μΜ for α1A and α1B calcium channel subunits. LY393615 has good brain penetration and neuroprotective effects in models of in cerebral ischemia that can be used for neurological disease research .
Cat. No.: HY-135478A
CAS No.: 774528-12-0
Synonyms: NCC1048 free base
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LY393615 (NCC1048) free base is a novel neuronal Ca 2+ (calcium channel) and Na + channel (sodium channel) blocker with IC50s of 1.9 μΜ and 5.2 μΜ for α1A and α1B calcium channel subunits. LY393615 free base has good brain penetration and neuroprotective effects in models of in cerebral ischemia that can be used for neurological disease research .
Cat. No.: HY-167168
CAS No.: 722455-09-6
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(S)-Azelnidipine is a calcium channel (Calcium Channel) blocker and the S-isomer of Azelnidipine, with potential for use in cardiovascular disease research .
Cat. No.: HY-101621
CAS No.: 108700-03-4
Synonyms: GR53992B; GX1296B
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Teludipine is a lipophilic calcium channel blocker.
Cat. No.: HY-101740
CAS No.: 138383-07-0
Synonyms: SQ31765; SQ 31765
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SQ-31765 is a benzazepine calcium channel blocker.
Cat. No.: HY-U00218
CAS No.: 99254-95-2
Synonyms: RWJ26240
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McN5691 is a voltage-sensitive calcium channel blocker.
Cat. No.: HY-B0317AS
CAS No.: 2714486-25-4
Synonyms: YC-93-d3
Synonyms: (S)-YC-93 free base
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(S)-Nicardipine ((S)-YC-93 free base) is the less active S enantiomer of Nicardipine. Nicardipine is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
