325819-97-4
Chemical Structure
LY393615
Synonym(s): NCC1048
- CAS No.: 325819-97-4
- Formula:C21H26ClF2NO
- Molecular Weight:381.89
IUPAC Name: N-((5,5-bis(4-fluorophenyl)tetrahydrofuran-2-yl)methyl)butan-1-amine hydrochloride
InChIKey: GBBGQGHWUPHIOP-UHFFFAOYSA-N
SMILES: FC1=CC=C(C2(C3=CC=C(F)C=C3)CCC(CNCCCC)O2)C=C1.[H]Cl
Biological Activity: LY393615 (NCC1048) is a novel neuronal Ca2+ (calcium channel) and Na + channel (sodium channel) blocker with IC50s of 1.9 μΜ and 5.2 μΜ for α1A and α1B calcium channel subunits. LY393615 has good brain penetration and neuroprotective effects in models of in cerebral ischemia that can be used for neurological disease research[1].
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LY393615 | LY393615 (NCC1048) is a novel neuronal Ca2+ (calcium channel) and Na + channel (sodium channel) blocker with IC50s of 1.9 μΜ and 5.2 μΜ for α1A and α1B calcium channel subunits. LY393615 has good brain penetration and neuroprotective effects in models of in cerebral ischemia that can be used for neurological disease research. | |||||||||||||||||||||
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Keywords
