774528-12-0
774528-12-0
Chemical Structure
LY393615 free base
Synonym(s): NCC1048 free base
- CAS No.: 774528-12-0
- Formula:C21H25F2NO
- Molecular Weight:345.43
InChIKey: UEIJJWIYTDBDNO-UHFFFAOYSA-N
SMILES: FC1=CC=C(C2(C3=CC=C(C=C3)F)OC(CC2)CNCCCC)C=C1
Biological Activity: LY393615 (NCC1048) free base is a novel neuronal Ca2+ (calcium channel) and Na + channel (sodium channel) blocker with IC50s of 1.9 μΜ and 5.2 μΜ for α1A and α1B calcium channel subunits. LY393615 free base has good brain penetration and neuroprotective effects in models of in cerebral ischemia that can be used for neurological disease research[1].
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LY393615 free base | LY393615 (NCC1048) free base is a novel neuronal Ca2+ (calcium channel) and Na + channel (sodium channel) blocker with IC50s of 1.9 μΜ and 5.2 μΜ for α1A and α1B calcium channel subunits. LY393615 free base has good brain penetration and neuroprotective effects in models of in cerebral ischemia that can be used for neurological disease research. | |||||||||||||||||||||
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References
Keywords
