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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
174 Results for "
Kinetics
" in MedChemExpress (MCE) Product Catalog:
Products (174)
174 Results for "Kinetics" in MCE Product Catalog:
Cat. No.: HY-147691
CAS No.: 2476764-11-9
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MPO-IN-5 (compound 1) is a potent, irreversible MPO (myeloperoxidase) inhibitor. MPO-IN-5 inhibits MPO peroxidation and hERG binding, with IC50 values of 0.22 and 2.8 μM, respectively. MPO-IN-5 shows rapid kinetics of inhibition, with enzyme inactivation rate (kinact/Ki) of 23000 M −1s −1 .
Cat. No.: HY-173535
Synonyms: TNP-β-L-Guanosine 5'-triphosphate tetrasodium
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TNP-β-L-GTP (TNP-β-L-Guanosine 5'-triphosphate) tetrasodium is a fluorescent GTP mimetic that can be used to study the binding kinetics and affinity of GTP-binding proteins (such as G proteins and GTPases). TNP-β-L-GTP tetrasodium carries a TNP fluorophore, which changes fluorescence intensity upon protein binding, allowing for quantitative analysis .
Cat. No.: HY-116138
CAS No.: 137515-05-0
RG-14467 is an epidermal growth factor receptor tyrosine kinase inhibitor with activity that inhibits enzyme activity. RG-14467 has similar inhibition kinetics to Lavendustin-A, with a dissociation constant of 3.4μM for the initial rapidly formed complex and an overall dissociation constant estimated to be less than or equal to 30nM, and is a partially competitive inhibitor for ATP.
Cat. No.: HY-147964
CAS No.: 735273-33-3
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α-Glucosidase-IN-9 (compound 7) is a potent α-glucosidase inhibitor, with an IC50 of 55.6 μM. α-Glucosidase-IN-9 can be used for type II diabetes research .
Cat. No.: HY-147965
CAS No.: 2586282-68-8
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α-Glucosidase-IN-10 (compound 13) is a potent α-glucosidase inhibitor, with an IC50 of 92.7 μM. α-Glucosidase-IN-10 can be used for type II diabetes research .
Cat. No.: HY-126182
CAS No.: 42399-40-6
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Deacetyldiltiazem is a metabolite with coronary vasodilator activity. Deacetyldiltiazem is present in the plasma of individuals taking Diltiazem. The deacetylase activity of deacetyldiltiazem is mainly catalyzed by the rat Ces2a enzyme. In vitro experiments of deacetyldiltiazem showed that its Km value was similar to that of rat liver microsomes, showing efficient deacetylase activity. The study of deacetyldiltiazem helps to understand the differences in the metabolic kinetics of compounds between different species .
Cat. No.: HY-P5368
CAS No.: 1802084-26-9
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Cat. No.: HY-E70532
CAS No.: 37278-25-4
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Ribonuclease T2 (animal free) (EC 4.6.1.19) is a biocatalyst and a key enzyme in new biocatalyst technologies. Enzyme engineering aims to enhance enzyme reaction kinetics, substrate selectivity and activity under adverse conditions (e.g., low or high pH). By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible. This product does not contain animal-derived ingredients .
Cat. No.: HY-137411
CAS No.: 40757-80-0
Synonyms: (E/Z)-Linoleoyl Coenzyme A; (E/Z)-9,12-Octadecadienoyl Coenzyme A
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(E/Z)-Linoleoyl-CoA is a substrate used to study the specificity and kinetics of acyl-CoA. (E/Z)-Linoleoyl-CoA has the ability to replace substrates, and its specificity can be changed by amino acid substitution, thereby affecting the reaction with different desaturases. The study of (E/Z)-Linoleoyl-CoA helps to understand the substrate specificity of mammalian front-end fatty acid desaturases and provides support for the efficient production of value-added fatty acids .
Cat. No.: HY-P3118
CAS No.: 1325307-57-0
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Cat. No.: HY-D3394
CAS No.: 1331918-67-2
Cat. No.: HY-101693AR
CAS No.: 98326-33-1
Synonyms: MCI 154 hydrochloride (Standard)
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Senazodan (hydrochloride) (Standard) is the analytical standard of Senazodan (hydrochloride) (HY-101693A). This product is intended for research and analytical applications. Senazodan (MCI 154) (hydrochloride), as a Ca2+ sensitiser, shows inhibition effect on PDE III .
Cat. No.: HY-184367
CAS No.: 41149-01-3
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Ac-L-Asp-pNA is a non-substrate peptidyl p-nitroaniline. Ac-L-Asp-pNA is not hydrolyzed by recombinant mature Paenibacillus protease I or its single-point mutants. Ac-L-Asp-pNA can be used in studies related to enzyme activity and kinetics .
Cat. No.: HY-186240
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Fluoxakalner is a selective Kv7.2/7.3 channel opener with an EC50 of 0.36 μM. Fluoxakalner accelerates the activation kinetics of Kv7.2/7.3 channels and produces anti-nociceptive effects. Fluoxakalner is applicable for pain research .
Cat. No.: HY-E70321
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Cefradine acylase (Immobilized) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
Cat. No.: HY-N16305
CAS No.: 3091879-60-3
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Cyanine 7 DBCO chloride is a click chemistry reagent containing an cycloalkynes group. Cyanine 7 DBCO chloride is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability (Ex/Em = 745/785 nm) .
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Betaine homocysteine S-methyltransferase is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
Cat. No.: HY-E70351
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Trypsin-Chymotrypsin 1:1 is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
