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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
177 Results for "
parasitic
" in MedChemExpress (MCE) Product Catalog:
Products (177)
177 Results for "parasitic" in MCE Product Catalog:
Cat. No.: HY-L082
673 compounds
A parasite is an organism that lives on or in a host organism and gets its food from or at the expense of its host. Parasites of humans include protozoans, helminths, and ecto-parasites (organisms that live on the external surface of a host). They are responsible for many diseases and are transmitted to their hosts most often through the ingestion of contaminated food, water or through the bite of an arthropod (e.g., a fly or tick), which can act as an intermediate host and as a vector. Parasitic diseases of humans are a major global health problem causing significant morbidity and mortality, especially in developing countries. Each year there are hundreds of millions of people infected with disease-causing parasites, particularly in tropical and subtropical regions of the world, resulting in an estimated one million deaths. Therefore, there is a dire need of novel anti-parasitic drugs.
MCE has a unique collection of 673 compounds with validated anti-parasitic activity which offer researchers an opportunity to screen novel anti-parasitic targets.
Cat. No.: HY-187615
CAS No.: 160825-48-9
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AM4299 A is a thiol protease inhibitor with IC50 values of 73, 390 and 88 nM against Cathepsin B, Cathepsin L and Papain, respectively. AM4299 A shows low toxicity and favorable biosafety in mice. AM4299 A can be used in studies related to osteoporosis and parasitic diseases .
Cat. No.: HY-12641B
CAS No.: 26155-20-4
Pyrantel hydrochloride is an orally active antiparasitic agent. Pyrantel hydrochloride induces spastic paralysis in parasites via actions on neural and muscular cholinergic receptors as a nicotinic acetylcholine receptor (nAChR) agonist. Pyrantel hydrochloride eliminates both immature and mature endoparasites in horses. Pyrantel hydrochloride can be used in research related to parasitic infections .
Cat. No.: HY-W727209
CAS No.: 1254304-22-7
Fluazaindolizine is a fluorinated nematicide. Fluazaindolizine induces mortality in second-stage juveniles (J2) of Meloidogyne incognita and Tylenchulus semipenetrans in vitro. Fluazaindolizine impacts plant-parasitic nematode parasitism. Fluazaindolizine can be used for the research of plant-parasitic nematode infestation .
Cat. No.: HY-136897
CAS No.: 65195-54-2
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Cat. No.: HY-180343
CAS No.: 1795429-46-7
FFK29 is a synthetic class II histone deacetylase inhibitor (HDACi). FFK29 can potently inhibit the growth and encystation of Acanthamoeba. FFK29 can be studied in research on protozoan and parasitic diseases .
Cat. No.: HY-174771
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Human CCL11 mRNA encodes the human C-C motif chemokine ligand 11 (CCL11) protein, a member of the CC subfamily. CCL11 is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
Cat. No.: HY-W783593
CAS No.: 65195-51-9
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Cat. No.: HY-N21718
CAS No.: 1140269-83-5
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Leguminosae Terpenoids Ketones, Aldehydes, Acids Biancaea decapetala (Roth) O. Deg. Diterpenoids Plants
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Cat. No.: HY-P11862
CAS No.: 2097822-76-7
Synonyms: MBJ-0173
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Cat. No.: HY-W011517
CAS No.: 146-78-1
Synonyms: 2FA
Cat. No.: HY-W011517R
CAS No.: 146-78-1
Synonyms: 2FA (Standard)
Cat. No.: HY-B0497A
CAS No.: 40321-86-6
Synonyms: BAY2353 sodium
Target:
Niclosamide (BAY2353) sodium is an orally active antihelminthic agent used in parasitic infection research . Niclosamide sodium is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells . Niclosamide sodium has biological activities against cancer, and inhibits DNA replication in Vero E6 cells .
Cat. No.: HY-B0497B
CAS No.: 73360-56-2
Synonyms: BAY2353 monohydrate
Target:
Niclosamide (BAY2353) monohydrate is an orally active antihelminthic agent used in parasitic infection research . Niclosamide monohydrate is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells . Niclosamide monohydrate has biological activities against cancer, and inhibits DNA replication in Vero E6 cells .
Cat. No.: HY-W973644
CAS No.: 147104-27-6
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LY-266500 is a succinyl CoA synthetase (SCS) specific inhibitor. LY-266500 has inhibitory effects on various parasites, such as Trypanosoma brucei brucei (IC50 =0.6 μM) and Leishmania donovani (IC50 =2.86 μM). LY-266500 can be used for research on parasitic infections .
Cat. No.: HY-160075
CAS No.: 164931-16-2
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NMT-IN-2 is an inhibitor of human N-myristoyltransferase 1/2 (NMT1/NMT2) that inhibits their catalytic activity, with IC50 values of 348.9 nM and 512.8 nM, respectively. NMT-IN-2 can be used for research on NMT-related diseases such as cancer, viral infections, and parasitic diseases .
Cat. No.: HY-17596S
CAS No.: 1325559-20-3
Cat. No.: HY-N16426
CAS No.: 1532554-02-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
