1. Anti-infection
  2. Parasite
  3. Fluazaindolizine

Fluazaindolizine is a fluorinated nematicide. Fluazaindolizine induces mortality in second-stage juveniles (J2) of Meloidogyne incognita and Tylenchulus semipenetrans in vitro. Fluazaindolizine impacts plant-parasitic nematode parasitism. Fluazaindolizine can be used for the research of plant-parasitic nematode infestation.

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Fluazaindolizine

Fluazaindolizine Chemical Structure

CAS No. : 1254304-22-7

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Description

Fluazaindolizine is a fluorinated nematicide. Fluazaindolizine induces mortality in second-stage juveniles (J2) of Meloidogyne incognita and Tylenchulus semipenetrans in vitro. Fluazaindolizine impacts plant-parasitic nematode parasitism. Fluazaindolizine can be used for the research of plant-parasitic nematode infestation[1].

In Vitro

Fluazaindolizine (100-600 mg/L; 24-72 h) potently induces mortality in Meloidogyne incognita J2 in vitro, with an LC50 of 177.1 mg/L[1].
Fluazaindolizine (100-1600 mg/L; 24-72 h) induces mortality in Tylenchulus semipenetrans J2 in vitro, with an LC50 of 355.2 mg/L[1].
Fluazaindolizine (125-1000 mg/L; 24-72 h) weakly induces mortality in Pratylenchus brachyurus mixed life stages in vitro, with an LC50 of 1187.5 mg/L[1].
Fluazaindolizine (100-1600 mg/L; 24-72 h) weakly induces mortality in Heterodera schachtii J2 in vitro, with a 72-h LC50 of 1019.3 mg/L[1].
Fluazaindolizine (100-500 mg/L; 3-6 days) reduces hatching rate in Meloidogyne incognita J2 hatched from exposed egg masses and reduces hatching rate only at the highest tested concentration of 400 and 500 mg/L[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Meloidogyne incognita J2
Concentration: 100, 200, 300, 400, 500 mg/L
Incubation Time: 3 and 6 days
Result: Increasd mortality time- and concertration dependently.
Reduced hatching rate at 400 and 500 mg/L.
Molecular Weight

468.23

Formula

C16H10Cl2F3N3O4S

CAS No.
SMILES

O=C(NS(=O)(=O)C1=CC(OC)=CC=C1Cl)C=2N=C3C(Cl)=CC(=CN3C2)C(F)(F)F

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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References
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Fluazaindolizine Related Classifications

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Fluazaindolizine
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HY-W727209
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