Pyrantel hydrochloride
Pyrantel hydrochloride is an orally active antiparasitic agent. Pyrantel hydrochloride induces spastic paralysis in parasites via actions on neural and muscular cholinergic receptors as a nicotinic acetylcholine receptor (nAChR) agonist. Pyrantel hydrochloride eliminates both immature and mature endoparasites in horses. Pyrantel hydrochloride can be used in research related to parasitic infections.
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- No. CAS: 26155-20-4
- Fòrmula: C11H15ClN2S
- Peso molecular:242.77
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Pyrantel hydrochloride acts as an L-subtype cholinergic receptor agonist in Ascaris suum body-flap muscle, with a pEC50 of 7.24[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 26155-20-4
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Peso molecular 242.77
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Fòrmula C11H15ClN2S
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SMILES
CN1C(/C=C/C2=CC=CS2)=NCCC1.Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Tritten L, et al. In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections. PLoS neglected tropical diseases. 2011 Dec;5(12):e1457. [Content Brief]
[2]. Martin RJ, et al. Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris. International journal for parasitology. 2004 Aug;34(9):1083-90. [Content Brief]
[3]. Lyons ET, et al. Critical test of three salts of pyrantel against internal parasites of the horse. Am J Vet Res. 1974 Dec;35(12):1515-22. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pyrantel hydrochloride Related Classifications
HY-12641B Related Classifications
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