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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
169 Results for "
Pyrazole
" in MedChemExpress (MCE) Product Catalog:
Products (169)
169 Results for "Pyrazole" in MCE Product Catalog:
Cat. No.: HY-W002461
CAS No.: 2458-26-6
Cat. No.: HY-182458
CAS No.: 949560-05-8
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GNE-203 is a heterobicyclic pyrazole compound and receptor tyrosine kinase inhibitor targeting c-Met.GNE-203 can be used for the research of cancer .
Cat. No.: HY-10179R
CAS No.: 827318-97-8
Synonyms: PHA-739358 (Standard)
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Danusertib (Standard) is the analytical standard of Danusertib. This product is intended for research and analytical applications. Danusertib is a pyrrolo-pyrazole and aurora kinase inhibitor with IC50 of 13, 79, and 61 nM for Aurora A, B, and C, respectively.
EGFR-IN-86 (compound 4i) is an EGFR inhibitor (IC50: 1.5 nM) with high activity against glioblastoma. EGFR-IN-86 induces apoptosis and arrests the U87 cell cycle in the G2/M phase .
Synonyms: SD-06
Domaines de recherche:
SD 0006 (SD-06) is an orally active, selective, ATP-competitive and potent diaryl pyrazole inhibitor of p38α MAP kinase, with an IC50 of 110 nM for p38α .
PK7088 is a pyrazole and a specific peptide. PK7088 supports the reactivation of mutant p53 by converting it to a form exhibiting wild-type properties. PK7088 exhibit anticancer activity in cancer research .
Cat. No.: HY-133726R
CAS No.: 581809-46-3
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Bixafen (Standard) is the analytical standard of Bixafen. This product is intended for research and analytical applications. Bixafen, a member of the pyrazole class of fungicides, serves as a broad-spectrum agent for controlling pathogens in cereal crops by functioning as a succinate dehydrogenase inhibitor.
Cat. No.: HY-148481
CAS No.: 2755995-01-6
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USP7-IN-10 (compound 1) is a potent ubiquitin-specific protease 7 (USP7) inhibitor, with an IC50 of 13.39 nM .
Cat. No.: HY-151618
CAS No.: 2750233-50-0
Antitumor agent-79 shows good antiproliferative activities against hepatocellular carcinoma and breast cancer cells with IC50 values of 0.7-7.9 μM. Antitumor agent-79 induces cancer cells apoptosis and shows in vivo antitumor effects. Antitumor agent-79 can be used for the research of cancer .
Cat. No.: HY-145568A
CAS No.: 2340299-00-3
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Feniralstat (compound 30) hydrochloride, a pyrazole derivative, is a potent kallikrein inhibitor with an IC50 of 6.7 nM for Human plasma kallikrein (pKal). Feniralstat has no inhibition on Human KLKl, Human FXIa, Human Factor Xlla (all IC50>40 μM) .
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Pyroxasulfone is a broad-spectrum pyrazole Herbicide. Pyroxasulfone is effective against a variety of annual grass weeds and some broadleaf weeds. Pyroxasulfone causes reduced plant height, decreased above-ground dry weight and yield loss in pinto beans and red Mexican beans .
Cat. No.: HY-111108R
CAS No.: 1964515-43-2
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LDH-IN-1 (Standard) is the analytical standard of LDH-IN-1 (HY-111108). This product is intended for research and analytical applications. LDH-IN-1 is a novel pyrazole-based inhibitor of human lactate dehydrogenase (LDH) with IC50s of 32 and 27 nM for LDHA and LDHB, respectively.
Cat. No.: HY-W654191
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Betazole (Ametazole) dihydrochloride, a pyrazole analogue of histamine, is an orally active H2 receptor agonist. Betazole dihydrochloride induces gastric acid secretion, and causes an immediate and significant increase in common bile duct pressure. Betazole dihydrochloride has been used as a diagnostic agent known as histalog, for investigating gastric acid secretory capacity .
Cat. No.: HY-147751
CAS No.: 1965244-85-2
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APJ receptor agonist 6 (compound 9) is a potent APJ (apelin receptor) agonist, with Ki of 1.3 μM. APJ receptor agonist 6 has EC50 values of 0.070 , 0.097, and 0.063 μM for calcium, cAMP, and β-arrestin, respectively .
Cat. No.: HY-170358
CAS No.: 861382-34-5
Antileishmanial agent-31 (Compound p1) is a pyrazole derivative. Antileishmanial agent-31 has anti-leishmania activity with an IC50 of 35.53 μg/mL. In addition, Antileishmanial agent-31 has high stability. Antileishmanial agent-31 can be used for anti-leishmaniasis research .
Cat. No.: HY-189228
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HPPD-IN-15 is a potent HPPD inhibitor with an IC50 of 52 nM (Arabidopsis thaliana). HPPD-IN-15 inhibits HPPD through chelation of Fe 2+ by the pyrazole group, π-π stacking, and insertion of the benzyl group into a hydrophobic pocket. HPPD-IN-15 can be used for herbicide development research .
Cat. No.: HY-11087R
CAS No.: 271576-80-8
Synonyms: SD-06 (Standard)
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SD 0006 (Standard) is the analytical standard of SD 0006 (HY-11087). This product is intended for research and analytical applications. SD 0006 (SD-06) is an orally active, selective, ATP-competitive and potent diaryl pyrazole inhibitor of p38α MAP Kinase, with an IC50 of 110 nM for p38α .
Cat. No.: HY-158985
CAS No.: 2267315-06-8
Amino-PEG3-2G degrader-1 (compound ) is a conjugate of a PEG Linker and a pyrazole-linked FBnG tag for ubiquitin-proteasome system (UPS) induction. Amino-PEG3-2G degrader-1 can be used to synthesize autophagy-targeting chimeras (AUTACs) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
