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United States

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製品番号: HY-189228

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HPPD-IN-15

HPPD-IN-15 is a potent HPPD inhibitor with an IC₅₀ of 52 nM (Arabidopsis thaliana). HPPD-IN-15 inhibits HPPD through chelation of Fe²⁺ by the pyrazole group, π-π stacking, and insertion of the benzyl group into a hydrophobic pocket. HPPD-IN-15 can be used for herbicide development research.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₂₁H₁₈ClN₅O₅
分子量:455.85

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

HPPD-IN-15 構造式

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IC₅₀ & Target

^[1]

AtHPPD

52 nM (IC₅₀)

体外実験

HPPD-IN-15 (compound II-19) exhibits extremely potent competitive inhibitory activity against AtHPPD enzyme, with an IC₅₀ of 52 nM^[1].
HPPD-IN-15 (30-120 g a.i./ha; 24 days) exhibits moderate post-emergence herbicidal activity in greenhouse weeds (such as ECHCG, SETVI, DIGSA, etc.)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

分子量 455.85
分子式 C₂₁H₁₈ClN₅O₅
SMILES

CC1=NN(C(O)=C1C(C2=CC=C3C(N(C(N3C)=O)CC4=CC=CC([N+]([O-])=O)=C4)=C2Cl)=O)C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Li B, et al. Discovery of Pyrazole-Benzimidazolin-2-One Derivatives as 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors. Journal of agricultural and food chemistry. 2026 Aug 19;74(32):25119-25128.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

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分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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