1965244-85-2

APJ receptor agonist 6 Chemical Structure
1965244-85-2

Chemical Structure

APJ receptor agonist 6

  • CAS No.: 1965244-85-2
  • Formula:C29H34FN3O5
  • Molecular Weight:523.60

IUPAC Name: (S)-5-cyclohexyl-3-(5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)-1H-pyrazole-3-carboxamido)pentanoic acid

InChIKey: CPULTTQFADDSLA-NRFANRHFSA-N

SMILES: COC1=CC=CC(OC)=C1C2=CC(C(N[C@H](CC(O)=O)CCC3CCCCC3)=O)=NN2C4=CC=C(C=C4)F

Biological Activity: APJ receptor agonist 6 (compound 9) is a potent APJ (apelin receptor) agonist, with Ki of 1.3 μM. APJ receptor agonist 6 has EC50 values of 0.070 , 0.097, and 0.063 μM for calcium, cAMP, and β-arrestin, respectively[1].

Cat. No. Product Name Purity Description Pricing
HY-147751 		APJ receptor agonist 6 APJ receptor agonist 6 (compound 9) is a potent APJ (apelin receptor) agonist, with Ki of 1.3 μM. APJ receptor agonist 6 has EC50 values of 0.070 , 0.097, and 0.063 μM for calcium, cAMP, and β-arrestin, respectively.
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