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Referencia número: HY-143296

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SphK1-IN-1

SphK1-IN-1 (compound 48) is a SphK1 inhibitor with effective antitumor activity. SphK1-IN-1 inhibits SphK1 ATPase with an IC₅₀ value of 4.02 μM. SphK1-IN-1 can be used for the research of cancer.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₂₂H₂₂N₆O₂
Peso molecular:402.45

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

SphK1-IN-1 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

IC₅₀ & Target

SphK1

Ver todos los productos específicos de isoformas SphK :

SphK1
SphK2

In Vitro

SphK1-IN-1 (0-25 μM) shows inhibitory effect to SphK1 ATPase with an IC₅₀ value of 4.02 μM ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Peso molecular 402.45
Fòrmula C₂₂H₂₂N₆O₂
SMILES

CC1=NN(C(N2CCCCC2)=C1C3=NC4=CC([N+]([O-])=O)=CC=C4N3)C5=CC=CC=C5
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. A. Galal, et al. Design and synthesis of new pyrazolylbenzimidazoles as sphingosine kinase-1 inhibitors. (2021) 1614–1634.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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SphK1-IN-1

Ver todos los productos específicos de isoformas SphK

Actividad biológica

Descripciòn

IC50 & Target

In Vitro

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

SphK1-IN-1 Related Classifications

HY-143296 Related Classifications

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