3055550-22-3
3055550-22-3
Chemical Structure
EGFR-IN-86
- CAS No.: 3055550-22-3
- Formula:C20H21N7O2S
- Molecular Weight:423.49
InChIKey: WDJPMSIMYPBJIU-UHFFFAOYSA-N
SMILES: CC(C=C1)=NN1C2=NC(NC3=C(S(=O)(N4CCC4)=O)C=CC=C3)=C5C(N(C)C=C5)=N2
Biological Activity: EGFR-IN-86 (compound 4i) is an EGFR inhibitor (IC50: 1.5 nM) with high activity against glioblastoma. EGFR-IN-86 induces apoptosis and arrests the U87 cell cycle in the G2/M phase[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
EGFR-IN-86 | 99.92% | EGFR-IN-86 (compound 4i) is an EGFR inhibitor (IC50: 1.5 nM) with high activity against glioblastoma. EGFR-IN-86 induces apoptosis and arrests the U87 cell cycle in the G2/M phase. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
