![(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc](https://file.medchemexpress.com/product_pic/hy-163226.gif "Click to View (1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
(1R,3R)-isomer
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "(1R,3R)-isomer" in MCE Product Catalog:
18
18 Publications Verification
Cat. No.: HY-P7114
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RSPO1; R-Spondin Homolog (Xenopus Laevis); R-Spondin 1; R-Spondin Homolog; Roof Plate-Specific Spondin-1; CRISTIN3; R-Spondin-1; HRspo1; FLJ40906; RSPO; RSPONDIN
Species:
Human
Source:
CHO
3
3 Cited Publications
Synonyms: (-)-trans-ML-SI3
Target:
Research Areas:
(1R,2R)-ML-SI3 is an isomer of ML-SI3 and a potent inhibitor of three isoforms of TRPML. (1R,2R)-ML-SI3 inhibits TRPMLs with IC50s of 1.6 μM (TRPML1), 2.3 μM (TRPML2), and 12.5 μM (TRPML3), respectively [1].
3
3 Cited Publications
Cat. No.: HY-32337
CAS No.: 57333-96-7
Synonyms: 1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3
Target:
Research Areas:
Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) can promote normal bone growth by regulating calcium ions. Tacalcitol inhibits cancer cell proliferation and migration. Tacalcitol can be used in the research of inflammation, cancer, and skin diseases [1] [3] .
3
3 Cited Publications
Target:
Research Areas:
(1R,3R)-RSL3 is an isomer of RSL3 (HY-100218A). RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells [1].
3
1
1 Cited Publications
Cat. No.: HY-P72784
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RSPO1; R-Spondin Homolog (Xenopus Laevis); R-Spondin 1; R-Spondin Homolog; Roof Plate-Specific Spondin-1; CRISTIN3; R-Spondin-1; HRspo1; FLJ40906; RSPO; RSPONDIN
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P700255
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RSPO1; R-Spondin Homolog (Xenopus Laevis); R-Spondin 1; R-Spondin Homolog; Roof Plate-Specific Spondin-1; CRISTIN3; R-Spondin-1; HRspo1; FLJ40906; RSPO; RSPONDIN
Species:
Mouse
Source:
E. coli
Cat. No.: HY-W006202
CAS No.: 261165-05-3
Synonyms: (1S,3R)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid
Target:
Research Areas:
Boc-(1S,3R)-3-aminocyclopentanecarboxylic acid ((1S,3R)-3-[(tert-butoxycarbonyl)amino]cyclopentanecarboxylic acid) is an intermediate used in chemical synthesis.
Cat. No.: HY-W063971
CAS No.: 1423769-08-7
Target:
Research Areas:
(1R,2R)-2-(Pyridin-3-yl)cyclopropane-1-carboxylic acid is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-108501
CAS No.: 208706-12-1
Target:
Research Areas:
(1R,1'S,3'R/1R,1'R,3'S)-L-054,264 is a selective non-peptide human somatostatin receptor subtype 2 (sst2) agonist. (1R,1'S,3'R/1R,1'R,3'S)-L-054,264 can be used in the study of retinal neuromodulation [1] .
Cat. No.: HY-13623C
CAS No.: 188399-46-4
Synonyms: (1R,3S,4R)-ent-BMS200475; (1R,3S,4R)-ent-SQ34676
(1R,3S,4R)-ent-Entecavir ((1R,3S,4R)-ent-BMS200475; (1R,3S,4R)-ent-SQ34676) can be used to synthesize PROTAC targets to degrade deoxyribonucleic acid (DNA) polymerase [1].
Target:
Research Areas:
(2R,3R)-E1R (Compound 2b) is an enantiomer of E1R. (2R,3R)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders [1].
Target:
Research Areas:
(1R,3R)-Ferroptosis inducer-1 is an isomer of Ferroptosis inducer-1 (HY-145595). (1R,3R)-Ferroptosis inducer-1 (compound BX-3a) is a Ferroptosis inducer with antitumor potential [1].
Cat. No.: HY-W034099
CAS No.: 1124175-25-2
Target:
Research Areas:
(1R,3R)-3-Hydroxycyclopentane carboxylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
Target:
Research Areas:
(2R,3S)-E1R (Compound 2c) is an enantiomer of E1R. (2R,3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders [1].
Cat. No.: HY-172514
CAS No.: 1185502-97-9
Target:
Research Areas:
(1R,2S,3R)-Aprepitant (Compound ent-4) is a competitive human neurokinin-1 (NK-1) receptor antagonist. (1R,2S,3R)-Aprepitant is promising for research of cancers and postoperative nausea and vomiting [1].
Cat. No.: HY-163226
Research Areas:
(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
Cat. No.: HY-W998338
CAS No.: 1338812-52-4
Target:
Research Areas:
(1R,3R)-3-Amino-2,2,4,4-tetramethylcyclobutan-1-ol phosphate is a PROTAC linker that can be used in the synthesis of PROTACs.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
