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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
(rel)-R-63373-d8
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "(rel)-R-63373-d8" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: rel-Cianidanol; rel-Catechuic acid
Category:
Cardiovascular Disease Neurological Disease Plants Camellia sinensis (L.) O. Ktze. Infection Phenols Polyphenols Disease Research Fields Inflammation/Immunology Theaceae
Target:
Synonyms: rel-eFT226
rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex .
Synonyms: rel-Cianidanol (Standard); rel-Catechuic acid (Standard)
Target:
Cat. No.: HY-W710914A
CAS No.: 219915-69-2
Target:
Research Areas:
rel-HDMP 28 hydrochloride (Compound 2g) is a methylphenidate analogue that binds selectively to SERT (Ki = 105 nM)[1].
Cat. No.: HY-B0511S1
CAS No.: 1217850-77-5
Synonyms: rel-Vitamin B7-d4; rel-Vitamin H-d4; rel-D-Biotin-d4
Cat. No.: HY-17371A
CAS No.: 63121-00-6
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Research Areas:
(rel)-Oxaliplatin is a DNA synthesis inhibitor. (rel)-Oxaliplatin causes DNA crosslinking damage, prevents DNA replication and transcription and induces apoptosis. (rel)-Oxaliplatin can be used for cancer research .
Cat. No.: HY-14690B
CAS No.: 1227675-51-5
Synonyms: rel-SCH 39166 hydrobromide
Target:
Research Areas:
rel-Ecopipam (rel-SCH 39166) (Compound 6b) hydrobromide is a D1 receptor antagonist (Ki: 1.30 nM) .
Cat. No.: HY-122359A
CAS No.: 31477-60-8
Synonyms: rel-L-Centchroman; Ormeloxifene
Research Areas:
rel-Levormeloxifene (rel-L-Centchroman) is the relative configuration of Levormeloxifene (HY-122359). rel-Levormeloxifene is a selective estrogen receptor modulator (SERM). rel-Levormeloxifene inhibits proliferation of leukemia cells with IC50 about 7 μM, arrests cell cycle at G0/G1 phase, and induces apoptosis. rel-Levormeloxifene induces differentation of myelogenesis leukemia, and enhances ROS production in K562 cells .
Cat. No.: HY-122495
CAS No.: 73625-62-4
Synonyms: rel-LY 171555 dihydrochloride; rel-LY 141865 dihydrochloride
Target:
Research Areas:
rel-Quinpirole (rel-LY 171555) dihydrochloride, an ergot compound, is a selective dopamine (DA) D2 receptor agonist. rel-Quinpirole dihydrochloride can be used for research on neurological diseases .
Cat. No.: HY-18941B
CAS No.: 176027-90-0
Synonyms: (rel)-LY354740; (rel)-Eglumetad
Target:
Research Areas:
(rel)-Eglumegad ((rel)-LY354740) is a relative configuration of Eglumegad (HY-18941). Eglumegad is a highly potent and selective group II (mGlu2/3) receptor agonist with EC50s of 5 and 24 nM for transfected human mGlu2 and mGlu3 receptors, respectively .
Cat. No.: HY-10121D
CAS No.: 1261398-77-9
Synonyms: rel-Org 5222 hydrochloride
Research Areas:
rel-Asenapine (rel-Org 5222) hydrochloride is a relative configuration of Asenapine hydrochloride (HY-16567). Asenapine (Org 5222) hydrochloride, an atypical antipsychotic, is an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4) and histamine receptors (pKi: 8.2-9.0). Asenapine hydrochloride can be used in the research of schizophrenia and bipolar disorder .
Cat. No.: HY-117283
CAS No.: 89544-10-5
Synonyms: rel-RP 52891
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rel-Aprikalim (rel-RP 52891) is the relative configuration of Aprikalim (HY-121183). Aprikalim (RP 52891), a potassium channel opener (KCO), activates ATP-sensitive K + (KATP) channels in guinea pig ventricular myocytes .
Cat. No.: HY-124874
CAS No.: 195966-93-9
Synonyms: (rel)-Aspergillimide; (rel)-VM55598
Category:
Target:
Cat. No.: HY-13047A
CAS No.: 110691-49-1
Synonyms: rel-Dexmecamylamine hydrochloride; rel-TC-5214 hydrochloride
Target:
Research Areas:
rel-S-(+)-Mecamylamine hydrochloride is a known antihypertensive drug .
Cat. No.: HY-106899A
CAS No.: 143445-03-8
Synonyms: (rel)-L-680573
Research Areas:
(rel)-MK 287 ((rel)-L-680573) is a relative configuration of MK 287. MK 287 is a potent, selective and orally active antagonist of platelet-activating factor receptor (PAFR). MK 287 can inhibit [3H]C18-PAF binding to human platelet, polymorphonuclear leukocyte (PMN) and lung membranes with K1 values of 6.1, 3.2, and 5.49 nM, respectively. MK 287 can inhibit PAF-induced aggregation of platelets in plasma or gel-filtered platelets and elastase release from PMNs with ED50 values of 56, 1.5 and 4.4 nM. MK 287 can be used for the research of cardiovascular disease, such as thrombosis .
Cat. No.: HY-14879D
CAS No.: 396731-20-7
Synonyms: rel-NXL-104; rel-AVE1330A
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Research Areas:
rel-Avibactam sodium (rel-NXL-104) is an isomer of Avibactam (HY-14879). Avibactam is a β-lactamase inhibitor with an IC50 of 8 nM against TEM-1 β-lactamase and an IC50 of 80 nM against P99 β-lactamase. Avibactam exhibits no significant intrinsic antibacterial activity when used alone. Avibactam restores the activity of Ceftazidime (HY-B0593) against β-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa. Avibactam does not enhance the activity of Ceftazidime against Acinetobacter spp., Burkholderia spp., or most anaerobic Gram-negative bacilli. Avibactam is used in research related to Gram-negative bacterial infections .
Cat. No.: HY-77493
CAS No.: 905853-99-8
Synonyms: (rel)-ARQ 197; (rel)-(3R,4R)-ARQ 198
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Research Areas:
(rel)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. (rel)-Tivantinib has two novel targets, GSK3α and GSK3β, which play an important role in the cellular mechanism of non-small cell lung cancer (NSCLC) .
Cat. No.: HY-109092A
CAS No.: 2730989-98-5
Synonyms: rel-LIK066
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Research Areas:
rel-Licogliflozin is a relative configuration of Licogliflozin (HY-109092). Licogliflozin is a sodium glucose cotransporter (SGLT1 and SGLT2) inhibitor .
Cat. No.: HY-12650A
CAS No.: 1138244-97-9
Synonyms: (rel)-DS5565
Target:
Research Areas:
(rel)-Mirogabalin ((rel)-DS5565) is a voltage-dependent calcium channel inhibitor that acts on the α2δ-1 subunit .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
