1. Cell Cycle/DNA Damage
    Anti-infection
    Apoptosis
  2. Eukaryotic Initiation Factor (eIF)
    SARS-CoV
    Apoptosis
  3. rel-Zotatifin

rel-Zotatifin (Synonyms: rel-eFT226)

Cat. No.: HY-112163A
Handling Instructions

rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex.

For research use only. We do not sell to patients.

rel-Zotatifin Chemical Structure

rel-Zotatifin Chemical Structure

CAS No. : 2098191-54-7

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1 mg USD 650 In-stock
Estimated Time of Arrival: December 31
5 mg USD 1850 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex[1].

Molecular Weight

487.55

Formula

C₂₈H₂₉N₃O₅

CAS No.

2098191-54-7

SMILES

N#CC1=CC=C([[email protected]@]2(O3)[[email protected]@](C4=C3C=C(OC)N=C4OC)(O)[[email protected]](O)[[email protected]](CN(C)C)[[email protected]]2C5=CC=CC=C5)C=C1.[Relative stereochemistry]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

rel-Zotatifinrel-eFT226Eukaryotic Initiation Factor (eIF)SARS-CoVApoptosisSARS coronavirusInhibitorinhibitorinhibit

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rel-Zotatifin
Cat. No.:
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