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Cat. No.: HY-14690B

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rel-Ecopipam hydrobromide

(Synonyms: rel-SCH 39166 hydrobromide)

rel-Ecopipam (rel-SCH 39166) (Compound 6b) hydrobromide is a D1 receptor antagonist (K_i: 1.30 nM).

For research use only. We do not sell to patients.

CAS No.: 1227675-51-5
Formula: C₁₉H₂₁BrClNO
Molecular Weight:394.73

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

rel-Ecopipam hydrobromide Chemical Structure

CAS No.: 1227675-51-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

rel-Ecopipam (rel-SCH 39166) (Compound 6b) hydrobromide is a D1 receptor antagonist (K_i: 1.30 nM)^[1].

IC₅₀ & Target

D1 receptor^[1]

All Dopamine Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	EC₅₀	12.6 μM Compound: Ecopipam	Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysis Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysis	[PMID: 20966043]
HepG2	EC₅₀	4 μM Compound: Ecopipam	Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis	[PMID: 20966043]

Chemical Information

CAS No. 1227675-51-5
Molecular Weight 394.73
Formula C₁₉H₂₁BrClNO
SMILES

CN1[C@]2([H])[C@@](C3=CC=CC=C3CC2)([H])C4=CC(O)=C(Cl)C=C4CC1.Br
Synonyms

rel-SCH 39166 hydrobromide
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Clark AH, et al. Assessment of dopamine D₁ receptor affinity and efficacy of three tetracyclic conformationally-restricted analogs of SKF38393. Bioorg Med Chem. 2011 Sep 15;19(18):5420-31. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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rel-Ecopipam hydrobromide

High-Throughput Bioactive Compound Library

All Dopamine Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

rel-Ecopipam hydrobromide Related Classifications

HY-14690B Related Classifications