72 Results for "

β-estradiol

" in MedChemExpress (MCE) Product Catalog:
Products (72)

72 Results for "β-estradiol" in MCE Product Catalog:

141
141 Publications Verification
Cat. No.: HY-B0141
CAS No.: 50-28-2
Synonyms: β-estradiol; E2; 17β-estradiol; 17β-Oestradiol
Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .
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141
141 Publications Verification
Cat. No.: HY-B0141C
CAS No.: 35380-71-3
Synonyms: β-estradiol hemihydrate; 17β-estradiol hemihydrate; 17β-Oestradiol hemihydrate
Estradiol (β-Estradiol) hemihydrate is a steroid hormone and the major female sex hormone. Estradiol (β-Estradiol) hemihydrate can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol (β-Estradiol) hemihydrate can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .
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33
33 Cited Publications
Cat. No.: HY-12033
CAS No.: 362-07-2
Purity:  99.76%
Synonyms: 2-ME2; NSC-659853
2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .
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22
22 Cited Publications
Cat. No.: HY-B1192
CAS No.: 50-50-0
Synonyms: β-estradiol 3-benzoate; 17β-estradiol 3-benzoate
Estradiol benzoate (β-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice .
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17
17 Cited Publications
Cat. No.: HY-103454
CAS No.: 911295-24-4
Purity:  99.54%
Research Areas:  

Endocrinology Cancer

MPP dihydrochloride is a potent and selective ER (estrogen receptor) modulator. MPP dihydrochloride induces significant apoptosis in the endometrial cancer and oLE cell lines. MPP dihydrochloride reverses the positive effects of beta-estradiol. MPP dihydrochloride has mixed agonist/antagonist action on murine uterine ERalpha in vivo .
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17
17 Cited Publications
Cat. No.: HY-103454B
CAS No.: 2863676-89-3
Purity:  99.28%
Research Areas:  

Endocrinology Cancer

MPP hydrochloride is a potent and selective ER (estrogen receptor) modulator. MPP hydrochloride induces significant apoptosis in the endometrial cancer and oLE cell lines. MPP hydrochloride reverses the the positive effects of beta-estradiol. MPP hydrochloride has mixed agonist/antagonist action on murine uterine ERalpha in vivo .
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3
3 Cited Publications
Cat. No.: HY-B0141S1
CAS No.: 66789-03-5
Synonyms: β-estradiol-d4; 17β-estradiol-d4; 17β-Oestradiol-d4
Estradiol-d4 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .
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2
2 Cited Publications
Cat. No.: HY-B0141R
CAS No.: 50-28-2
Synonyms: β-estradiol (Standard); E2 (Standard); 17β-estradiol (Standard); 17β-Oestradiol (Standard)
Estradiol (Standard) is the analytical standard of Estradiol. This product is intended for research and analytical applications. Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .
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2
2 Cited Publications
Cat. No.: HY-111832
CAS No.: 79886-50-3
Purity:  99.08%
Synonyms: TeGG
1,2,3,6-Tetragalloylglucose (TEgG) is a competitive inhibitor of UDP-glucuronyltransferase UGT1A1, targeting the competitive substrate binding site of UGT1A1. 1,2,3,6-Tetragalloylglucose inhibits UGT1A1-mediated β-estradiol 3-glucuronidation and SN-38 glucuronidation with IC50 of 6.01 μM and 4.31 μM, respectively, and binds to UGT1A1 with Ki of 3.55 μM. 1,2,3,6-Tetragalloylglucose also induces tumor cell apoptosis, inhibit cell proliferation, activates caspase-3 and induces DNA fragmentation in HL-60 cells. 1,2,3,6-Tetragalloylglucose also inhibits HIV integrase and reverse transcriptase, and inhibits HCV protease .
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2
2 Cited Publications
Cat. No.: HY-124489
CAS No.: 362-05-0
Purity:  ≥97.0%
2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity .
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2
2 Cited Publications
Cat. No.: HY-141672
CAS No.: 4999-79-5
Purity:  ≥99.0%
Synonyms: 17β-estradiol 3-sulfate sodium
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .
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2
2 Cited Publications
Cat. No.: HY-131404
CAS No.: 6466-43-9
Purity:  98.51%
Target:  

Estrogen Receptor/ERR

Research Areas:  

Cancer

TPBM is a potent estrogen receptor α (ERα) inhibitor with an IC50 value of 9 μM for 17β-estradiol (E2)-ERα. TPBM reduces E2·ERα recruitment to an endogenous estrogen-responsive gene. TPBM inhibits E2-dependent growth of ERα-positive cancer cells (IC50=5 μM). TPBM is not toxic to cells and does not affect estrogen-independent cell growth .
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1
1 Cited Publications
Cat. No.: HY-B0708
CAS No.: 1743-60-8
Synonyms: 1,3,5(10)-Estratriene-3,17β-diol 17-acetate
β-Estradiol 17-acetate (1,3,5(10)-Estratriene-3,17β-diol 17-acetate) is a long-acting endogenous estrogen precursor and also a cell viability and proliferation enhancer. β-Estradiol 17-acetate promotes the adhesion and proliferation of freshly isolated and revived female-derived human brain microvascular endothelial cells, and reverses the decreased viability of revived male-derived human brain microvascular endothelial cells. β-Estradiol 17-acetate exerts the microvascular protective effect of estrogen, enabling non-tumor human brain microvascular endothelial cells to be cultured in vitro for 2 months after cryopreservation. β-Estradiol 17-acetate is biotransformed into β-estradiol via hydrolase action in the in vitro skin of humans, hairless dogs, rats and hairless mice .
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1
1 Cited Publications
Cat. No.: HY-N10403
CAS No.: 5976-61-4
Synonyms: 4-Hydroxy-17β-estradiol
4-Hydroxyestradiol (4-Hydroxy-17β-estradiol) is an endogenous metabolite of Estradiol (HY-B0141). 4-Hydroxyestradiol is carcinogenic and shows mutagenic activity in breast epithelial cells. 4-Hydroxyestradiol inhibits the binding of Estradiol to the estrogen receptor in a competitive manner, with a Ki of 0.48 nM .
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1
1 Cited Publications
Cat. No.: HY-129583
CAS No.: 596093-98-0
Purity:  99.87%
Lepidiline A exhibits cytotoxic activity against HL-60 cells with an IC50 value of 32.3 μM. Lepidiline A targets HSD17B1 activity, increases the bioconversion efficiency of sex hormones (including the conversion of estrogen into 17β-estradiol and 4-androsten-3,7-dione into testosterone), thereby improving the reproductive capacity of fruit flies. .
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Cat. No.: HY-B0672
CAS No.: 979-32-8
Synonyms: β-estradiol 17-valerate
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology Cancer

Estradiol valerate (β-Estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.
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Cat. No.: HY-B0141S2
CAS No.: 221093-45-4
Synonyms: β-estradiol-d5; 17β-estradiol-d5; 17β-Oestradiol-d5
Estradiol-d5 is deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .
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Cat. No.: HY-B0672R
CAS No.: 979-32-8
Synonyms: β-estradiol 17-valerate (Standard)
Estradiol valerianate (Standard) is the analytical standard of Estradiol valerianate. This product is intended for research and analytical applications. Estradiol valerate (β-Estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.
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Cat. No.: HY-B0141S
CAS No.: 79037-37-9
Synonyms: β-estradiol-d3; 17β-estradiol-d3; 17β-Oestradiol-d3
Estradiol-d3 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
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Cat. No.: HY-148586
CAS No.: 7698-93-3
Purity:  98.83%
Target:  

Drug Derivative

Research Areas:  

Others

β-Estradiol 17-hemisuccinate is a synthetic derivative of estradiol (HY-B0141) .
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