123 Results for "

1,25-Dihydroxyvitamin D3-d3

" in MedChemExpress (MCE) Product Catalog:
Products (123)

123 Results for "1,25-Dihydroxyvitamin D3-d3" in MCE Product Catalog:

77
77 Publications Verification
Cat. No.: HY-10002
CAS No.: 32222-06-3
Purity:  99.94%
Synonyms: 1,25-Dihydroxyvitamin d3
Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
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17
17 Cited Publications
Cat. No.: HY-17365
CAS No.: 79517-01-4
Synonyms: SMS 201-995 acetate
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
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5
5 Cited Publications
Cat. No.: HY-A0020
CAS No.: 104121-92-8
Synonyms: ED-71; 2-(3-hydroxypropoxy)-1,25-Dihydroxyvitamin d3
Eldecalcitol (ED-71) is an orally active vitamin D3 analogue, inhibits bone resorption and increases bone mineral density. Eldecalcitol (ED-71) displays anti-tumor effect and inhibits cell proliferation, migration and induces apoptosis by suppressing GPx-1 .
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2
2 Cited Publications
Cat. No.: HY-136390
CAS No.: 1386162-69-1
Purity:  99.50%
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

ML417 is a selective and brain penetrant D3 dopamine receptor (D3R) agonist, with an EC50 of 38 nM. ML417 potently promotes D3R-mediated β-arrestin translocation, G protein mediated signaling, and pERK phosphorylation with minimal effects on other GPCR-mediated signaling. ML417 exhibits neuroprotection against toxin-induced neurodegeneration of dopaminergic neurons .
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1
1 Cited Publications
Cat. No.: HY-141412
CAS No.: 80731-10-8
Purity:  ≥98.0%
Synonyms: 3-Phospho-D-glyceric acid disodium
D-(-)-3-Phosphoglyceric acid (3-Phospho-D-glyceric acid) disodium is an important intermediate in the enzyme-catalyzed glycolysis process. D-(-)-3-Phosphoglyceric acid disodium competitively inhibits yeast enolase (enolase). D-(-)-3-Phosphoglyceric acid disodium can regulate the activity of phosphoglycerate dehydrogenase (PHGDH) to modulate p53 protein and apoptosis .
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1
1 Cited Publications
Cat. No.: HY-105055
CAS No.: 77327-05-0
Purity:  99.95%
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
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1
1 Cited Publications
Cat. No.: HY-158285
Purity:  ≥95.0%
25-OH Vitamin D3/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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1
1 Cited Publications
Cat. No.: HY-P73543
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: VDR; Vitamin D Receptor; NR1I1; Nuclear Receptor Subfamily 1 Group I Member 1; 1,25-Dihydroxyvitamin d3 Receptor; Vitamin d3 Receptor; PPP1R163; Vitamin D (1,25-Dihydroxyvitamin d3) Receptor; Protein Phosphatase 1, Regulatory Subunit 163; 1,25-Dihydroxyvi
Species:  
Human
Source:  
Sf9 insect cells
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1
1 Cited Publications
Cat. No.: HY-P81203
Synonyms: Vitamin d3 receptor; 125 Dihydroxyvitamin d3 receptor; 1 antibody 1,25-@Dihydroxyvitamin d3 receptor; 125 Dihydroxyvitamin d3 receptor; 25-Dihydroxyvitamin d3 receptor; NR1I1; Nuclear receptor subfamily 1 group I member 1; VDR; VDR_HUMAN; Vitamin D (1,25- Dihydroxyvitamin d3) receptor; Vitamin D hormone receptor; Vitamin D receptor; Vitamin d3 receptor,

Host:  

Rabbit

Application:  

IHC-P, IHC-F, ICC/IF

Reactivity:  

Human, Rat

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1
1 Cited Publications
Cat. No.: HY-10219S
CAS No.: 392711-19-2
Purity:  ≥93.0%
Synonyms: Sirolimus-d3; AY-22989-d3; NSC 226080-d3
Rapamycin-d3 (Sirolimus-d3; AY-22989-d3; NSC 226080-d3) is the deuterated-labeled Rapamycin (HY-10219). Rapamycin (Sirolimus; AY 22989) is a potent and specific blood-brain barrier-transmissible mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin is a molecular glue that binds FKBP12 and mTOR proteins together, thereby inhibiting mTOR kinase activity. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .
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1
1 Cited Publications
Cat. No.: HY-B0113S
CAS No.: 922731-01-9
Synonyms: H 16868-d3
Omeprazole-d3 (H 16868-d3) is deuterium labeled Omeprazole. Omeprazole (H 16868) is an orally active H +,K +-ATPase inhibitor and a proton pump inhibitor. Omeprazole competitively inhibits CYP2C19, CYP3A4, and CYP2C9 activity. Omeprazole inhibits gastric acid secretion and can be used for acid-related gastrointestinal disorders. Omeprazole inhibits pancreatic cancer cell proliferation, induces apoptosis, autophagosome accumulation (elevated LC3-I and LC3-II levels), oxidative stress, and cytogenetic imbalance, modulates lysosomal transport, reduces inflammatory cytokines. Omeprazole alters small intestinal morphology and magnesium absorption, and induces gastric mucosa morphologic changes. Omeprazole aslo has neuroprotective and antibacterial effects .
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Cat. No.: HY-15398S3
CAS No.: 80666-48-4
Purity:  98.45%
Synonyms: Cholecalciferol-d3; Colecalciferol-d3
Vitamin D3-d3 is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
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Cat. No.: HY-125586
CAS No.: 21150-22-1
Purity:  ≥96.0%
Research Areas:  

Cancer

β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
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Cat. No.: HY-N0666S8
CAS No.: 3842-25-9
L-Aspartic acid-d3 is the d3-labeled L-Aspartic acid (HY-N0666). L-Aspartic acid is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid has no independent analgesic activity. L-Aspartic acid can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid promotes burst firing of central neurons. L-Aspartic acid can be used in studies related to cerebral ischemia and epilepsy .
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Cat. No.: HY-76915
CAS No.: 40013-87-4
24, 25-Dihydroxy VD3 is a compound closely related to 1,25-dihydroxyvitamin D3 and is the active form of vitamin D3 .
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Cat. No.: HY-10002R
CAS No.: 32222-06-3
Synonyms: 1,25-Dihydroxyvitamin d3 (Standard)
Calcitriol (Standard) is the analytical standard of Calcitriol. This product is intended for research and analytical applications. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
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Cat. No.: HY-P4821
CAS No.: 83139-29-1
Research Areas:  

Metabolic Disease Cancer

PTH (1-34) amide human is a type 1 PTH/PTHrP receptor agonist. PTH (1-34) amide human activates adenylate cyclase and phospholipase C pathways, thereby mediating mineral ion homeostasis and bone metabolism regulation. PTH (1-34) amide human increases serum calcium, decreases serum phosphorus, regulates renal excretion, while inducing the inhibition of endogenous PTH (1-84) and the increase of 1,25-dihydroxyvitamin D2 and bone resorption. PTH (1-34) amide human stimulates phosphatidylcholine hydrolysis via phospholipase D mediation, and its hypercalcemic effect is inhibited by human PTH-(7-84). PTH (1-34) amide human can be used in the research of diseases related to humoral hypercalcemia of malignancy .
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Cat. No.: HY-W041895S1
CAS No.: 96927-56-9
DL-Glutamic acid-d3 is the d3-labeled DL-Glutamic acid (HY-W041895). DL-Glutamic acid is a racemic amino acid mixture and an antibacterial agent. DL-Glutamic acid reduces RNA and DNA levels, with a more significant effect on RNA. DL-Glutamic acid inhibits cell division of Rhodospirillum rubrum .
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Cat. No.: HY-10002S
Purity:  ≥97.0%
Synonyms: 1,25-Dihydroxyvitamin d3-13C3
Calcitriol- 13C3 is the 13C-labeled Calcitriol. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
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Cat. No.: HY-124867
CAS No.: 662164-09-2
Purity:  99.49%
Target:  

TSH Receptor

Research Areas:  

Endocrinology

D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 by direct TSHR activation and potentiates TSH-mediated preosteoblast differentiation in vitro .
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