14 Results for "

2-oleoylglycerol

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "2-oleoylglycerol" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W011121
CAS No.: 3443-84-3
Synonyms: 2-OG
2-Oleoylglycerol (2-OG) is a lipid found in the diet. It is a GPR119 agonist, with an EC50 value of 2.5 μM in activating hGPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol enhances the inflammatory response of macrophages and promotes fibrosis by activating the GPR119/TAK1/NF-κB/TGF-β1 signaling pathway. It also stimulates glucagon-like peptide 1 (GLP-1) secretion in vivo. 2-Oleoylglycerol is expected to be used in the research of non-alcoholic steatohepatitis (NASH) [2] .
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1 Cited Publications
Cat. No.: HY-N2512
CAS No.: 589-68-4
1-Monomyristin acts as an insecticide, enzyme inhibitor, antibacterial and antifungal agent, with an IC50 of 18 μM against rat FAAH and an IC50 of 32 μM against rat MAGL. 1-Monomyristin inhibits 2-oleoylglycerol hydrolysis via MAGL. 1-Monomyristin suppresses the growth of Staphylococcus aureus, Aggregatibacter actinomycetemcomitans and Candida albicans. 1-Monomyristin is lethal to brine shrimp . 1-Monomyristin exhibits marginal cytotoxicity against prostate cancer cells. 1-Monomyristin is applicable to research related to bacterial infections, fungal infections, renal cancer, prostate adenocarcinoma and pancreatic cancer [2] .
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Cat. No.: HY-W743570
CAS No.: 2929-07-9
Target:  

Drug Derivative

Research Areas:  

Others

2-Oleoylglycerol ether is an acylglycerol.
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Cat. No.: HY-172083
CAS No.: 869990-13-6
Synonyms: 1,3-Dipentadecanoyl-2-oleoyl-glycerol
Research Areas:  

Metabolic Disease

15:0-18:1-15:0 TG (1,3-Dipentadecanoyl-2-oleoyl-glycerol) is a triglyceride .
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Cat. No.: HY-W701772
CAS No.: 946524-37-4
Synonyms: 2-OG-d5
2-Oleoylglycerol-d5 (2-OG-d5) is the deuterium labeled 2-Oleoylglycerol (HY-W011121). 2-Oleoylglycerol (2-OG) is a lipid found in the diet. It is a GPR119 agonist, with an EC50 value of 2.5 μM in activating hGPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol enhances the inflammatory response of macrophages and promotes fibrosis by activating the GPR119/TAK1/NF-κB/TGF-β1 signaling pathway. It also stimulates glucagon-like peptide 1 (GLP-1) secretion in vivo. 2-Oleoylglycerol is expected to be used in the research of non-alcoholic steatohepatitis (NASH) [2] .
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Cat. No.: HY-N2512R
CAS No.: 589-68-4
1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans [2] .
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Cat. No.: HY-168385
CAS No.: 66908-04-1
Target:  

Drug Derivative

Research Areas:  

Others

1,3-Dimyristoyl-2-oleoylglycerol is a crystal structure of the beta1 polymorphs of mono-unsaturated triacylglycerols .
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Cat. No.: HY-121476
CAS No.: 183718-70-9
Purity:  ≥98.0%
Target:  

MAGL

Research Areas:  

Neurological Disease

Arachidonoyl Serinol, an endogenous cannabimimetic metabolite, is an inhibitor of monoacylglycerol lipase (MAGL). Arachidonoyl Serinol inhibits the hydrolysis of [ 3H]2-oleoylglycerol and [ 3H]anandamide with IC50s of ~70 μM [2] .
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Cat. No.: HY-131995
CAS No.: 439146-24-4
Target:  

Cannabinoid Receptor

Research Areas:  

Metabolic Disease

O-Arachidonoyl glycidol (compound 1) is a 2-arachidonoylglycerol (2-AG) analog. O-Arachidonoyl glycidol inhibits cytosolic 2-oleoylglycerol (2-OG) hydrolysis with an IC50 value of 4.5 µM. O-Arachidonoyl glycidol blocks 2-OG hydrolysis in membrane fractions and anandamide hydrolysis with IC50s of 19, 12 µM, respectively .
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Cat. No.: HY-W742940
CAS No.: 2519458-54-7
O-Arachidonoyl glycidol-d5 is the deuterium labeled O-Arachidonoyl glycidol (HY-131995). O-Arachidonoyl glycidol (compound 1) is a 2-arachidonoylglycerol (2-AG) analog. O-Arachidonoyl glycidol inhibits cytosolic 2-oleoylglycerol (2-OG) hydrolysis with an IC50 value of 4.5 μM. O-Arachidonoyl glycidol blocks 2-OG hydrolysis in membrane fractions and anandamide hydrolysis with IC50s of 19, 12 μM, respectively .
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Cat. No.: HY-137483
CAS No.: 851761-42-7
Research Areas:  

Endocrinology

Prostaglandin D2 serinol amide is a weak inhibitor of the hydrolysis of [3H]2-oleoylglycerol .
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Cat. No.: HY-118556
CAS No.: 951209-67-9
Research Areas:  

Endocrinology

Prostaglandin E2 serinol amide is a weak inhibitor of the hydrolysis of [3H]2-oleoylglycerol. Prostaglandin E2 serinol amide is non-hydrolyzable to produce PGE2 and thus cannot inhibit leukotriene B4 biosynthesis, superoxide production, migration and antimicrobial peptide release .
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Cat. No.: HY-149507
CAS No.: 109796-58-9
Target:  

Endogenous Metabolite

Research Areas:  

Others

1,3-Capryloyl-2-oleoylglycerol is a triglyceride. 1,3-Capryloyl-2-oleoylglycerol has its hydroxyl groups at the 1 and 3 positions of glycerol acylated by Caprylic acid (HY-41417) and the hydroxyl group at the 2 position acylated by Oleic acid (HY-N1446) in its molecule .
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Cat. No.: HY-W010667
CAS No.: 2190-25-2
Synonyms: 1,3-Dipalmitoyl-2-oleoylglycerol; ?1,3-Palmitin-2-Olein; TG(16:0/18:1/16:0)
(Z)-2-(Oleoyloxy) propane-1,3-diyl dipalmitate (1,3-Dipalmitoyl-2-oleoylglycerol) is an orally active PTP1B inhibitor with an IC50 of 31.01 μM and a Ki of 16.36 μM. (Z)-2-(Oleoyloxy) propane-1,3-diyl dipalmitate also inhibits α-glucosidase with an IC50 of 163.31 μM. It inhibits phosphorylation of p38 MAPK, activates the PI3K/Akt/CREB pathway, and exhibits antioxidant, anti-apoptosis and anti-inflammatory activities, as well as inhibits peroxynitrite-mediated albumin nitration. (Z)-2-(Oleoyloxy) propane-1,3-diyl dipalmitate can be used in studies related to cerebral ischemia-reperfusion injury and diabetes [2] .
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