439146-24-4
439146-24-4
Chemical Structure
O-Arachidonoyl glycidol
- CAS No.: 439146-24-4
- Formula:C23H36O3
- Molecular Weight:360.53
IUPAC Name: oxiran-2-ylmethyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
InChIKey: ACYNJBAUKQMZDF-DOFZRALJSA-N
SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(OCC1CO1)=O
Biological Activity: O-Arachidonoyl glycidol (compound 1) is a 2-arachidonoylglycerol (2-AG) analog. O-Arachidonoyl glycidol inhibits cytosolic 2-oleoylglycerol (2-OG) hydrolysis with an IC50 value of 4.5 µM. O-Arachidonoyl glycidol blocks 2-OG hydrolysis in membrane fractions and anandamide hydrolysis with IC50s of 19, 12 µM, respectively[1].
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O-Arachidonoyl glycidol | O-Arachidonoyl glycidol (compound 1) is a 2-arachidonoylglycerol (2-AG) analog. O-Arachidonoyl glycidol inhibits cytosolic 2-oleoylglycerol (2-OG) hydrolysis with an IC50 value of 4.5 µM. O-Arachidonoyl glycidol blocks 2-OG hydrolysis in membrane fractions and anandamide hydrolysis with IC50s of 19, 12 µM, respectively. | |||||||||||||||||||||
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O-Arachidonoyl glycidol-d5 | O-Arachidonoyl glycidol-d5 is the deuterium labeled O-Arachidonoyl glycidol (HY-131995). O-Arachidonoyl glycidol (compound 1) is a 2-arachidonoylglycerol (2-AG) analog. O-Arachidonoyl glycidol inhibits cytosolic 2-oleoylglycerol (2-OG) hydrolysis with an IC50 value of 4.5 μM. O-Arachidonoyl glycidol blocks 2-OG hydrolysis in membrane fractions and anandamide hydrolysis with IC50s of 19, 12 μM, respectively. | |||||||||||||||||||||
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References
