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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
46 Results for "
ADP-ribosyltransferase
" in MedChemExpress (MCE) Product Catalog:
Products (46)
46 Results for "ADP-ribosyltransferase" in MCE Product Catalog:
7
7 Publications Verification
Cat. No.: HY-P74652
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PARP1; NAD(+) ADP-ribosyltransferase 1; Prev. ADPRT; Poly[ADP-Ribose] Synthase 1; Prev. PPOL; ADPRT 1; ARTD1; PARP-1; Poly-PARP; ADP-ribosyltransferase NAD(+); PARS; NAD(+) ADP-ribosyltransferase; PARP; Poly(ADP-Ribosyl)Transferase; ADP-ribosyltransferase
Species:
Human
Source:
Sf9 insect cells
1
3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells . 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum) .
1
1 Cited Publications
Cat. No.: HY-P80322
Synonyms: SIR2L6, SIRT6, NAD-dependent protein deacylase sirtuin-6, NAD-dependent protein deacetylase sirtuin-6, Protein mono-ADP-ribosyltransferase sirtuin-6, Regulatory protein SIR2 homolog 6, SIR2-like protein 6, hSIRT6
Cat. No.: HY-115501
CAS No.: 1370281-06-3
Target:
Research Areas:
(E)-FOBISIN101 is a 14-3-3 protein-protein interaction (14-3-3 protein-protein interaction) inhibitor, with IC50 values of 9.3 and 16.4 μM for disrupting the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively. (E)-FOBISIN101 inhibits the binding of 14-3-3 to Raf-1 and proline-rich AKT substrate, and neutralizes the ability of 14-3-3 to activate exotoxin S ADP-ribosyltransferase. (E)-FOBISIN101 is applicable to 14-3-3-mediated cancer research .
PARP10-IN-2 is a potent mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 3.64 μM for human PARP10. PARP10-IN-2 reveals potent inhibition on PARP2 and PARP15 with IC50s of 27 μM and 11 μM for human PARP2 and human PARP15, respectively .
PARP10-IN-3 is a selective mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 480 nM for human PARP10. PARP10-IN-3 reveals potent inhibition on PARP2 and PARP15 with IC50s of 1.7 μM for human PARP2 and human PARP15, respectively .
ARTD3/PARP3-IN-1 is an unselective inhibitor of diphtheria toxin-like ADP-ribosyltransferase 3 (ARTD3)/PARP3 .
Cat. No.: HY-148709
CAS No.: 1708103-76-7
Target:
Research Areas:
ARTD10/PARP10-IN-1 (compound 23) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 (ARTD1/PARP1) with IC50s of 1.7 μM, 1.6 μM, 0.8 μM, and 4.4 μM, respectively .
Cat. No.: HY-148710
CAS No.: 1708103-69-8
Target:
Research Areas:
ARTD10/PARP10-IN-2 (compound 19) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 ARTD1/PARP1 with IC50s of 2.0 μM, and 9.7 μM, respectively .
Cat. No.: HY-176456
CAS No.: 3064731-00-3
Target:
Research Areas:
PARP14 inhibitor 2 (Compound 3) is an orally active and highly selective PARP14 inhibitor with an IC50 value of <30 nM. PARP14 inhibitor 2 inhibits the mono-ADP-ribosyltransferase activity of PARP14 and regulates IFN-γ and IL-4 signaling, reversing protumor macrophage polarization and inhibiting anti-tumor inflammatory responses. PARP14 inhibitor 2 is promising for research of PARP14-related diseases such as tumors, atopic dermatitis and autoimmune diseases .
Target:
Research Areas:
TIQ-A is a potent TNKS (poly-ART, PARP) inhibitor, with an IC50 of 24 nM for TNKS2. TIQ-A is a potential anti-ischemic agent .
Cat. No.: HY-121497R
CAS No.: 5813-86-5
Synonyms: 3-MBA (Standard)
Target:
Research Areas:
3-Methoxybenzamide (Standard) is the analytical standard of 3-Methoxybenzamide. This product is intended for research and analytical applications. 3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells . 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum) .
Cat. No.: HY-P73337
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PARP1; NAD(+) ADP-ribosyltransferase 1; Prev. ADPRT; Poly[ADP-Ribose] Synthase 1; Prev. PPOL; ADPRT 1; ARTD1; PARP-1; Poly-PARP; ADP-ribosyltransferase NAD(+); PARS; NAD(+) ADP-ribosyltransferase; PARP; Poly(ADP-Ribosyl)Transferase; ADP-ribosyltransferase
Species:
Mouse
Source:
Sf9 insect cells
Cat. No.: HY-P702866
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PARP3; ADP-ribosyltransferase Diphtheria Toxin-Like 3; Prev. ADPRTL3; NAD(+) ADP-ribosyltransferase 3; PADPRT-3; Poly(ADP-Ribose) Synthetase-3; ADPRT3; NAD+ ADP-ribosyltransferase 3; ARTD3; ADPRT-3; IRT1; ADP-ribosyltransferase (NAD+; Poly (ADP-Ribose) Po
Species:
Human
Source:
E. coli
Cat. No.: HY-P706167
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PARP1; NAD(+) ADP-ribosyltransferase 1; Prev. ADPRT; Poly[ADP-Ribose] Synthase 1; Prev. PPOL; ADPRT 1; ARTD1; PARP-1; Poly-PARP; ADP-ribosyltransferase NAD(+); PARS; NAD(+) ADP-ribosyltransferase; PARP; Poly(ADP-Ribosyl)Transferase; ADP-ribosyltransferase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P76734
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ART1; ADP-ribosyltransferase C2 And C3 Toxin-Like 1; ADP-ribosyltransferase 1; Mono(ADP-Ribosyl)Transferase 1; ARTC1; ADP-ribosyltransferase 2; CD296; CD296 Antigen; ART2; RT6; GPI-Linked NAD(P)(+)--Arginine ADP-ribosyltransferase 1
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P74409
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ART3; Ecto-ADP-ribosyltransferase 3; ADP-ribosyltransferase 3 (Inactive); Mono-ADP-ribosyltransferase; ARTC3; NAD(P)(+)--Arginine ADP-ribosyltransferase; ADP-ribosyltransferase C2 And C3 Toxin-Like 3; Mono(ADP-Ribosyl)Transferase; NAD(P)(+)--Arginine ADP-
Species:
Human
Source:
HEK293
Cat. No.: HY-P87903
Synonyms: ADPRT, PPOL, PARP1, Poly [ADP-ribose] polymerase 1, PARP-1, ADP-ribosyltransferase diphtheria toxin-like 1, DNA ADP-ribosyltransferase PARP1, NAD(+) ADP-ribosyltransferase 1, Poly[ADP-ribose] synthase 1, Protein poly-ADP-ribosyltransferase PARP1, ARTD1, ADPRT 1
Cat. No.: HY-P80265
Synonyms: ADPRT2, ADPRTL2, PARP2, Poly [ADP-ribose] polymerase 2, PARP-2, hPARP-2, ADP-ribosyltransferase diphtheria toxin-like 2, DNA ADP-ribosyltransferase PARP2, NAD(+) ADP-ribosyltransferase 2, Poly[ADP-ribose] synthase 2, Protein poly-ADP-ribosyltransferase PARP2, ARTD2, ADPRT-2, pADPRT-2
Cat. No.: HY-P88031
Synonyms: ADPRT2, ADPRTL2, PARP2, Poly [ADP-ribose] polymerase 2, PARP-2, hPARP-2, ADP-ribosyltransferase diphtheria toxin-like 2, DNA ADP-ribosyltransferase PARP2, NAD(+) ADP-ribosyltransferase 2, Poly[ADP-ribose] synthase 2, Protein poly-ADP-ribosyltransferase PARP2, ARTD2, ADPRT-2, pADPRT-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
