1042780-52-8
1042780-52-8
Chemical Structure
PARP10-IN-2
- CAS No.: 1042780-52-8
- Formula:C14H10N2O2
- Molecular Weight:238.24
IUPAC Name: 4-(4-cyanophenoxy)benzamide
InChIKey: PQQFJYPJKKMNMX-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(C=C1)OC2=CC=C(C(N)=O)C=C2
Biological Activity: PARP10-IN-2 is a potent mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 3.64 μM for human PARP10. PARP10-IN-2 reveals potent inhibition on PARP2 and PARP15 with IC50s of 27 μM and 11 μM for human PARP2 and human PARP15, respectively[1].
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PARP10-IN-2 | 98.07% | PARP10-IN-2 is a potent mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 3.64 μM for human PARP10. PARP10-IN-2 reveals potent inhibition on PARP2 and PARP15 with IC50s of 27 μM and 11 μM for human PARP2 and human PARP15, respectively. | ||||||||||||||||||||
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References
Keywords
