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AMP (Standard)

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25

Inhibitors & Agonists

12

Natural
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-A0181R
    Adenosine monophosphate (Standard)

    AMP (Standard)

    		 Reference Standards Endogenous Metabolite Adenosine Receptor HSV Infection Metabolic Disease
    Adenosine monophosphate (Standard) is the analytical standard of Adenosine monophosphate (HY-A0181). This product is intended for research and analytical applications. Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .
    Adenosine monophosphate (Standard)
  • HY-B0272R
    Rifampicin (Standard)

    RifAMPin (Standard); Rifamycin AMP (Standard)

    		 Reference Standards Bacterial Influenza Virus Antibiotic Orthopoxvirus Infection Cancer
    Rifampicin (Standard) is the analytical standard of Rifampicin. This product is intended for research and analytical applications. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. Rifampicin shows anti-orthopoxvirus activity.
    Rifampicin (Standard)
  • HY-B1511R
    Cyclic AMP (Standard)

    Cyclic adenosine monophosphate (Standard); Adenosine cyclic 3', 5'-monophosphate (Standard); cAMP (Standard)

    		 Endogenous Metabolite Reference Standards Cancer
    Cyclic AMP (Standard) is the analytical standard of Cyclic AMP. Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .
    Cyclic AMP (Standard)
  • HY-W040329R
    2'-Deoxyadenosine (Standard)

    		Reference Standards Endogenous Metabolite Nucleoside Antimetabolite/Analog Caspase Apoptosis Metabolic Disease Endocrinology Cancer
    2'-Deoxyadenosine (Standard) is the analytical standard of 2'-Deoxyadenosine (HY-W040329). This product is intended for research and analytical applications. 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer .
    2'-Deoxyadenosine (Standard)
  • HY-113469R
    Cyclic GMP (Standard)

    		Endogenous Metabolite Reference Standards Infection Cardiovascular Disease Inflammation/Immunology
    Cyclic GMP (Standard) is the analytical standard of Cyclic GMP (HY-113469). This product is intended for research and analytical applications. Cyclic GMP (cGMP), an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses .
    Cyclic GMP (Standard)
  • HY-W016009R
    2'-Deoxyadenosine-5'-monophosphate (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease
    2'-Deoxyadenosine-5'-monophosphate (Standard) is the analytical standard of 2'-Deoxyadenosine-5'-monophosphate. This product is intended for research and analytical applications. 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
    2'-Deoxyadenosine-5'-monophosphate (Standard)
  • HY-A0181AR
    Adenosine 5'-monophosphate monohydrate (Standard)

    5'-AMP monohydrate (Standard)

    		 Reference Standards Endogenous Metabolite Adenosine Receptor HSV Infection Metabolic Disease
    Cyanidin 3-sambubioside (chloride) (Standard) is the analytical standard of Cyanidin 3-sambubioside (chloride). This product is intended for research and analytical applications. Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride), a major anthocyanin, a natural colorant, and is a potent NO inhibitor. Cyanidin 3-sambubioside chloride is a H274Y mutation inhibitor, and inhibits influenza neuraminidase activity with an IC50 of 72 μM. Cyanidin 3-sambubioside chloride inhibits angiotensin-converting enzyme (ACE) activity and has antioxidant, anti-angiogenic and antiviral properties .
    Adenosine 5'-monophosphate monohydrate (Standard)
  • HY-B0277AR
    Vidarabine phosphate (Standard)

    ara-AMP (Standard); ara-A 5'-monophosphate (Standard)

    		 Reference Standards Apoptosis Drug Intermediate Fungal Reactive Oxygen Species (ROS) EBV HSV DNA/RNA Synthesis Infection
    Vidarabine phosphate (ara-AMP; ara-A 5'-monophosphate) (Standard) is the analytical standard of Vidarabine phosphate. This product is intended for research and analytical applications. Vidarabine phosphate is a purine nucleoside antiviral agent and a prodrug of Vidarabine (HY-B0277). Vidarabine phosphate is rapidly converted into the antiviral active Vidarabine in vivo, which selectively inhibits viral DNA polymerase and cellular ribonucleotide reductase, thereby blocking viral replication. Vidarabine phosphate also exhibits antifungal activity, induces late-stage cellular apoptosis, and causes cell cycle arrest. Vidarabine phosphate can be used in research related to severe chronic active Epstein-Barr virus (EBV) infection, herpes infection, and candidiasis.
    Vidarabine phosphate (Standard)
  • HY-124151R
    Adenosine-2'-monophosphate (Standard)

    2'-AMP (Standard); Adenosine 2'-phosphate (Standard); AMP 2'-phosphate (Standard)

    		 Reference Standards Adenosine Receptor Endogenous Metabolite Neurological Disease
    Bisphenol A diglycidyl ether (Standard) is the analytical standard of Bisphenol A diglycidyl ether. This product is intended for research and analytical applications. Bisphenol A diglycidyl ether is used as a stabilizer and embedding agent.
    Adenosine-2'-monophosphate (Standard)
  • HY-W011293R
    DTA (Standard)

    2,4-Disulfamyl-5-trifluoromethylaniline (Standard)

    		 Reference Standards Phosphodiesterase (PDE) Others
    DTA (Standard) is the analytical standard of DTA. This product is intended for research and analytical applications. DTA (2,4-Disulfamyl-5-trifluoromethylaniline) is a cyclic AMP phosphodiesterase inhibitor that binds to erythrocyte carbonic anhydrase .
    DTA (Standard)
  • HY-B1056R
    Procodazole (Standard)

    Propazol (Standard); 2-Benzimidazolepropionic acid (Standard)

    		 Reference Standards Bacterial Parasite Antibiotic Carbonic Anhydrase Infection Cancer
    DTA (Standard) is the analytical standard of DTA. This product is intended for research and analytical applications. DTA (2,4-Disulfamyl-5-trifluoromethylaniline) is a cyclic AMP phosphodiesterase inhibitor that binds to erythrocyte carbonic anhydrase .
    Procodazole (Standard)
  • HY-100126R
    Tubercidin (Standard)

    7-Deazaadenosine (Standard)

    		 Reference Standards Bacterial DNA/RNA Synthesis Influenza Virus Antibiotic Infection
    Tubercidin (Standard) is the analytical standard of Tubercidin. This product is intended for research and analytical applications. Tubercidin (7-Deazaadenosine) is an antibiotic obtained from Streptomyces tubercidicus. Tubercidin inhibits the growth of Streptococcus faecalis (8043) with an IC50 of 0.02 μM[1]. Tubercidin inhibits polymerases by incorporating DNA or RNA, thereby inhibiting DNA replication, RNA and protein synthesis[2]. Tubercidin is a weak inhibitor of adenosine phosphorylase, and interferes with the phosphorylation of adenosine and AMP[1]. Tubercidin has antiviral activity[2].
    Tubercidin (Standard)
  • HY-B1730R
    Phensuximide (Standard)

    		Cyclic GMP-AMP Synthase Reference Standards Neurological Disease Metabolic Disease
    Phensuximide (Standard) is the analytical standard of Phensuximide. This product is intended for research and analytical applications. Phensuximide is an orally active succinimide antiepileptic and anticonvulsant agent. Phensuximide inhibits cyclic AMP and cyclic GMP accumulation in depolarized brain tissue. Phensuximide can be used for the study of seizure and petit mal .
    Phensuximide (Standard)
  • HY-N6258R
    Kahweol (Standard)

    		Reference Standards AMPK Apoptosis Metabolic Disease
    Kahweol (Standard) is the analytical standard of Kahweol. This product is intended for research and analytical applications. Kahweol is one of the consituents of the coffee from Coffea Arabica with anti-inflammatory anti-angiogenic, and anti-cancerous activities. Kahweol inhibits adipogenesis and increase glucose uptake by AMP-activated protein kinase (AMPK) activation. Kahweol induces apoptosis.
    Kahweol (Standard)
  • HY-N0579R
    Fraxin (Standard)

    Fraxoside (Standard)

    		 Reference Standards Phosphodiesterase (PDE) Inflammation/Immunology
    Fraxin (Standard) is the analytical standard of Fraxin. This product is intended for research and analytical applications. Fraxin isolated from Cortex Fraxini, is a glucoside of fraxetin and reported to exert potent anti-oxidative stress action , anti-inflammatory and antimetastatic properties. Fraxin shows its antioxidative effect through inhibition of cyclo AMP phosphodiesterase enzyme .
    Fraxin (Standard)
  • HY-123085R
    Alloxazine (Standard)

    Isoalloxazine (Standard)

    		 Adenosine Receptor Reference Standards Cancer
    Alloxazine (Standard) is the analytical standard of Alloxazine. This product is intended for research and analytical applications. Alloxazine is a selective A2b antagonist. Alloxazine completely block 5’N-Ethylcarboxamido adenosine (NECA)-mediated cyclic AMP accumulation with an IC50 of 2.9 μM. Alloxazine can be used for the research of cancer .
    Alloxazine (Standard)
  • HY-113469AR
    Cyclic GMP sodium (Standard)

    		Reference Standards Endogenous Metabolite Infection Cardiovascular Disease Inflammation/Immunology
    Cyclic GMP sodium (Standard) is the analytical standard of Cyclic GMP sodium (HY-113469A). This product is intended for research and analytical applications. Cyclic GMP (cGMP) sodium, an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP sodium occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses .
    Cyclic GMP sodium (Standard)
  • HY-B0763R
    Ibudilast (Standard)

    KC-404 (Standard); AV-411 (Standard); MN-166 (Standard)

    		 Reference Standards Phosphodiesterase (PDE) Inflammation/Immunology Cancer
    Ibudilast (Standard) is the analytical standard of Ibudilast. This product is intended for research and analytical applications. Ibudilast (KC-404; AV-411; MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia .
    Ibudilast (Standard)
  • HY-16397R
    Phenformin (Standard)

    Phenethylbiguanide (Standard)

    		 Reference Standards Apoptosis mTOR Autophagy Mitochondrial Metabolism AMPK Neurological Disease Metabolic Disease Cancer
    Phenformin (Phenethylbiguanide) (Standard) is the analytical standard of Phenformin (HY-16397). This product is intended for research and analytical applications. Phenformin (Phenethylbiguanide) is an orally active biguanide hypoglycemic agent. Phenformin inhibits mitochondrial respiratory chain complex I, leading to an increased AMP/ATP ratio, activation of AMPK, and subsequent inhibition of the mTOR pathway, thereby suppressing cell proliferation, inducing apoptosis and autophagy. Phenformin inhibits cancer stem cells (CSCs) and possesses potent antitumor potential.
    Phenformin (Standard)
  • HY-16397AR
    Phenformin hydrochloride (Standard)

    Phenethylbiguanide hydrochloride (Standard)

    		 Reference Standards Apoptosis mTOR Autophagy Mitochondrial Metabolism AMPK Neurological Disease Metabolic Disease Cancer
    Phenformin (Phenethylbiguanide) hydrochloride (Standard) is the analytical standard of Phenformin hydrochloride (HY-16397). This product is intended for research and analytical applications. Phenformin hydrochloride (Phenethylbiguanide) is an orally active biguanide hypoglycemic agent. Phenformin hydrochloride inhibits mitochondrial respiratory chain complex I, leading to an increased AMP/ATP ratio, activation of AMPK, and subsequent inhibition of the mTOR pathway, thereby suppressing cell proliferation, inducing apoptosis and autophagy. Phenformin hydrochloride inhibits cancer stem cells (CSCs) and possesses potent antitumor potential.
    Phenformin hydrochloride (Standard)
  • HY-W011683R
    2'-Deoxyadenosine monohydrate (Standard)

    		Reference Standards Endogenous Metabolite Nucleoside Antimetabolite/Analog Caspase Apoptosis Metabolic Disease Endocrinology Cancer
    2'-Deoxyadenosine monohydrate (Standard) is the analytical standard of 2'-Deoxyadenosine monohydrate ((HY-W011683). This product is intended for research and analytical applications. 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer .
    2'-Deoxyadenosine monohydrate (Standard)
  • HY-131763R
    2'-O-MB-cAMP sodium (Standard)

    2'-O-Monobutyryl cyclic AMP sodium (Standard)

    		 Drug Intermediate Reference Standards Others
    2'-O-MB-cAMP (sodium) (Standard) is the analytical standard of 2'-O-MB-cAMP (sodium). This product is intended for research and analytical applications.
    2'-O-MB-cAMP sodium (Standard)
  • HY-107988R
    MK-3903 (Standard)

    		Reference Standards AMPK Metabolic Disease
    MK-3903 (Standard) is the analytical standard of MK-3903 (HY-107988). This product is intended for research and analytical applications. MK-3903 is a potent and selective AMP-activated protein Kinase (AMPK) activator with an EC50 of 8 nM.
    MK-3903 (Standard)
  • HY-N0165R
    Methyl-Hesperidin (Standard)

    		Reference Standards HIV Reverse Transcriptase Cardiovascular Disease Infection Inflammation/Immunology
    Methyl-Hesperidin (Standard) is the analytical standard of Methyl-Hesperidin (HY-N0165). This product is intended for research and analytical applications. Methyl-Hesperidin is a glycoside compound. Methyl-Hesperidin has hypotensive, coronary dilating, smooth muscle relaxing, capillary stabilizing, choleretic, and anti-ulcer activities. Methyl-Hesperidin act as a competitive substrate to inhibit HIV-1 reverse transcriptase activity. Methyl-Hesperidin potentiates coronary dilating actions of adenine nucleotides and 3'-AMP, enhances depressant action on isolated atria, and prolongs adenosine- and ATP-induced heart block in guinea pigs .
    Methyl-Hesperidin (Standard)
  • HY-10081R
    GS-6201 (Standard)

    CVT-6883 (Standard)

    		 Adenosine Receptor Reference Standards Inflammation/Immunology
    GS-6201 (Standard) is the analytical standard of GS-6201 (HY-10081). This product is intended for research and analytical applications. GS-6201 (CVT-6883) is a selective adenosine A2B receptor antagonist. GS-6201 displays high affinity and selectivity for the human adenosine A2B receptors (Ki=22 nM) . GS-6201 reduces caspase-1 activity in the heart, and attenuates cardiac remodeling after acute myocardial infarction (AMI) in the mouse . GS-62013 attenuates the airway reactivity induced by NECA, AMP, or allergen in sensitized mice .
    GS-6201 (Standard)

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