2 Results for "

AY77

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "AY77" in MCE Product Catalog:

Cat. No.: HY-138951
CAS No.: 1835734-92-3
AY77 is a calcium-biased PAR2 agonist. AY77 shows an EC50 of 0.17 and 2 nM in PAR2-mediated the activation in the Gq pathway and recruitment of β-arrestin-2, respectively. AY77 potently induces intracellular Ca 2+ release .
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Cat. No.: HY-P3259
CAS No.: 2093408-03-6
AY254 is an analogue of AY77 (HY-138951). AY254 is ERK-biased PAR2 agonist with an EC50 of 2 nM. AY254 relieves cytokine-induced caspase 3/8 activation. AY254 also promotes scratch-wound healing and induced IL-8 secretion via PAR2-ERK1/2 signaling
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