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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
206 Results for "
B cell antigen receptor
" in MedChemExpress (MCE) Product Catalog:
Products (206)
206 Results for "B cell antigen receptor" in MCE Product Catalog:
5
5 Cited Publications
Synonyms: P505-15; PRT-2607; BIIB-057
Research Areas:
PRT062607 (P505-15; PRT-2607) is an orally active ATP-competitive Syk inhibitor with an IC50 value of 1 nM, and exhibits at least 80-fold selectivity over other kinases. PRT062607 blocks B cell antigen receptor-mediated activation, Fcε receptor 1-mediated basophil degranulation and microglial phagocytosis, and induces caspase-dependent apoptosis and microglial death. PRT062607 inhibits tumor growth and peripheral nerve injury-induced mechanical allodynia, and prevents neuronal loss. PRT062607 can be used in research related to rheumatoid arthritis, chronic lymphocytic leukemia, non-Hodgkin's lymphoma, neurodegenerative diseases and neuropathic pain .
3
Orelabrutinib (ICP-022) is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor with potential antineoplastic activity. Orelabrutinib prevents both the activation of the B-cell antigen receptor (BCR) signaling pathway and BTK-mediated activation of downstream survival pathways, inhibiting the growth of malignant B-cells that overexpress BTK .
3
2
2 Cited Publications
Cat. No.: HY-P73094
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ERBB2; P185erbB2; Prev. NGL; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog); HER2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2 Isoform C; receptor Tyrosine-Protein Kinase ErbB-2; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; Proto-Oncogene C-ErbB-2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Proto-Oncogene Neu; receptor Tyrosine-Protein Kinase ErbB-2 Variant; P185(ErbB2); Truncated HER2 Splice Variant P100; C-ERB-2; receptor Protein-Tyrosine Kinase; C-ERB2; Metastatic Lymph Node Gene 19; MLN-19; Alternative Protein ERBB2; HER-2; C-Erb B2/Neu Protein; CD340; CD340 antigen; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; HER-2/Neu; Tyrosine Kinase-Type cell Surface receptor HER2; Herstatin; Neuro/Glioblastoma Derived Oncogene Homolog; VSCN2; Human Epidermal Growth Factor receptor 2; MLN19; Metastatic Lymph Node Gene 19 Protein; TKR1; Erb-B2 receptor Tyrosine Kinase 2; MLN 19
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P78070
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor receptor Superfamily, Member 17; BCM; B cell Maturation antigen; Tumor Necrosis Factor receptor Superfamily Member 17; B-cell Maturation Factor; B-cell Maturation Protein; CD269 antigen; TNF receptor
Species:
Human
Source:
HEK293
1
1
1 Cited Publications
Cat. No.: HY-P80116
Synonyms: Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody;
cell growth inhibiting protein 40 antibody;
cell proliferation inducing protein 61 antibody;
EGF R antibody;
EGFR antibody;
EGFR_HUMAN antibody;
Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) antibody;
Epidermal growth factor receptor antibody;
erb-b2 receptor tyrosine kinase 1 antibody;
ERBB antibody;
ERBB1 antibody;
Errp antibody;
HER1 antibody;
mENA antibody;
NISBD2 antibody;
Oncogen ERBB antibody;
PIG61 antibody;
Proto-oncogene c-ErbB-1 antibody;
receptor tyrosine protein kinase ErbB 1 antibody;
receptor tyrosine-protein kinase ErbB-1 antibody;
SA7 antibody;
Species antigen 7 antibody;
Urogastrone antibody;
v-erb-b Avian erythroblastic leukemia viral oncogen homolog antibody;
wa2 antibody;
Wa5 antibody
Cat. No.: HY-153085
Target:
Research Areas:
CD19 CAR circRNA will express CD19 car protein, and can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction.
Cat. No.: HY-147584
CAS No.: 2764674-60-2
Target:
Research Areas:
BTK-IN-14 is a potent inhibitor of BTK. BTK plays an important role in signaling mediated by B cell antigen receptor (BCR) and Fcγreceptor (FcγR) in B cells and myeloid cells, respectively. BTK-IN-14 has the potential for the research of related diseases, especially autoimmune diseases, inflammatory diseases or cancer (extracted from patent WO2022057894A1, compound 1) .
Cat. No.: HY-174738
Target:
Research Areas:
Human CD40 mRNA encodes the human CD40 molecule (CD40) protein, a member of the TNF-receptor superfamily. CD40 is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
Cat. No.: HY-157288
Target:
Research Areas:
(R)-Phe-A110/B319, a hapten, is a selective binder to tumor-associated antigens. (R)-Phe-A110/B319 has a 20-fold higher affinity towards the H1047R mutant of p110α in the p110α/p85α PI3K complex. (R)-Phe-A110/B319 can be used for the research of conditional chimeric antigen receptor T (CAR-T) cell activation and tumor targeting .
Cat. No.: HY-147581
CAS No.: 2765852-46-6
Target:
Research Areas:
BTK-IN-11 is a potent inhibitor of BTK. BTK plays an important role in signaling mediated by B cell antigen receptor (BCR) and Fcγreceptor (FcγR) in B cells and myeloid cells, respectively. BTK-IN-11 has the potential for the research of related diseases, especially autoimmune diseases, inflammatory diseases or cancer (extracted from patent WO2022063101A1, compound Z2) .
Cat. No.: HY-P70541
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD79B; CD79b Molecule, Immunoglobulin-Associated Beta; Prev. IGB; B-cell-Specific Glycoprotein B29; Ig-Beta; B-cell antigen receptor Complex-Associated Protein Beta Chain Isoform 3; B29; CD79b antigen; B-cell antigen receptor Complex-Associated Protein Be
Species:
Human
Source:
HEK293
Cat. No.: HY-P72707
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD79B; CD79b Molecule, Immunoglobulin-Associated Beta; Prev. IGB; B-cell-Specific Glycoprotein B29; Ig-Beta; B-cell antigen receptor Complex-Associated Protein Beta Chain Isoform 3; B29; CD79b antigen; B-cell antigen receptor Complex-Associated Protein Be
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P75659
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD79B; CD79b Molecule, Immunoglobulin-Associated Beta; Prev. IGB; B-cell-Specific Glycoprotein B29; Ig-Beta; B-cell antigen receptor Complex-Associated Protein Beta Chain Isoform 3; B29; CD79b antigen; B-cell antigen receptor Complex-Associated Protein Be
Species:
Rat
Source:
HEK293
Cat. No.: HY-P75658
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD79B; CD79b Molecule, Immunoglobulin-Associated Beta; Prev. IGB; B-cell-Specific Glycoprotein B29; Ig-Beta; B-cell antigen receptor Complex-Associated Protein Beta Chain Isoform 3; B29; CD79b antigen; B-cell antigen receptor Complex-Associated Protein Be
Species:
Rat
Source:
HEK293
Cat. No.: HY-P78263
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD79B; CD79b Molecule, Immunoglobulin-Associated Beta; Prev. IGB; B-cell-Specific Glycoprotein B29; Ig-Beta; B-cell antigen receptor Complex-Associated Protein Beta Chain Isoform 3; B29; CD79b antigen; B-cell antigen receptor Complex-Associated Protein Be
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P704492
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD79B; CD79b Molecule, Immunoglobulin-Associated Beta; Prev. IGB; B-cell-Specific Glycoprotein B29; Ig-Beta; B-cell antigen receptor Complex-Associated Protein Beta Chain Isoform 3; B29; CD79b antigen; B-cell antigen receptor Complex-Associated Protein Be
Species:
Human
Source:
HEK293
Cat. No.: HY-P70768
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD79B; CD79b Molecule, Immunoglobulin-Associated Beta; Prev. IGB; B-cell-Specific Glycoprotein B29; Ig-Beta; B-cell antigen receptor Complex-Associated Protein Beta Chain Isoform 3; B29; CD79b antigen; B-cell antigen receptor Complex-Associated Protein Be
Species:
Human
Source:
HEK293
Cat. No.: HY-P72708
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD79B; CD79b Molecule, Immunoglobulin-Associated Beta; Prev. IGB; B-cell-Specific Glycoprotein B29; Ig-Beta; B-cell antigen receptor Complex-Associated Protein Beta Chain Isoform 3; B29; CD79b antigen; B-cell antigen receptor Complex-Associated Protein Be
Species:
Rhesus Macaque
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
