2764674-60-2
Chemical Structure
BTK-IN-14
- CAS No.: 2764674-60-2
- Formula:C38H44N8O4
- Molecular Weight:676.81
IUPAC Name: 2-(5-((5-((2S,6S)-2,6-dimethyl-4-(oxetan-3-yl)piperazin-1-yl)pyridin-2-yl)amino)-3'-(hydroxymethyl)-1-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridin]-2'-yl)-7,7-dimethyl-7,8-dihydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one
InChIKey: MKOCXBGRGYGWAO-ZEQRLZLVSA-N
SMILES: C[C@H]1CN(C[C@@H](N1C2=CC=C(N=C2)NC3=CC(C4=CC=NC(N5C=CN6C(C5=O)=CC7=C6CC(C)(C7)C)=C4CO)=CN(C3=O)C)C)C8COC8
Biological Activity: BTK-IN-14 is a potent inhibitor of BTK. BTK plays an important role in signaling mediated by B cell antigen receptor (BCR) and Fcγreceptor (FcγR) in B cells and myeloid cells, respectively. BTK-IN-14 has the potential for the research of related diseases, especially autoimmune diseases, inflammatory diseases or cancer (extracted from patent WO2022057894A1, compound 1)[1].
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BTK-IN-14 | BTK-IN-14 is a potent inhibitor of BTK. BTK plays an important role in signaling mediated by B cell antigen receptor (BCR) and Fcγreceptor (FcγR) in B cells and myeloid cells, respectively. BTK-IN-14 has the potential for the research of related diseases, especially autoimmune diseases, inflammatory diseases or cancer (extracted from patent WO2022057894A1, compound 1). | |||||||||||||||||||||
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Keywords