7 Results for "

BJAB cell

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "BJAB cell" in MCE Product Catalog:

1
1 Cited Publications
Referencia número: HY-107769
No. CAS: 157922-77-5
Pureza:  99.82%
Synonyms: CBI-TMI
Áreas de investigación:  

Cancer

Duocarmycin TM (CBI-TMI) is a potent antitumor antibiotic. Duocarmycin TM induces a sequence-selective alkylation of duplex DNA.
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Referencia número: HY-112099
No. CAS: 1639351-92-0
Pureza:  ≥95.0%
Target:  

ADC Linkers

Áreas de investigación:  

Cancer

Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).
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Referencia número: HY-N3055
No. CAS: 31685-80-0
Pinusolide is an AMPK activator and PAF receptor antagonist. Pinusolide activates AMPK, phosphorylates ACC, enhances IRS-1 tyrosine phosphorylation, boosts glucose uptake, and modulates insulin signaling. Pinusolide inhibits caspase-3/7 activation, intracellular calcium elevation, reactive oxygen species overproduction, lipid peroxidation, and tumor cell proliferation. Pinusolide stabilizes superoxide dismutase activity, reduces apoptotic hallmarks, induces mitochondrial pathway apoptosis, and triggers DNA fragmentation. Pinusolide can be used for the research of type 2 diabetes, neurodegenerative diseases, acute lymphoblastic leukemia, acute myeloid leukemia, and Burkitt lymphoma .
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Referencia número: HY-107769R
No. CAS: 157922-77-5
Synonyms: CBI-TMI (Standard)
Áreas de investigación:  

Cancer

Duocarmycin TM (Standard) is the analytical standard of Duocarmycin TM (HY-107769). This product is intended for research and analytical applications. Duocarmycin TM (CBI-TMI) is a potent antitumor antibiotic. Duocarmycin TM induces a sequence-selective alkylation of duplex DNA.
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Referencia número: HY-184482
No. CAS: 1019642-47-7
Synonyms: BPC-Sia-LacNAc-N3
Target:  

Drug Intermediate

Áreas de investigación:  

Cancer

CD22L-N3 (BPC-Sia-LacNAc-N3) is a pharmaceutical intermediate that can be used to synthesize CD22-specific trisaccharide ligands. CD22L-N3 is applicable to the research of B-cell lymphoma .
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Referencia número: HY-185492
No. CAS: 1799659-90-7
Áreas de investigación:  

Cancer

MC-cBu-Cit-seco-CBI dimer (Compound 10) is a conjugate of an ADC drug toxin molecule and a linker, which consists of a DNA alkylating agent connected to a reactive maleimide via a protease-cleavable peptidomimetic linker .
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Referencia número: HY-P11779
No. CAS: 2768774-89-4
Áreas de investigación:  

Cancer

Ac-RKAA-PABC-MMAE is a Drug-Linker Conjugates for ADC. Ac-RKAA-PABC-MMAE consists of the ADC Cytotoxin MMAE (HY-15162) and a linker. Ac-RKAA-PABC-MMAE can be used for synthesis of ADCs .
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