7 Results for "

BJAB cell

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "BJAB cell" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-107769
CAS No.: 157922-77-5
Purity:  99.82%
Synonyms: CBI-TMI
Research Areas:  

Cancer

Duocarmycin TM (CBI-TMI) is a potent antitumor antibiotic. Duocarmycin TM induces a sequence-selective alkylation of duplex DNA.
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Cat. No.: HY-112099
CAS No.: 1639351-92-0
Purity:  ≥95.0%
Target:  

ADC Linkers

Research Areas:  

Cancer

Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).
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Cat. No.: HY-N3055
CAS No.: 31685-80-0
Pinusolide is an AMPK activator and PAF receptor antagonist. Pinusolide activates AMPK, phosphorylates ACC, enhances IRS-1 tyrosine phosphorylation, boosts glucose uptake, and modulates insulin signaling. Pinusolide inhibits caspase-3/7 activation, intracellular calcium elevation, reactive oxygen species overproduction, lipid peroxidation, and tumor cell proliferation. Pinusolide stabilizes superoxide dismutase activity, reduces apoptotic hallmarks, induces mitochondrial pathway apoptosis, and triggers DNA fragmentation. Pinusolide can be used for the research of type 2 diabetes, neurodegenerative diseases, acute lymphoblastic leukemia, acute myeloid leukemia, and Burkitt lymphoma .
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Cat. No.: HY-107769R
CAS No.: 157922-77-5
Synonyms: CBI-TMI (Standard)
Duocarmycin TM (Standard) is the analytical standard of Duocarmycin TM (HY-107769). This product is intended for research and analytical applications. Duocarmycin TM (CBI-TMI) is a potent antitumor antibiotic. Duocarmycin TM induces a sequence-selective alkylation of duplex DNA.
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Cat. No.: HY-184482
CAS No.: 1019642-47-7
Synonyms: BPC-Sia-LacNAc-N3
Target:  

Drug Intermediate

Research Areas:  

Cancer

CD22L-N3 (BPC-Sia-LacNAc-N3) is a pharmaceutical intermediate that can be used to synthesize CD22-specific trisaccharide ligands. CD22L-N3 is applicable to the research of B-cell lymphoma .
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Cat. No.: HY-185492
CAS No.: 1799659-90-7
MC-cBu-Cit-seco-CBI dimer (Compound 10) is a conjugate of an ADC drug toxin molecule and a linker, which consists of a DNA alkylating agent connected to a reactive maleimide via a protease-cleavable peptidomimetic linker .
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Cat. No.: HY-P11779
CAS No.: 2768774-89-4
Ac-RKAA-PABC-MMAE is a Drug-Linker Conjugates for ADC. Ac-RKAA-PABC-MMAE consists of the ADC Cytotoxin MMAE (HY-15162) and a linker. Ac-RKAA-PABC-MMAE can be used for synthesis of ADCs .
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