1 Result for "

C166 vascular endothelial cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "C166 vascular endothelial cells" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-B1076
CAS No.: 2668-66-8
Synonyms: HMS; 6α-Methyl-11β-hydroxyprogesterone
Target:  

VEGFR CCR STAT

Research Areas:  

Neurological Disease

Medrysone (HMS; 6α-Methyl-11β-hydroxyprogesterone) is a STAT6 modulator and M2 macrophage polarization inducer. Medrysone enhances IL-4-triggered STAT6 activation, upregulates the expression of M2 markers, and promotes the secretion of VEGF and CCL2. Medrysone also enhances the pro-migratory activity of M2-like macrophages toward endothelial cells. By regulating macrophage polarization and related repair pathways, Medrysone significantly promotes corneal wound repair in a rat mechanical injury model. Medrysone can be used for research related to corneal injury .
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