4 Results for "

CC Chemokine Receptor 7

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "CC Chemokine Receptor 7" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-133073
CAS No.: 681514-83-0
Purity:  99.19%
Synonyms: CCR7-Cmp2105
Research Areas:  

Cancer

CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM .
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1
1 Cited Publications
Cat. No.: HY-P81143
Synonyms: CCR7_HUMAN; BLR 2; BLR2; C C Chemokine Receptor type 7; C C CKR 7; CC Chemokine Receptor 7; CC Chemokine Receptor type 7; CC CKR 7; CCCKR7; CCR 7; CD 197; CD197; CD197 antigen; CDW197; Chemokine C C motif Receptor 7; Chemokine C C Receptor 7; Chemokine Receptor 7-like protein; EBI 1; EBI1; Ebi1h; EBV Induced G Protein Coupled Receptor 1; Epstein Barr virus induced G protein coupled Receptor; Epstein Barr virus induced gene 1; EVI 1; EVI1; Lymphocyte Specific G Protein Coupled Peptide Receptor; MGC108519; MIP 3 beta Receptor; MIP3 Beta Receptor.

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-174742
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human CCR7 mRNA encodes the human C-C motif chemokine receptor 7 (CCR7) protein, a member of the G protein-coupled receptor family. CCR7 has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation.
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Cat. No.: HY-P11928
CAS No.: 3121532-43-9
Target:  

CCR ERK

Research Areas:  

Cancer

TC6-D3 is a proteolysis-resistant peptide and also a CC chemokine receptor 7 (CCR7) inhibitor, with a Kd value of 403 nM against mouse targets. TC6-D3 blocks the interaction between CCR7 and its ligands CCL19 and CCL21, and inhibits the activation of the ERK1/2 pathway. TC6-D3 reduces the migratory capacity of tumor cells in vitro. TC6-D3 inhibits tumor growth and lymph node metastasis in vivo. TC6-D3 restores T cell cytotoxicity, promotes CD8+ T cell infiltration, and enhances anti-tumor immune responses. TC6-D3 can be used in studies related to lymph node metastasis .
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