4 Results for "

CDR1

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "CDR1" in MCE Product Catalog:

Cat. No.: HY-P3560
CAS No.: 433922-67-9
Synonyms: TV 4710
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology

Edratide (TV 4710) is a synthetic peptide of 19 amino acid based on the complementarity-determining region 1 (CDR1) of a human anti-DNA antibody that expresses a major idiotype denoted 16/6 Id. Edratide reduces the rates of apoptosis (Apoptosis) and down-regulates of caspase-8 and caspase-3, up-regulates Bcl-xL. Edratide has the potential for the research of systemic lupus erythematosus (SLE) [1] .
Cat. No.: HY-144694
CAS No.: 2700035-54-5
Target:  

HSP HDAC Fungal

Research Areas:  

Infection

HDAC/HSP90-IN-3 (compound J5) is a potent and selective fungal Hsp90 and HDAC dual inhibitor, with IC50 values of 0.83 and 0.91 μM, respectively. HDAC/HSP90-IN-3 shows antifungal activity against azole resistant C. albicans. HDAC/HSP90-IN-3 can suppress important virulence factors and down-regulate drug-resistant genes ERG11 and CDR1 [1].
Cat. No.: HY-145814
CAS No.: 2765247-36-5
Target:  

HSP Fungal

Research Areas:  

Infection

HSP90-IN-9 is a potent and selective HSP90 inhibitor. HSP90-IN-9 displays a fungicidal effect in a dose-dependent manner. HSP90-IN-9 inhibits fungal biofilm formation and fungal morphological changes after being combined with FLC. HSP90-IN-9 recovers FLC resistance by down-regulating the expression of related genes (ERG11, CDR1 and CDR2) [1].
Cat. No.: HY-N19799
CAS No.: 1464778-45-7
Target:  

Fungal

Diorcinol D is a natural product with antifungal activity. Diorcinol D inhibits CYP51 expression, reduces Cdr1 expression, blocks efflux pump activity, and impedes ergosterol biosynthesis. It inhibits planktonic and biofilm growth of Candida albicans. Diorcinol D is applicable to research related to fungal infections [1].