37 Results for "

CUT

" in MedChemExpress (MCE) Product Catalog:
Products (37)

37 Results for "CUT" in MCE Product Catalog:

13
13 Publications Verification
Cat. No.: HY-110353
CAS No.: 1821387-73-8
Purity:  99.96%
Research Areas:  

Inflammation/Immunology Cancer

CU-T12-9 is a specific TLR1/2 agonist with EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay. CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and iNOS .
7
7 Cited Publications
Cat. No.: HY-W019711
CAS No.: 14371-10-9
trans-Cinnamaldehyde can be used to prepare highly polyfunctionalized furan ring by reaction of alkyl isocyanides with dialkyl acetylenedicarboxylate . trans-Cinnamaldehyde can be used to synthesize trans-cinnamaldehyde -β-cyclodextrin complex, an antimicrobial edible coating that increases the shelf life of fresh-cut fruits .
7
7 Cited Publications
Cat. No.: HY-P2902
CAS No.: 9001-37-0
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation .
1
1 Cited Publications
Cat. No.: HY-W250307
CAS No.: 2217-79-0
Diphenyliodonium iodide is an inhibitor of reactive oxygen species (ROS). Diphenyliodonium iodide can inhibit the accumulation of bisdemethoxycurcumin in fresh-cut yam by inhibiting the phenylpropanoid pathway and the biosynthesis of bisdemethoxycurcumin, thereby preventing the yellowing of fresh-cut yam. Diphenyliodonium iodide can be used in medicine and fruit preservation .
Cat. No.: HY-B0961
CAS No.: 129-16-8
Synonyms: Mercury dibromofluorescein disodium salt; ZP1
Merbromin is a mixed inhibitor of the 3-chymotrypsin-like protease (3CLpro) of SARS-CoV-2, with an IC50 of 2.7 μM. Merbromin effectively inhibits the replication of the Zika virus (ZIKV) and shows anti-ZIKV activity by inhibiting ZIKVpro. Merbromin can also be used as a topical disinfectant for cuts and scrapes, and it serves as a biological dye .
Cat. No.: HY-E70097
Target:  

Endogenous Metabolite

Research Areas:  

Others

Sialidase (α2-3-6-8-9) is a broadly specific sialidase that cuts linear and branched non-reducing terminal sialic acid residues from glycoproteins, glycopeptides, and oligosaccharides. Sialidase (α2-3-6-8-9) can be used for in vitro and in vivo polysaccharide analysis and characterization as well as complete glycoprotein remodeling .
Cat. No.: HY-D1668
Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .
Cat. No.: HY-P99047
CAS No.: 1318075-13-6
Synonyms: AB 0024; GS 6624
Simtuzumab (AB 0024; GS 6624) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2). Simtuzumab non-competitively blocks collagen cross-linking, reduces LOXL2 protein expression and attenuates extracellular matrix changes. Simtuzumab reduces myocardial fibrosis and prevents cardiac dysfunction. Simtuzumab lowers Myh7 and Nppa gene expression, reduces contraction heterogeneity, and cuts COL1A1 deposition. Simtuzumab can be used for the research of LMNA mutation-induced dilated cardiomyopathy, idiopathic pulmonary fibrosis, and primary sclerosing cholangitis .
Cat. No.: HY-131618
CAS No.: 744-46-7
Purity:  99.89%
Synonyms: Bz-Gly-Arg
Research Areas:  

Others

Hippuryl-Arg (Bz-Gly-Arg) is a substrate used for fluorescence detection and is commonly used in biochemical studies, especially in studying enzyme activity. The phenylalanine portion of Hippuryl-Arg is connected by an aromatic side chain, which allows it to be detected under ultraviolet light. Hippuryl-Arg is used to detect enzymes that recognize and cut peptide bonds containing arginine .
Cat. No.: HY-D3014
The Labeling Kits Centrifugation-Based Rapid Desalting Column (5KD) is a laboratory tool for rapid desalting, particularly suitable for the purification and concentration of proteins and other biological molecules. This product utilizes centrifugal force and passes through a specific filter membrane (with a molecular weight cut-off of 5KD) to effectively remove salts and other small molecule impurities from the sample.
Cat. No.: HY-P0229
CAS No.: 9026-12-4
Synonyms: Rnase T1
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Ribonulease T1, Aspergillus oryzae (Rnase T1), is commonly used in biochemical research. Ribonuclease T1 is an endonuclease that can specifically degrade single stranded RNA. Ribonuclease T1 can form nucleoside 2 ', 3 '-cyclic phosphoric acid intermediates to cut the phosphodiester bond between 3' -guanosine residues and adjacent nucleoside 5 '-OH groups to produce 3' -GMP terminal oligonucleotides .
Cat. No.: HY-147240
CAS No.: 1824609-67-7
Purity:  99.92%
Synonyms: ADX-629
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Acloproxalap (ADX-629) is an orally active reactive aldehyde species (RASP) inhibitor. Acloproxalap binds covalently to free aldehydes, sequesters reactive aldehyde species, malondialdehyde, acetaldehyde and preformed malondialdehyde-acetaldehyde adducts, and reduces elevated RASP levels. Acloproxalap decreases the formation of aldehyde adducts, reduces liver and serum triglyceride levels, hepatic fat accumulation, circulating anti-malondialdehyde-acetaldehyde adduct antibody levels, and inhibits the release of IL-6 and MCP-1. Acloproxalap improves cell viability of liver slices exposed to ethanol. Acloproxalap blocks ethanol-induced damage in animal models of alcoholic liver disease. Acloproxalap is applicable to research related to alcoholic liver disease, alcoholic fatty liver disease, non-alcoholic steatohepatitis, chronic cough, rheumatoid arthritis, ulcerative colitis and mild atopic asthma .
Cat. No.: HY-W440408
CAS No.: 25038-59-9
Synonyms: Polyester short-CUT fiber
Poly(oxyethyleneoxyterephthaloyl) is a commonly used waterproof polymer material. Poly(oxyethyleneoxyterephthaloyl) can be used in textile, electrical and other fields .
Cat. No.: HY-D2277
CAS No.: 1394821-44-3
Fluorescein-CM2 is a fluorogenic molecule that can be used to rapidly screen esterase cut sites for protein-protein interaction-dependent (PPI-dependent) esterase activity in E. coli .
Cat. No.: HY-W019711R
CAS No.: 14371-10-9
trans-Cinnamaldehyde (Standard) is the analytical standard of trans-Cinnamaldehyde. This product is intended for research and analytical applications. trans-Cinnamaldehyde can be used to prepare highly polyfunctionalized furan ring by reaction of alkyl isocyanides with dialkyl acetylenedicarboxylate . trans-Cinnamaldehyde can be used to synthesize trans-cinnamaldehyde -β-cyclodextrin complex, an antimicrobial edible coating that increases the shelf life of fresh-cut fruits .
Cat. No.: HY-124324
CAS No.: 106927-48-4
Synonyms: p-Nitopheyl β-D-cellotioside
4-Nitrophenyl β-D-cellotrioside (p-Nitopheyl β-D-cellotioside) is a chromogenic substrate for endoglucanases and cellulose biohydrolases. As a fluorescent dye, nitrophenyl β-D-Cellotrioside can be hydrolyzed by enzymes to release 4-nitrophenol, producing a yellow color. The activity of the enzyme can be quantitatively analyzed by monitoring the change in absorbance at 405 nm .
Cat. No.: HY-P10322
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Z-IETD-R110 is a fluorescent substrate of caspases. Z-IETD-R110 acts as a substrate for caspase-8. When caspase-8 is activated, it can recognize and cut Z-IETD-R110, releasing fluorophore, which can be detected by fluorescence microscopy. Z-IETD-R110 can be used to study oxidative stress-induced apoptosis, particularly in pancreatic acinar cells .
Cat. No.: HY-P11090
CAS No.: 1273551-45-3
Target:  

MHC

Research Areas:  

Inflammation/Immunology

TpD is a chimeric T-helper epitope. TpD has a special site that cathepsin can cut. Immunization with TpD produces a strong antibody response. TpD promotes long-term CD4 immune responses in animals and humans. TpD binds well to many human MHC class II types, mainly HLA-DRB1. It also binds some other HLA alleles like DRB3, DRB4, DRB5, DP, and DQ. TpD can be used to improve the immune response of peptide vaccines .
Cat. No.: HY-176437
CAS No.: 1914971-97-3
Target:  

Tyrosinase

Research Areas:  

Metabolic Disease

Tyrosinase-IN-42 (Compound 13t) is a tyrosinase inhibitor (IC50: 1.363 µM). Tyrosinase-IN-42 exhibits anti-browning effects on fresh-cut apples. Tyrosinase-IN-42 has antioxidant activity by scavenging DPPH and ABTS free radicals (IC50: 57.90 and 45.64 µM, respectively) .
Cat. No.: HY-K0247

MCE ConA Magnetic Beads can be used to isolate cells or purify glycoproteins from serum and cell extracts. It is also employed in experiments such as collecting and immobilizing cell nuclei, CUT & Run, and CUT & Tag. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.