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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Cry2
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Cry2" in MCE Product Catalog:
4
4 Cited Publications
Target:
Research Areas:
KS15 is an inhibitor of the interactions between cryptochromes (CRYs: CRY1 and CRY2) and the CLOCK:BMAL1 heterodimer. KS15 impairs the feedback actions of CRYs on E-box-dependent transcription (EC50=4.9 μM) by CLOCK:BMAL1 heterodimer, an indispensable transcriptional regulator of the mammalian circadian clock. Anti-proliferative activity [2].
2
2 Cited Publications
Target:
Research Areas:
KL001 is a first-in-class cryptochrome (CRY, a flavoproteins that are sensitive to blue light, and is involved in the circadian rhythms of plants and animals) stabilizer which specifically interacts with CRY1 and CRY2. KL001 prevents ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001 has the potential to control fasting hormone-induced gluconeogenesis [2] .
2
2 Cited Publications
Target:
Research Areas:
KL201 a circadian clock modulator, is a isoform-selective cryptochrome 1 (CRY1) stabilizer. KL201 has no stabilizing effect on CRY2. KL201 lengthens the period of circadian rhythms in cells and tissues .
Cat. No.: HY-RS03205
Target:
Research Areas:
CRY2 Human Pre-designed siRNA Set A contains three designed siRNAs for CRY2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-134192
CAS No.: 450338-32-6
Target:
Research Areas:
TH301 is a Phenylpyrazole derivative. TH301 selectively stabilize CRY2. TH301 dose-dependently prolongs circadian period .
Cat. No.: HY-P704044
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UST; Uronyl 2-Sulfotransferase; 2OST; Chondroitin Sulfate 2-O-Sulfotransferase; CS-2OST; Dermatan/Chondroitin Sulfate 2-Sulfotransferase; DS2ST
Species:
Mouse
Source:
E. coli
Cat. No.: HY-108468R
CAS No.: 309928-48-1
Target:
Research Areas:
KL001 (Standard) is the analytical standard of KL001 (HY-108468). This product is intended for research and analytical applications. KL001 is a first-in-class cryptochrome (CRY, a flavoproteins that are sensitive to blue light, and is involved in the circadian rhythms of plants and animals) stabilizer which specifically interacts with CRY1 and CRY2. KL001 prevents ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001 has the potential to control fasting hormone-induced gluconeogenesis [2] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
