26 Results for "

Cytarabine hydrochloride

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "Cytarabine hydrochloride" in MCE Product Catalog:

106
106 Publications Verification
Cat. No.: HY-13605A
CAS No.: 69-74-9
Purity:  99.67%
Synonyms: Cytosine β-D-arabinofuranoside hydrochloride; Cytosine Arabinoside hydrochloride; Ara-C hydrochloride
Cytarabine hydrochloride, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine hydrochloride has antiviral effects against HSV.
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106
106 Publications Verification
Cat. No.: HY-13605
CAS No.: 147-94-4
Purity:  99.98%
Synonyms: Cytosine β-D-arabinofuranoside; Cytosine Arabinoside; Ara-C
Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity.
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9
9 Cited Publications
Cat. No.: HY-17564
CAS No.: 3992-42-5
Synonyms: 2'-Deoxycytidine monohydrochloride; Deoxycytidine hydrochloride; NSC 83251
2'-Deoxycytidine hydrochloride (2'-Deoxycytidine monohydrochloride; NSC 83251) is an orally active nucleic acid biosynthesis enzyme inhibitor. 2'-Deoxycytidine hydrochloride competes with nucleic acid biosynthesis enzymes and nucleoside transporters, thereby reducing the toxicity of cytarabine. 2'-Deoxycytidine hydrochloride can be used in the research of L1210 lymphoblastic leukemia .
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1
1 Cited Publications
Cat. No.: HY-N0093
CAS No.: 10212-25-6
Synonyms: Cyclocytidine hydrochloride; Cyclo-CMP hydrochloride; Cyclo-C
Ancitabine (Cyclocytidine) hydrochloride is a cytarabine derivative that inhibits viral replication. Ancitabine hydrochloride blocks vaccinia virus DNA replication, the progression of viral protein synthesis from early to late stages, and one-step growth of vaccinia virus. Ancitabine hydrochloride is applicable to research related to vaccinia virus infection, leukemia, human cytomegalovirus infection and colorectal cancer .
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1
1 Cited Publications
Cat. No.: HY-14941
CAS No.: 188181-42-2
Purity:  ≥98.0%
Synonyms: CP 4055
Research Areas:  

Cancer

Elacytarabine (CP 4055) is a lipid-conjugated derivative of the nucleoside analog cytarabine. Elacytarabine (CP 4055) is an antineoplastic agent with cytotoxicity in solid tumors.
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Cat. No.: HY-16445
CAS No.: 151823-14-2
Synonyms: CS682; CYC682
Research Areas:  

Cancer

Sapacitabine is an orally available nucleoside analog proagent that is structurally related to cytarabine.
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Cat. No.: HY-160952
CAS No.: 1256639-86-7
Synonyms: CPX 351; Cytarabine-daunorubicin
Research Areas:  

Cardiovascular Disease Cancer

Cytarabine-daunorubicin (CPX 351) is a Liposomal formulation prepared from Cytarabine (HY-13605) and Daunorubicin (HY-13062A) at a fixed synergistic molar ratio of 5:1. Cytarabine-daunorubicin improves secondary acute myeloid leukemia. Cytarabine-daunorubicin can be used in research related to secondary acute myeloid leukemia, high-risk myelodysplastic syndrome, and chronic myelomonocytic leukemia .
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Cat. No.: HY-13605R
CAS No.: 147-94-4
Synonyms: Cytosine β-D-arabinofuranoside (Standard); Cytosine Arabinoside (Standard); Ara-C (Standard)
Cytarabine (Standard) is the analytical standard of Cytarabine. This product is intended for research and analytical applications. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity.
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Cat. No.: HY-115740
CAS No.: 13191-15-6
Synonyms: Ara-CTP
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Cytarabine triphosphate (Ara-CTP), an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine .
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Cat. No.: HY-115740A
CAS No.: 1179343-17-9
Purity:  ≥95.0%
Synonyms: Ara-CTP trisodium
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Cytarabine triphosphate (Ara-CTP) trisodiu, an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate trisodiu levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine .
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Cat. No.: HY-173444
CAS No.: 2989934-63-4
Research Areas:  

Cancer

HDAC11-IN-3 (Compound A9) is a selective HDAC11 inhibitor (IC50: 4.1 nM). HDAC11-IN-3 has inhibitory effects on U937 and OCI-AML2 acute myeloid leukemia (AML) cell lines (IC50: 10 μM). HDAC11-IN-3 has significant anti-AML activity, inducing apoptosis, cell cycle arrest, and differentiation. HDAC11-IN-3 upregulates the iron transporters transferrin (TF) and transferrin receptor (TFRC), and activates the p62-Keap1-Nrf2-HMOX1 pathway, which together lead to increased intracellular iron levels and induce ferroptosis in AML cells. HDAC11-IN-3 can be used alone or in combination with Cytarabine (HY-13605) for AML research .
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Cat. No.: HY-107093
CAS No.: 332863-86-2
Target:  

Apoptosis

Research Areas:  

Cancer

MBC-11 is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC). MBC-11 has the potential for tumor-induced bone disease (TIBD) research .
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Cat. No.: HY-13605S
CAS No.: 40632-26-6
Purity:  ≥98.0%
Cytarabine-d2 is the deuterium labeled Cytarabine. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV .
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Cat. No.: HY-N0093A
CAS No.: 31698-14-3
Synonyms: Cyclocytidine; Cyclo-CMP
Research Areas:  

Cancer

Ancitabine (Cyclocytidine) is a cytarabine derivative that inhibits viral replication. Ancitabine blocks vaccinia virus DNA replication, the progression of viral protein synthesis from early to late stages, and one-step growth of vaccinia virus. Ancitabine is applicable to research related to vaccinia virus infection, leukemia, human cytomegalovirus infection and colorectal cancer .
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Cat. No.: HY-W344074
CAS No.: 7075-11-8
Research Areas:  

Cancer

Cytarabine 5′-monophosphate is a metabolite of the nucleoside analog Cytarabine (HY-13605), catalyzed by deoxycytidine kinase. Cytarabine 5′-monophosphate is incorporated into DNA by DNA polymerase α, which reduces the rate of DNA synthesis. At a concentration of 15 mM, Cytarabine 5′-monophosphate inhibits nuclear and mitochondrial DNA replication in Saccharomyces cerevisiae (S. cerevisiae). Additionally, Cytarabine 5′-monophosphate (3.5-75.1 mg/kg) improves survival in leukemia mice (L1210 mice). Cytarabine 5′-monophosphate can be used in cancer research .
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Cat. No.: HY-W770279
DL-Cytarabine- 13C3 is the 13C-labeled DL-Cytarabine.
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Cat. No.: HY-W654127
Cytarabine- 13C3 5'-monophosphate is 13C labeled Cytarabine 5’-monophosphate .
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Cat. No.: HY-13605AR
CAS No.: 69-74-9
Synonyms: Cytosine β-D-arabinofuranoside hydrochloride (Standard); Cytosine Arabinoside hydrochloride (Standard); Ara-C hydrochloride (Standard)
Cytarabine (hydrochloride) (Standard) is the analytical standard of Cytarabine (hydrochloride). This product is intended for research and analytical applications. Cytarabine hydrochloride, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine hydrochloride has antiviral effects against HSV.
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Cat. No.: HY-106349
CAS No.: 73532-83-9
Synonyms: Cytarabine ocfosfate; YNK 01
Research Areas:  

Cancer

Fosteabine is an oral and proagent analogue of cytarabine which is resistant to deoxycytidine deaminase.
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Cat. No.: HY-W654126
Synonyms: Cytosine β-D-arabinofuranoside--13C3; Cytosine Arabinoside--13C3; Ara-C-13C3
Cytarabine- 13C3 (Cytosine β-D-arabinofuranoside- 13C3) is 13C labeled Cytarabine .
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