2 Results for "

DISCO

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "DISCO" in MCE Product Catalog:

Cat. No.: HY-163379
CAS No.: 2365161-92-6
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

C5aR1 antagonist 2 (Compound 6a) is an orally active C5a receptor 1 (C5aR1) antagonist that shows efficacy in inhibiting the C5a-induced neutrophil count increase. C5aR1 antagonist 2 is potent in the DISCO and migration assays, with IC50 values of 21 and 3 nM, respectively. C5aR1 antagonist 2 can be used for the research of acute and chronic inflammatory diseases .
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Cat. No.: HY-163378
CAS No.: 2365325-67-1
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

C5aR1 antagonist 1 (Compound 7e) is an orally active C5a receptor 1 (C5aR1) antagonist. C5aR1 antagonist 1 is active in DISCO and migration assays, with IC50 values of 38 nM and 17 nM, respectively. C5aR1 antagonist 1 can be used for the research of acute and chronic inflammatory diseases .
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