1 Result for "

DIX01

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DIX01" in MCE Product Catalog:

Cat. No.: HY-180836
DIX-01 is a CRBN-recruiting molecular glue and cytotoxic agent targeting GSPT1, with an EC50 of 173 nM against human GSPT1. DIX-01 drives proteasomal degradation of GSPT1, IKZF1 and IKZF3, and induces cytotoxicity in cancer cells. DIX-01 inhibits tumor growth in a zebrafish xenograft model and can be used for research on acute myeloid leukemia and prostate cancer .
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