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Derris indica

" in MedChemExpress (MCE) Product Catalog:

2

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Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N17803

    3,3',4',7-Tetramethoxyflavone

    Others Others
    Fisetin tetramethyl ether (3,3',4',7-Tetramethoxyflavone) is a flavonoid compound. Fisetin tetramethyl ether can be isolated from the stem bark of Derris indica. Fisetin tetramethyl ether shows no inhibitory activity against the formation of advanced glycation end products .
    Fisetin tetramethyl ether
  • HY-180324

    Bcl-2 Family Caspase p38 MAPK MMP Apoptosis Bacterial DNA/RNA Synthesis Survivin Infection Cancer
    Candidone is a type of flavanone phenolic compound with anti-cancer and antibacterial activities. Candidone inhibits the proliferation of hepatoblastoma and cholangiocarcinoma cells and induces their apoptosis by up-regulating p21, Bax, and caspase 3/9, and down-regulating Bcl-2 and survivin. It reduces the metastatic ability of cancer cells by inhibiting the expression of phosphorylated p38 and matrix metalloproteinase MMP-9. Candidone has inhibitory effects on multidrug-resistant bacterial strains. Candidone binds to the base pairs of DNA in a groove-binding manner, thereby slightly altering the conformation of DNA .
    Candidone

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