1 Result for "

EP39

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EP39" in MCE Product Catalog:

Cat. No.: HY-150536
Target:  

HIV HIV Protease

Research Areas:  

Infection

EP39 is a potent HIV-1 maturation inhibitor. EP39 interacts with the SP1 domain of Gag. EP39 decreases the dynamics of CA-SP1 junction, by binding to the QVT motif of the SP1 domain, and perturbs the natural coil-helix equilibrium on both sides of the SP1 domain by stabilizing the transient alpha helical structure. EP39 acts by arresting maturation of HIV-1 thereby blocking its infectivity .
loading...
    loading...